Support

BioXFEL STC 2nd Annual International Conference

Category: Meeting

Sponsored in part by:         On behalf of the National Science Foundation’s BioXFEL Science and Technology Center and Conference Co-chairs, Dr. Eaton Lattman and Dr. Abbas Ourmazd, we’d like to thank you for attending …

European XFEL Users Meeting

Category: Meeting

28–30 January 2015 at DESY, Hamburg, Germany The European XFEL Users’ Meeting is an annual opportunity to strengthen the interaction between the European XFEL project and the scientific user community. The scope of this meeting includes: Progress and current status of the European …

BioXFEL Lecture Series - Nanocrystallography

Category: Seminar

Joe Luft will describe the theory and practice behind crystallography and nanocrystallography and discuss recent advances in the production, characterization, and optimization of nanocrystals.  Click here to access the livestream

BioXFEL Journal Club with Bahige Abdallah (ASU) & Ganesh Subramanian (ASU)

Category: Seminar

Bobby Abdallah, a graduate student in the Ros Lab at Arizona State University, will present the article: "Tenbauer, J., Basu, S., et. al. (2014). Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein. Science." …

New study brings medicine closer to non-addictive painkillers

Category: General

New study brings medicine closer to non-addictive painkillers Posted: February 27, 2015 Powerful opiate drugs are a mainstay in modern medicine, alleviating pain in both acute and chronic forms. These charms however, bear a curse. Users quickly develop tolerance to their effects, requiring …

Deadline for EMBL Group Leader Applications

Category: General

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BioXFEL Lecture Series - Richard Kirian

Category: Seminar

Every month a BioXFEL scientist or collaborator gives a presentation on their research or a related topic. This February, Dr. Richard Kirian will be presenting. Dr. Kirian participates in a variety of XFEL experiments, and regularly contributes to the development of software (Cheetah and CrystFEL) …

BioXFEL Journal Club with George Calvey (Cornell)

Category: Seminar

George Calvey, a graduate student in the Pollack Lab at Cornell University, will present the article: "Kirian, R., Bean, R., et al. (2014). Phasing coherently illuminated nanocrystals bounded by partial unit cells. Phil Trans B. " 3:00 pm - 4:00 pm EST Please contact Bill Bauer for more …

LCLS Beamtime - Schmidt

Category: Experiment

LG09 - Macromolecular Dynamics with Femtosecond Time Resolution  CXI station

Second Meeting of the BioXFEL Center External Advisors

Category: Meeting

The external advisors to the BioXFEL Center will convene at Arizona State University for an update on Center activities. The Center external advisors are Keith Moffatt, James Naismith, Martin Caffrey, Victor Lamzin, Wah Chiu, Dirksen Bussiere, Henry Frierson, Teresa Head-Gordon, Nora Berrah and …

LCLS Beamtime - Zatsepin

Category: Experiment

LI63 - Dynamics of electron transfer between Photosystem I and ferredoxin  CXI station

The 1st SACLA Workshop on Femtosecond Crystallography

Category: Workshop

BioXFEL Presenters include:  Henry Chapman (DESY), Uwe Weierstall (ASU), Vadim Cherezov (Scripps), and Petra Fromme (ASU) The 1st SACLA Workshop on Femtosecond Crystallography Date: March 26-27, 2015 Place: Conference room on 2F at SACLA Registration: Registration is free. Please send your …

LCLS Beamtime - Cherezov

Category: Experiment

LH01 - Femtosecond Crystallography of G protein-Coupled Receptors in Lipidic Cubic Phase CXI station

LCLS Beamtime - Coulton

Category: Experiment

LH08 - Serial Femtosecond Crystallographic Studies of Membrane Proteins for Bacterial Iron Acquisition  CXI station

LCLS Beamtime - Protein Crystal Screening

Category: Experiment

1 um PCS CXI station Schedule of PCS beam times will be posted when released.  

BioXFEL Journal Club with Joey Olmos ( Rice)

Category: Seminar

Joey Olmos, a graduate student in the Phillips Lab at Rice University will present the article: "Weierstall, U., James, D., et al. (2014). Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nat Commun 5, 3309. …

LCLS Beamtime - Neutze

Category: Experiment

LH95 - Do ultrafast coherent motions occur in photosynthetic reaction centers? CXI station

ASU Biophysics Seminars - Artem Lyubimov

Category: Seminar

Capture and X-ray Diffraction Studies of Protein Microcrystals in a Microfluidic Trap Array 3:30 PM PDTArtem Lyubimov Stanford University Host: Richard Kirian X-ray free electron lasers (XFELs) promise to enable the collection of interpretable diffraction data from samples refractory to data …

LCLS Beamtime - Watkins

Category: Experiment

LI55 - The Picosecond and Nanosecond Dynamics of Nucleic Acid Tertiary Structures.   XPP station

LCLS Beamtime - Weik

Category: Experiment

LI56 - Visualizing early photo-intermediates in a light-switchable fluorescent protein using femtosecond time-resolved SFX  CXI station

Science Director Dr. John Spence named Royal Society Fellow

Category: General

Details Published on Tuesday, 05 May 2015 09:40 Professor John Spence ForMemRS (reprinted from royalsociety.org) Richard Snell Professor of Physics, Department of Physics, Arizona State University and Director of Science, NSF BioXFEL Science and Technology Center Professor John Spence …

BioXFEL Lecture Series - 2D Crystallography

Category: Seminar

May 6th, 3:00 - 4:30 PM (EST) Many membrane proteins are recalcitrant to forming 3-dimensional crystals for structural investigation by X-ray diffraction, yet readily form 2-dimensional crystals. 2D protein crystallography has to date only been performed with electron diffraction, however it is …

BioXFEL Journal Club with Tyler Norwood (UWM) & Prakash Nepal (UWM)

Category: Seminar

Tyler Norwood, an undergraduate student in the Schmidt Lab at the University of Wisconsin-Milwaukee, will present the article: "Abdallah, B. G., Kupitz, C., et al. (2013). Crystallization of the Large Membrane Protein Complex Photosystem I in a Microfluidic Channel. ACS Nano 7 (12), pp 10534-10543 …

HWI Crystallization Workshop 2015 for BioXFEL Students and Postdoctoral Scholars

Category: Workshop

Sponsored in part by: Please note agenda is subject to change. Day 1 Lectures, Tuesday, June 2, 2015 – Flickinger Lecture Hall TIME TOPIC PRESENTER 8:30 - 9:00 am Light breakfast in HWI atrium All 9:00 - 9:05 am Welcome to the …

BioXFEL STC 2015 2nd Annual Site Visit

Category: Meeting

The Center will be holding its Second Annual Site Visit June 3-5, 2015.  Below is a very general outline of the week’s agenda. June 2 nd & 3 rd :  Crystal Growth Workshop June 3 rd :  Prep Day & Group Dinner at Pearl Street Grill and Brewery June 4 th :  NSF Review June 5 th …

LCLS Beamtime - Single Particle Imaging

Category: Experiment

CXI Station

BioXFEL Journal Club with Shibom Basu (ASU) and Rob Lawrence (ASU)

Category: Seminar

Please join us for our live-recorded Journal Club Wednesday, June 17th at  3PM (UTC-4, EDT), 2PM (CDT), 1PM (MDT), 12PM (PDT, MST).   Shibom Basu is a graduate student from India, working on the data analysis part of Femtosecond Nanocrystallography project, mostly focused on solving x-ray …

LCLS Beamtime - Obertheur

Category: Experiment

LH96 - Optimized sample delivery with a pulsed and liquid-liquid focused jet for SFX structure determination of RNA polymerases  CXI station

BioXFEL Lecture Series - Single Particle Imaging

Category: Seminar

Dr. Saldin’s research covers all aspects of the use of radiation to study matter, and diffraction and scattering phenomena. His particular interests center around holography, tomography, and x-ray scattering from biomolecules. He obtained his B.A in 1971 and his Ph.D. in Materials in 1975, both …

Webinar by Thomas White on CrystFEL - data processing for serial crystallography

Category: Seminar

Tune in online on Tuesday, July 14th at 12pm EDT to hear Thomas White's presentation on CrystFEL, a data processing suite for data acquired "serially".  Details of how to log in are here: https://sbgrid.org/news/sbgrid-lunch-break-thomas-white-2015-06-22Tuesday, July 14th at 12pm EDTThomas White …

BioXFEL Journal Club with Ahmad Hosseinizadeh (UWM) & Christopher Kuptiz (UWM)

Category: Seminar

Ahmad Hosseinizadeh, a postdoc at the University of Wisconsin-Milwaukee, will present the article: "Arnlund, D., Johansson, L. C., et al. (2014). Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser. Nature methods. " Christopher Kuptiz, a postdoc in the …

2015 Serial Crystallography Data Analysis Workshop at the American Crystallographic Association Annual Meeting

Category: Workshop

We are running a serial femtosecond crystallography data analysis workshop at ACA 2015 in Philadelphia, PA, focused on "Serial Crystallography Data Analysis with Cheetah and CrystFEL: Concepts and Tutorials".  www.amercrystalassn.org/2015-wk.02 Online tutorial for LCLS data …

2015 NSF STC Professional Development Workshop

Category: Workshop

The NSF is excited to announce a National Science Foundation sponsored professional development workshop for advanced Ph.D. students and postdocs. This all expense-paid workshop is designed to help participants succeed in both academic and industrial careers by providing them with a wide range of …

LCLS Beamtime - Single Particle Imaging

Category: Experiment

Single Particle Imaging AMO station

BioXFEL August Journal Club

Category: Seminar

Please join us Wednesday, August 19th at 3PM EST / 2PM CDT/ 12 MST for our monthly journal club. Session 1: Yun Zhao (ASU) Yefanov, O., Gati, C., et al. (2014). 3D merge: mapping the continuous reciprocal space intensity distribution of serial crystallography data. Phil Trans B. Full article …

BioXFEL Lecture Series - Solution Scattering at XFELS - Dr. Pollack

Category: Seminar

Dr. Lois Pollack of Cornell University will be presenting a lecture entitled "Using X-rays to measure the solution structures of biomolecules: the present state of the art and how XFELS can advance it" This lecture will introduce solution scattering as a method of determining low resolution …

September BioXFEL Journal Club with Rahel Woldeyes (UCSF) and Jonathan Clinger (Rice)

Category: Seminar

For our September BioXFEL Journal Clubs we have 2 students presenting XFEL-related research papers. Rahel Woldeyes, a graduate student from UCSF, will present: "Liu, H., Zatsepin, N. A., et al. (2013). Ab-initio phasing using nanocrystal shape transforms with incomplete unit cells. IUCrJ 1, …

UWM Fall Workshop

Category: Workshop

How do you make a movie of a single particle jiggling and wiggling with atomic resolution and ultra-fast temporal resolution? How do you calculate the energy landscape or the kinetics/dynamics of a sequence of conformational changes? What do you do with millions and millions of snapshots, each for …

October Journal Club Presentation by Chufeng Li (ASU) and Austin Echelmeier (ASU)

Category: Seminar

Chufeng Li (ASU) and Austin Echelmeier (ASU) will be presenting the following papers:   1. The indexing ambiguity in serial femtosecond crystallography (SFX) resolved using an expectation maximization algorithm. Liu, H. & Spence, J. C. (2014). IUCrJ, 1, 0-0 Here 2. Serial femtosecond …

Arizona State University Biophysics Seminar - Tamir Gonen

Category: Seminar

MicroED - 3D electron crystallography Dr. Tamir Gonen We demonstrate that it is feasible to determine high-resolution protein structures by electron crystallography of three-dimensional crystals in an electron cryo-microscope (CryoEM). Lysozyme microcrystals were frozen on an electron microscopy …

LCLS Beamtime - Fromme

Category: Experiment

LJ49 - Structural dynamics of water splitting and electron transfer in Photosystem II  CXI Station

BioXFEL Lecture Series - Geometry of X-ray crystallographic diffraction and the Ewald sphere - George Phillips

Category: Seminar

Every month, BioXFEL hosts an online seminar featuring one of our scientists or collaborators in an effort to educate our members and the scientific community. This seminar series features a live broadcast of the lecture and is recorded and posted to our website. In November, Dr. George Phillips …

November Journal Club by Max Wiedorn (CFEL)

Category: Seminar

Max Wiedorn (CFEL) Will present the following paper: 1. Data collection strategies for time-resolved X-ray free-electron laser diffraction, and 2-color methods. C Li, K Schmidt, JC Spence - Structural Dynamics, 2015. http://scitation.aip.org/content/aca/journal/sdy/2/4/10.1063/1.4922433  …

LCLS Beamtime - Standfuss

Category: Experiment

LK27 - Ultrafast structural dynamics of light-triggered membrane pumps and channels in native- like lipidic cubic phase  CXI Station

BioXFEL Lecture Series - Multitemperature Data and Diffuse Scattering in X-ray Crystallography -James Fraser

Category: Seminar

Every month, BioXFEL hosts an online seminar featuring one of our scientists or collaborators in an effort to educate our members and the scientific community. This seminar series features a live broadcast of the lecture and is recorded and posted to our website. This December, Dr. James Fraser …

LCLS Beamtime - Schmidt

Category: Experiment

LK17 - Time-Resolved Serial Femtosecond Nanocrystallography to Establish Structure-Based Enzymology at the LCLS  CXI Station

LCLS Beamtime - Cherezov

Category: Experiment

LJ24 - Femtosecond Crystallography of G protein-Coupled Receptors in Lipidic Cubic Phase  CXI Station

LCLS Beamtime - Wang

Category: Experiment

LK43 - RNA Structure Determination by SFX  CXI Station

LCLS Beamtime - Zatsepin

Category: Experiment

LK83 - Protein Crystal Screening CXI Station