Polymer-based microfluidic device for on-chip counter-diffusive crystallization and <i>in situ</i> X-ray crystallography at room temperature
Category
Published on
Type
journal-article
Author
Sarthak Saha and Can Özden and Alfred Samkutty and Silvia Russi and Aina Cohen and Margaret M. Stratton and Sarah L. Perry
Citation
Saha, S., Özden, C., Samkutty, A., Russi, S., Cohen, A., Stratton, M. M., & Perry, S. L. (2023). Polymer-based microfluidic device for on-chip counter-diffusive crystallization and in situ X-ray crystallography at room temperature. Lab on a Chip, 23(8), 2075–2090. https://doi.org/10.1039/d2lc01194h
Abstract
Here we have reported novel polymeric devices to control fluid flow using surface forces and capillary action to facilitate counter-diffusive, on-chip protein crystallization.
DOI
Funding
NSF-STC Biology with X-ray Lasers (NSF-1231306)