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Sugar ring alignment and dynamics underline cytarabine and gemcitabine inhibition on Pol η catalyzed DNA synthesis

By Caleb Chang, Grace Zhou, Christie Lee Luo, Sarah Eleraky, Madeline Moradi, Yang Gao

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Category

BioXFEL Publications

Published on

Type

journal-article

Author

Caleb Chang and Grace Zhou and Christie Lee Luo and Sarah Eleraky and Madeline Moradi and Yang Gao

Citation

Chang, C., Zhou, G., Lee Luo, C., Eleraky, S., Moradi, M., & Gao, Y. (2024). Sugar ring alignment and dynamics underline cytarabine and gemcitabine inhibition on Pol η catalyzed DNA synthesis. Journal of Biological Chemistry, 300(6), 107361. https://doi.org/10.1016/j.jbc.2024.107361

DOI

http://dx.doi.org/10.1016/j.jbc.2024.107361

Funding

NSF-STC Biology with X-ray Lasers (NSF-1231306)