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  1. Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 inStreptomyces globisporus

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    25 Aug 2016 | BioXFEL Publications | Contributor(s): Chin-Yuan Chang, Jeremy R. Lohman, Hongnan Cao, Kemin Tan, Jeffrey D. Rudolf, Ming Ma, Weijun Xu, Craig A. Bingman, Ragothaman M. Yennamalli, Lance Bigelow, Gyorgy Babnigg, Xiaohui Yan, Andrzej Joachimiak, George Phillips, Ben Shen

    http://dx.doi.org/10.1021/acs.biochem.6b00713 Chin-Yuan Chang and Jeremy R. Lohman and Hongnan Cao and Kemin Tan and Jeffrey D. Rudolf and Ming Ma and Weijun Xu and Craig A. Bingman and Ragothaman M. Yennamalli and Lance Bigelow and Gyorgy Babnigg and Xiaohui Yan and Andrzej Joachimiak and George …

  2. Electron Crystallography, Charge-Density Mapping and Nanodiffraction

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    24 Aug 2016 | BioXFEL Publications | Contributor(s): John Spence

    book-chapter http://dx.doi.org/10.1007/978-3-319-26651-0_5 Spence, J., 2016. Electron Crystallography, Charge-Density Mapping and Nanodiffraction. Transmission Electron Microscopy, pp.145–166. Available at: http://dx.doi.org/10.1007/978-3-319-26651-0_5. John Spence

  3. Serial Femtosecond Crystallography of Membrane Proteins

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    23 Aug 2016 | BioXFEL Publications | Contributor(s): Lan Zhu, Uwe Weierstall, Vadim Cherezov, Wei Liu

    book-chapter http://dx.doi.org/10.1007/978-3-319-35072-1_11 NSF-STC Biology with X-ray Lasers (NSF-1231306) Zhu, L. et al., 2016. Serial Femtosecond Crystallography of Membrane Proteins. The Next Generation in Membrane Protein Structure Determination, pp.151–160. Available at: …

  4. Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography

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    22 Aug 2016 | BioXFEL Publications | Contributor(s): Przemyslaw Nogly, Valerie Panneels, Garrett Charles Nelson, Cornelius Gati, Tetsunari Kimura, Christopher Milne, Despina Milathianaki, Minoru Kubo, Wenting Wu, Chelsie E Conrad, Jesse David Coe, Richard Bean, Yun Zhao, Petra Båth, Robert Dods, Rajiv Harimoorthy, Kenneth R. Beyerlein, Jan Rheinberger, Daniel James, Daniel DePonte, Chufeng Li, Leonardo Sala, Garth J. Williams, Mark S. Hunter, Jason E. Koglin, Peter Berntsen, Eriko Nango, So Iwata, Henry Chapman, Petra Fromme, Matthias Frank, Rafael Abela, Sébastien Boutet, Anton Barty, Thomas A. White, Uwe Weierstall, John Spence, Richard Neutze, Gebhard F.X. Schertler, Jörg Standfuss

    http://dx.doi.org/10.1038/ncomms12314 Przemyslaw Nogly and Valerie Panneels and Garrett Nelson and Cornelius Gati and Tetsunari Kimura and Christopher Milne and Despina Milathianaki and Minoru Kubo and Wenting Wu and Chelsie Conrad and Jesse Coe and Richard Bean and Yun Zhao and Petra Båth and …

  5. An Introduction to X-Ray Diffraction Physics

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    10 Aug 2016 | Teaching Materials | Contributor(s): Blessing

    These notes present basic principles of the physics that underlies X-ray analysis of the atomic structure of matter. In particular, classical electromagnetic wave theory of X-ray scattering by electrons and atoms is described as background for subsequent study of X-ray diffraction methods for …

  6. Structure of the ent -Copalyl Diphosphate Synthase PtmT2 from Streptomyces platensis CB00739, a Bacterial Type II Diterpene Synthase

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    04 Aug 2016 | BioXFEL Publications | Contributor(s): Jeffrey D. Rudolf, Liao-Bin Dong, Hongnan Cao, Catherine Hatzos-Skintges, Jerzy Osipiuk, Michael Endres, Chin-Yuan Chang, Ming Ma, Gyorgy Babnigg, Andrzej Joachimiak, George Phillips, Ben Shen

    http://dx.doi.org/10.1021/jacs.6b04317 Jeffrey D. Rudolf and Liao-Bin Dong and Hongnan Cao and Catherine Hatzos-Skintges and Jerzy Osipiuk and Michael Endres and Chin-Yuan Chang and Ming Ma and Gyorgy Babnigg and Andrzej Joachimiak and George N. Phillips and Ben Shen Rudolf, J.D. et al., 2016. …

  7. Enhanced hydrogenation activity and diastereomeric interactions of methyl pyruvate co-adsorbed with R-1-(1-naphthyl)ethylamine on Pd(111)

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    04 Aug 2016 | BioXFEL Publications | Contributor(s): Mausumi Mahapatra, Luke Burkholder, Michael Garvey, Yun Bai, Dilano Saldin, Wilfred T. Tysoe

    http://dx.doi.org/10.1038/ncomms12380 Mausumi Mahapatra and Luke Burkholder and Michael Garvey and Yun Bai and Dilano K. Saldin and Wilfred T. Tysoe Mahapatra, M. et al., 2016. Enhanced hydrogenation activity and diastereomeric interactions of methyl pyruvate co-adsorbed with …

  8. Succinyl-5-aminoimidazole-4-carboxamide-1-ribose 5′-Phosphate (SAICAR) Activates Pyruvate Kinase Isoform M2 (PKM2) in Its Dimeric Form

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    02 Aug 2016 | BioXFEL Publications | Contributor(s): Ming Yan, Srinivas Chakravarthy, Joshua M. Tokuda, Lois Pollack, Gregory D. Bowman, Young-Sam Lee

    journal-article http://dx.doi.org/10.1021/acs.biochem.6b00658 Yan, M. et al., 2016. Succinyl-5-aminoimidazole-4-carboxamide-1-ribose 5′-Phosphate (SAICAR) Activates Pyruvate Kinase Isoform M2 (PKM2) in Its Dimeric Form. Biochemistry, 55(33), pp.4731–4736. Available at: …

  9. Coherent diffraction of single Rice Dwarf virus particles using hard X-rays at the Linac Coherent Light Source

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    29 Jul 2016 | BioXFEL Publications | Contributor(s): Anna Munke, Jakob Andreasson, Andrew Aquila, Salah Awel, Kartik Ayyer, Anton Barty, Richard J. Bean, Peter Berntsen, Johan Bielecki, Sébastien Boutet, Maximilian Bucher, Henry Chapman, Benedikt J. Daurer, Hasan Demirci, Veit Elser, Petra Fromme, Janos Hajdu, Max F. Hantke, Akifumi Higashiura, Brenda Hogue, Ahmad Hosseinizadeh, Yoonhee Kim, Richard Kirian, Hemanth K.N. Reddy, Ti-Yen Lan, Daniel S.D. Larsson, Haiguang Liu, N. Duane Loh, Filipe R.N.C. Maia, Adrian P. Mancuso, Kerstin Mühlig, Atsushi Nakagawa, Daewoong Nam, Garrett Charles Nelson, Carl Nettelblad, Kenta Okamoto, Abbas Ourmazd, Max Rose, Gijs Van Der Schot, Peter Schwander, M. Marvin Seibert, Jonas A. Sellberg, Raymond G. Sierra, Changyong Song, Martin Svenda, Nicusor Timneanu, Ivan A. Vartanyants, Daniel Westphal, Max Oliver Wiedorn, Garth J. Williams, Paulraj Lourdu Xavier, Chun Hong Yoon, James D Zook

    http://dx.doi.org/10.1038/sdata.2016.64 Anna Munke and Jakob Andreasson and Andrew Aquila and Salah Awel and Kartik Ayyer and Anton Barty and Richard J. Bean and Peter Berntsen and Johan Bielecki and Sébastien Boutet and Maximilian Bucher and Henry N. Chapman and Benedikt J. Daurer and Hasan …

  10. A data set from flash X-ray imaging of carboxysomes

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    29 Jul 2016 | BioXFEL Publications | Contributor(s): Max F. Hantke, Dirk Hasse, Tomas Ekeberg, Katja John, Martin Svenda, Duane Loh, Andrew V. Martin, Nicusor Timneanu, Daniel S.D. Larsson, Gijs Van Der Schot, Gunilla H. Carlsson, Margareta Ingelman, Jakob Andreasson, Daniel Westphal, Bianca Iwan, Charlotte Uetrecht, Johan Bielecki, Mengning Liang, Francesco Stellato, Daniel P. DePonte, Sadia Bari, Robert Hartmann, Nils Kimmel, Richard Kirian, M. Marvin Seibert, Kerstin Mühlig, Sebastian Schorb, Ken Ferguson, Christoph Bostedt, Sebastian Carron, John D. Bozek, Daniel Rolles, Artem Rudenko, Lutz Foucar, Sascha W. Epp, Henry Chapman, Anton Barty, Inger Andersson, Janos Hajdu, Filipe R.N.C. Maia

    http://dx.doi.org/10.1038/sdata.2016.61 Max F. Hantke and Dirk Hasse and Tomas Ekeberg and Katja John and Martin Svenda and Duane Loh and Andrew V. Martin and Nicusor Timneanu and Daniel S.D. Larsson and Gijs van der Schot and Gunilla H. Carlsson and Margareta Ingelman and Jakob Andreasson and …

  11. Single-shot diffraction data from the Mimivirus particle using an X-ray free-electron laser

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    29 Jul 2016 | BioXFEL Publications | Contributor(s): Tomas Ekeberg, Martin Svenda, M. Marvin Seibert, Chantal Abergel, Filipe R.N.C. Maia, Virginie Seltzer, Daniel P. DePonte, Andrew Aquila, Jakob Andreasson, Bianca Iwan, Olof Jönsson, Daniel Westphal, Duško Odić, Inger Andersson, Anton Barty, Meng Liang, Andrew V. Martin, Lars Gumprecht, Holger Fleckenstein, Saša Bajt, Miriam Barthelmess, Nicola Coppola, Jean-Michel Claverie, N. Duane Loh, Christoph Bostedt, John D. Bozek, Jacek Krzywinski, Marc Messerschmidt, Michael J. Bogan, Christina Y. Hampton, Raymond G. Sierra, Matthias Frank, Robert L. Shoeman, Lukas Lomb, Lutz Foucar, Sascha W. Epp, Daniel Rolles, Artem Rudenko, Robert Hartmann, Andreas Hartmann, Nils Kimmel, Peter Holl, Georg Weidenspointner, Benedikt Rudek, Benjamin Erk, Stephan Kassemeyer, Ilme Schlichting, Lothar Strüder, Joachim Ullrich, Carlo Schmidt, Faton Krasniqi, Günter Hauser, Christian Reich, Heike Soltau, Sebastian Schorb, Helmut Hirsemann, Cornelia Wunderer, Heinz Graafsma, Henry Chapman, Janos Hajdu

    http://dx.doi.org/10.1038/sdata.2016.60 Tomas Ekeberg and Martin Svenda and M. Marvin Seibert and Chantal Abergel and Filipe R.N.C. Maia and Virginie Seltzer and Daniel P. DePonte and Andrew Aquila and Jakob Andreasson and Bianca Iwan and Olof Jönsson and Daniel Westphal and Duško Odić and Inger …

  12. Open data set of live cyanobacterial cells imaged using an X-ray laser

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    29 Jul 2016 | BioXFEL Publications | Contributor(s): Gijs Van Der Schot, Martin Svenda, Filipe R.N.C. Maia, Max F. Hantke, Daniel P. DePonte, M. Marvin Seibert, Andrew Aquila, Joachim Schulz, Richard Kirian, Mengning Liang, Francesco Stellato, Sadia Bari, Bianca Iwan, Jakob Andreasson, Nicusor Timneanu, Johan Bielecki, Daniel Westphal, Francisca Nunes De Almeida, Duško Odić, Dirk Hasse, Gunilla H. Carlsson, Daniel S.D. Larsson, Anton Barty, Andrew V. Martin, Sebastian Schorb, Christoph Bostedt, John D. Bozek, Sebastian Carron, Ken Ferguson, Daniel Rolles, Artem Rudenko, Sascha W. Epp, Lutz Foucar, Benedikt Rudek, Benjamin Erk, Robert Hartmann, Nils Kimmel, Peter Holl, Lars Englert, N. Duane Loh, Henry Chapman, Inger Andersson, Janos Hajdu, Tomas Ekeberg

    http://dx.doi.org/10.1038/sdata.2016.58 Gijs van der Schot and Martin Svenda and Filipe R.N.C. Maia and Max F. Hantke and Daniel P. DePonte and M. Marvin Seibert and Andrew Aquila and Joachim Schulz and Richard A. Kirian and Mengning Liang and Francesco Stellato and Sadia Bari and Bianca Iwan and …

  13. Serial femtosecond crystallography datasets from G protein-coupled receptors

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    29 Jul 2016 | BioXFEL Publications | Contributor(s): Thomas A. White, Anton Barty, Wei Liu, Andrii Ishchenko, Haitao Zhang, Cornelius Gati, Nadia Zatsepin, Shibom Basu, Dominik Oberthür, Markus Metz, Kenneth R. Beyerlein, Chun Hong Yoon, Oleksandr M. Yefanov, Daniel James, Dingjie Wang, Marc Messerschmidt, Jason E. Koglin, Sébastien Boutet, Uwe Weierstall, Vadim Cherezov

    http://dx.doi.org/10.1038/sdata.2016.57 Thomas A. White and Anton Barty and Wei Liu and Andrii Ishchenko and Haitao Zhang and Cornelius Gati and Nadia A. Zatsepin and Shibom Basu and Dominik Oberthür and Markus Metz and Kenneth R. Beyerlein and Chun Hong Yoon and Oleksandr M. Yefanov and Daniel …

  14. Full inactivation of alphaviruses in single particle and crystallized forms

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    26 Jul 2016 | BioXFEL Publications | Contributor(s): Robert M Lawrence, James D Zook, Brenda Hogue

    http://dx.doi.org/10.1016/j.jviromet.2016.07.020 Robert M. Lawrence and James D. Zook and Brenda G. Hogue Lawrence, R.M., Zook, J.D. & Hogue, B.G., 2016. Full inactivation of alphaviruses in single particle and crystallized forms. Journal of Virological Methods, 236, pp.237–244. Available at: …

  15. XFEL data analysis for structural biology

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    21 Jul 2016 | BioXFEL Publications | Contributor(s): Haiguang Liu, John Spence

    http://dx.doi.org/10.1007/s40484-016-0076-z Haiguang Liu and John C. H. Spence Liu, H. & Spence, J.C.H., 2016. XFEL data analysis for structural biology. Quantitative Biology, 4(3), pp.159–176. Available at: http://dx.doi.org/10.1007/s40484-016-0076-z. NSF-STC Biology with X-ray Lasers …

  16. Improving the efficiency of molecular replacement by utilizing a new iterative transform phasing algorithm

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    15 Jul 2016 | BioXFEL Publications | Contributor(s): Hongxing He, Hengrui Fang, Mitchell Miller, George Phillips, Wu-Pei Su

    An iterative transform method proposed previously for direct phasing of high-solvent-content protein crystals is employed for enhancing the molecular-replacement (MR) algorithm in protein crystallography. Target structures that are resistant to conventional MR due to insufficient similarity between …

  17. Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027

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    13 Jul 2016 | BioXFEL Publications | Contributor(s): Tingting Huang, Chin-Yuan Chang, Jeremy R Lohman, Jeffrey D Rudolf, Youngchang Kim, Changsoo Chang, Dong Yang, Ming Ma, Xiaohui Yan, Ivana Crnovcic, Lance Bigelow, Shonda Clancy, Craig A Bingman, Ragothaman M Yennamalli, Gyorgy Babnigg, Andrzej Joachimiak, George Phillips, Ben Shen

    http://dx.doi.org/10.1038/ja.2016.88 Tingting Huang and Chin-Yuan Chang and Jeremy R Lohman and Jeffrey D Rudolf and Youngchang Kim and Changsoo Chang and Dong Yang and Ming Ma and Xiaohui Yan and Ivana Crnovcic and Lance Bigelow and Shonda Clancy and Craig A Bingman and Ragothaman M Yennamalli and …

  18. Opposing Effects of Multivalent Ions on the Flexibility of DNA and RNA

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    06 Jul 2016 | BioXFEL Publications | Contributor(s): Aleksander V. Drozdetski, Igor S. Tolokh, Lois Pollack, Nathan Baker, Alexey V. Onufriev

    http://dx.doi.org/10.1103/physrevlett.117.028101 journal-article Drozdetski, A.V. et al., 2016. Opposing Effects of Multivalent Ions on the Flexibility of DNA and RNA. Physical Review Letters, 117(2). Available at: http://dx.doi.org/10.1103/physrevlett.117.028101. Aleksander V. Drozdetski and …

  19. Special issue on imaging the dynamic structure of matter

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    30 Jun 2016 | BioXFEL Publications | Contributor(s): Heinrich Schwoerer, Henry Chapman, Bradley J Siwick, R J Dwayne Miller

    http://dx.doi.org/10.1088/0953-4075/49/15/150201 journal-article Schwoerer, H. et al., 2016. Special issue on imaging the dynamic structure of matter. Journal of Physics B: Atomic, Molecular and Optical Physics, 49(15), p.150201. Available at: http://dx.doi.org/10.1088/0953-4075/49/15/150201. …

  20. Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways

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    28 Jun 2016 | BioXFEL Publications | Contributor(s): Tyler D. Huber, Fengbin Wang, Shanteri Singh, Brooke R. Johnson, Jianjun Zhang, Manjula Sunkara, Steven G. Van Lanen, Andrew J. Morris, George Phillips, Jon S. Thorson

    http://dx.doi.org/10.1021/acschembio.6b00348 journal-article Huber, T.D. et al., 2016. Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways. ACS Chemical Biology, 11(9), pp.2484–2491. Available at: http://dx.doi.org/10.1021/acschembio.6b00348. Tyler D. Huber and …

  21. Imaging enzyme kinetics at atomic resolution

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    28 Jun 2016 | BioXFEL Publications | Contributor(s): John Spence, Eaton E Lattman

    http://dx.doi.org/10.1107/s2052252516010204 John Spence and Eaton Lattman Spence, J. & Lattman, E., 2016. Imaging enzyme kinetics at atomic resolution. IUCrJ, 3(4), pp.228–229. Available at: http://dx.doi.org/10.1107/s2052252516010204. journal-article

  22. Second harmonic generation correlation spectroscopy for characterizing translationally diffusing protein nanocrystals

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    24 Jun 2016 | BioXFEL Publications | Contributor(s): Ximeng Y. Dow, Christopher M. Dettmar, Emma L. DeWalt, Justin A. Newman, Alexander R. Dow, Shatabdi Roy-Chowdhury, Jesse David Coe, Christopher Kupitz, Petra Fromme, Garth J. Simpson

    Second harmonic generation correlation spectroscopy (SHG-CS) is demonstrated as a new approach to protein nanocrystal characterization. A novel line-scanning approach was performed to enable autocorrelation analysis without sample damage from the intense incident beam. An analytical model for …

  23. Optical Cryoimaging Reveals a Heterogeneous Distribution of Mitochondrial Redox State in ex vivo Guinea Pig Hearts and its Alteration during Ischemia and Reperfusion

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    15 Jun 2016 | BioXFEL Publications | Contributor(s): Mahsa Ranji, Mohammad M. Motlagh, Fahimeh Salehpor, Reyhaneh Sepehr, James S. Heisner, Ranjan K. Dash, Amadou K. S. Camara

    journal-article http://dx.doi.org/10.1109/jtehm.2016.2570219 Ranji, M. et al., 2016. Optical Cryoimaging Reveals a Heterogeneous Distribution of Mitochondrial Redox State in ex vivo Guinea Pig Hearts and its Alteration during Ischemia and Reperfusion. IEEE Journal of Translational Engineering in …

  24. Extracting water and ion distributions from solution x-ray scattering experiments

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    03 Jun 2016 | BioXFEL Publications | Contributor(s): Hung T. Nguyen, Suzette A. Pabit, Lois Pollack, David Case

    http://dx.doi.org/10.1063/1.4953037 journal-article Nguyen, H.T. et al., 2016. Extracting water and ion distributions from solution x-ray scattering experiments. The Journal of Chemical Physics, 144(21), p.214105. Available at: http://dx.doi.org/10.1063/1.4953037. Hung T. Nguyen and Suzette A. …

  25. Toward Analysis of Proteins in Single Cells: A Quantitative Approach Employing Isobaric Tags with MALDI Mass Spectrometry Realized with a Microfluidic Platform

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    03 Jun 2016 | BioXFEL Publications | Contributor(s): Mian Yang, Randall Nelson, Alexandra Ros

    http://dx.doi.org/10.1021/acs.analchem.5b03419 journal-article Yang, M., Nelson, R. & Ros, A., 2016. Toward Analysis of Proteins in Single Cells: A Quantitative Approach Employing Isobaric Tags with MALDI Mass Spectrometry Realized with a Microfluidic Platform. Analytical Chemistry, 88(13), …

  26. The Dependence of Carbohydrate–Aromatic Interaction Strengths on the Structure of the Carbohydrate

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    01 Jun 2016 | BioXFEL Publications | Contributor(s): Che-Hsiung Hsu, Sangho Park, David E. Mortenson, B. Lachele Foley, Xiaocong Wang, Robert J. Woods, David Case, Evan T. Powers, Chi-Huey Wong, H. Jane Dyson, Jeffery W. Kelly

    http://dx.doi.org/10.1021/jacs.6b02879 journal-article Hsu, C.-H. et al., 2016. The Dependence of Carbohydrate–Aromatic Interaction Strengths on the Structure of the Carbohydrate. Journal of the American Chemical Society, 138(24), pp.7636–7648. Available at: …

  27. Understanding nucleic acid structural changes by comparing wide-angle x-ray scattering (WAXS) experiments to molecular dynamics simulations

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    25 May 2016 | BioXFEL Publications | Contributor(s): Suzette A. Pabit, Andrea Katz, Igor S. Tolokh, Aleksander Drozdetski, Nathan Baker, Alexey V. Onufriev, Lois Pollack

    http://dx.doi.org/10.1063/1.4950814 journal-article Pabit, S.A. et al., 2016. Understanding nucleic acid structural changes by comparing wide-angle x-ray scattering (WAXS) experiments to molecular dynamics simulations. The Journal of Chemical Physics, 144(20), p.205102. Available at: …

  28. OnDA: online data analysis and feedback for serial X-ray imaging

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    24 May 2016 | BioXFEL Publications | Contributor(s): Valerio Mariani, Andrew Morgan, Chun Hong Yoon, Thomas J. Lane, Thomas A. White, Christopher O'Grady, Manuela Kuhn, Steve Aplin, Jason Koglin, Anton Barty, Henry Chapman

    This article describes a free and open-source data analysis utility designed for fast online feedback during serial X-ray diffraction and scattering experiments:OnDA(online data analysis). Three complete real-time monitors for common types of serial X-ray imaging experiments are presented. These …

  29. Liquid explosions induced by X-ray laser pulses

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    24 May 2016 | BioXFEL Publications | Contributor(s): Claudiu A. Stan, Despina Milathianaki, Hartawan Laksmono, Raymond G. Sierra, Trevor A. McQueen, Marc Messerschmidt, Garth J. Williams, Jason E. Koglin, Thomas J. Lane, Matt J. Hayes, Serge A. H. Guillet, Mengning Liang, Andrew L. Aquila, Philip R. Willmott, Joseph S. Robinson, Karl L. Gumerlock, Sabine Botha, Karol Nass, Ilme Schlichting, Robert L. Shoeman, Howard A. Stone, Sébastien Boutet

    http://dx.doi.org/10.1038/nphys3779 Claudiu A. Stan and Despina Milathianaki and Hartawan Laksmono and Raymond G. Sierra and Trevor A. McQueen and Marc Messerschmidt and Garth J. Williams and Jason E. Koglin and Thomas J. Lane and Matt J. Hayes and Serge A. H. Guillet and Mengning Liang and …

  30. Preprints for the life sciences

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    20 May 2016 | BioXFEL Publications | Contributor(s): J. M. Berg, N. Bhalla, P. E. Bourne, M. Chalfie, D. G. Drubin, J. S. Fraser, C. W. Greider, M. Hendricks, C. Jones, R. Kiley, S. King, M. W. Kirschner, H. M. Krumholz, R. Lehmann, M. Leptin, B. Pulverer, B. Rosenzweig, J. E. Spiro, M. Stebbins, C. Strasser, S. Swaminathan, P. Turner, R. D. Vale, K. VijayRaghavan, C. Wolberger

    http://dx.doi.org/10.1126/science.aaf9133 journal-article Berg, J.M. et al., 2016. Preprints for the life sciences. Science, 352(6288), pp.899–901. Available at: http://dx.doi.org/10.1126/science.aaf9133. J. M. Berg and N. Bhalla and P. E. Bourne and M. Chalfie and D. G. Drubin and J. S. …

  31. Expression and purification of an engineered human endothelin receptor B in a monomeric form

    0.0 out of 5 stars 

    19 May 2016 | BioXFEL Publications | Contributor(s): A. V. Mishin, A. P. Luginina, A. P. Potapenko, V. I. Borshchevskiy, V. Katritch, E. Edelweiss, I. S. Okhrimenko, V. I. Gordeliy, V. G. Cherezov

    journal-article http://dx.doi.org/10.1134/s1607672916020216 Mishin, A.V. et al., 2016. Expression and purification of an engineered human endothelin receptor B in a monomeric form. Doklady Biochemistry and Biophysics, 467(1), pp.157–161. Available at: …

  32. Three-dimensional-printed gas dynamic virtual nozzles for x-ray laser sample delivery

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    18 May 2016 | BioXFEL Publications | Contributor(s): Garrett Charles Nelson, Richard Kirian, Uwe Weierstall, Nadia Zatsepin, Tomáš Faragó, Tilo Baumbach, Fabian Wilde, Fabian B. P. Niesler, Benjamin Zimmer, Izumi Ishigami, Masahide Hikita, Saša Bajt, Syun-Ru Yeh, Denis L. Rousseau, Henry Chapman, John Spence, Michael Heymann

    http://dx.doi.org/10.1364/oe.24.011515 Garrett Nelson and Richard A. Kirian and Uwe Weierstall and Nadia A. Zatsepin and Tomáš Faragó and Tilo Baumbach and Fabian Wilde and Fabian B. P. Niesler and Benjamin Zimmer and Izumi Ishigami and Masahide Hikita and Saša Bajt and Syun-Ru Yeh and Denis L. …

  33. Imaging of Objects by Coherent Diffraction of X-Ray Free-Electron Laser Pulses

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    12 May 2016 | BioXFEL Publications | Contributor(s): Richard Kirian, Henry Chapman

    http://dx.doi.org/10.1007/978-3-319-14394-1_27 Richard A. Kirian and Henry N. Chapman Kirian, R.A. & Chapman, H.N., 2016. Imaging of Objects by Coherent Diffraction of X-Ray Free-Electron Laser Pulses. Synchrotron Light Sources and Free-Electron Lasers, pp.1135–1195. Available at: …

  34. Characterization of protein nanocrystals based on the reversibility of crystallization

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    10 May 2016 | BioXFEL Publications | Contributor(s): Katerina Dörner, Jose M. Martin-Garcia, Christopher Kupitz, Zhen Gong, T. Conn Mallet, Liqing Chen, Rebekka M. Wachter, Petra Fromme

    http://dx.doi.org/10.1021/acs.cgd.6b00384 Katerina Dörner and Jose M. Martin-Garcia and Christopher Kupitz and Zhen Gong and T. Conn Mallet and Liqing Chen and Rebekka M. Wachter and Petra Fromme Dörner, K. et al., 2016. Characterization of Protein Nanocrystals Based on the Reversibility of …

  35. Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein

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    05 May 2016 | BioXFEL Publications | Contributor(s): K. Pande, C. D. M. Hutchison, G. Groenhof, A. Aquila, J. S. Robinson, J. Tenboer, S. Basu, S. Boutet, D. P. DePonte, M. Liang, T. A. White, N. A. Zatsepin, O. Yefanov, D. Morozov, D. Oberthuer, C. Gati, G. Subramanian, D. James, Y. Zhao, J. Koralek, J. Brayshaw, C. Kupitz, C. Conrad, S. Roy-Chowdhury, J. D. Coe, M. Metz, P. L. Xavier, T. D. Grant, J. E. Koglin, G. Ketawala, R. Fromme, V.  rajer, R. Henning, J. C. H. Spence, A. Ourmazd, P. Schwander, U. Weierstall, M. Frank, P. Fromme, A. Barty, H. N. Chapman, K. Moffat, J. J. Van Thor, M. Schmidt

    http://dx.doi.org/10.1126/science.aad5081 K. Pande and C. D. M. Hutchison and G. Groenhof and A. Aquila and J. S. Robinson and J. Tenboer and S. Basu and S. Boutet and D. P. DePonte and M. Liang and T. A. White and N. A. Zatsepin and O. Yefanov and D. Morozov and D. Oberthuer and C. Gati and G. …

  36. Deterministic Absolute Negative Mobility for Micro- and Submicrometer Particles Induced in a Microfluidic Device

    0.0 out of 5 stars 

    05 May 2016 | BioXFEL Publications | Contributor(s): Jinghui Luo, Katherine A. Muratore, Edgar A. Arriaga, Alexandra Ros

    http://dx.doi.org/10.1021/acs.analchem.6b00837 Jinghui Luo and Katherine A. Muratore and Edgar A. Arriaga and Alexandra Ros Luo, J. et al., 2016. Deterministic Absolute Negative Mobility for Micro- and Submicrometer Particles Induced in a Microfluidic Device. Analytical Chemistry, 88(11), …

  37. Review: Serial femtosecond crystallography: A revolution in structural biology

    0.0 out of 5 stars 

    01 May 2016 | BioXFEL Publications | Contributor(s): Jose M. Martin-Garcia, Chelsie E Conrad, Jesse David Coe, Shatabdi Roy-Chowdhury, Petra Fromme

    http://dx.doi.org/10.1016/j.abb.2016.03.036 Jose M. Martin-Garcia and Chelsie E. Conrad and Jesse Coe and Shatabdi Roy-Chowdhury and Petra Fromme Martin-Garcia, J.M. et al., 2016. Serial femtosecond crystallography: A revolution in structural biology. Archives of Biochemistry and Biophysics, 602, …

  38. Photocycle Populations with Femtosecond Excitation of Crystalline Photoactive Yellow Protein

    0.0 out of 5 stars 

    01 May 2016 | BioXFEL Publications | Contributor(s): Christopher D.M. Hutchison, Marius Kaucikas, Jason Tenboer, Christopher Kupitz, Keith Moffat, Marius Schmidt, Jasper J. Van Thor

    http://dx.doi.org/10.1016/j.cplett.2016.04.087 Christopher D.M. Hutchison and Marius Kaucikas and Jason Tenboer and Christopher Kupitz and Keith Moffat and Marius Schmidt and Jasper J. van Thor Hutchison, C.D.M. et al., 2016. Photocycle populations with femtosecond excitation of crystalline …

  39. Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate

    0.0 out of 5 stars 

    29 Apr 2016 | BioXFEL Publications | Contributor(s): Hongnan Cao, Kemin Tan, Fengbin Wang, Lance Bigelow, Ragothaman M. Yennamalli, Robert Jedrzejczak, Gyorgy Babnigg, Craig A. Bingman, Andrzej Joachimiak, Madan K. Kharel, Shanteri Singh, Jon S. Thorson, George Phillips

    http://dx.doi.org/10.1063/1.4948539 journal-article Cao, H. et al., 2016. Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate. Structural Dynamics, 3(3), p.034702. Available at: …

  40. Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta

    0.0 out of 5 stars 

    27 Apr 2016 | BioXFEL Publications | Contributor(s): Ray Yu-Ruei Wang, Yifan Song, Benjamin Barad, Yifan Cheng, James Fraser, Frank DiMaio

    http://dx.doi.org/10.1101/050286 Cryo-EM has revealed many challenging yet exciting macromolecular assemblies at near-atomic resolution (3-4.5 Angstrom), providing biological phenomena with molecular descriptions. However, at these resolutions accurately positioning individual atoms remains …

  41. Dynamics from noisy data with extreme timing uncertainty

    0.0 out of 5 stars 

    26 Apr 2016 | BioXFEL Publications | Contributor(s): R. Fung, A. Ourmazd, A. M. Hanna, O. Vendrell, S. Ramakrishna, T. Seideman, R. Santra

    http://dx.doi.org/10.1038/nature17627 R. Fung and A. Ourmazd and A. M. Hanna and O. Vendrell and S. Ramakrishna and T. Seideman and R. Santra and A. Ourmazd Fung, R. et al., 2016. Dynamics from noisy data with extreme timing uncertainty. Nature, 532(7600), pp.471–475. Available at: …

  42. Transmission electron microscopy for the evaluation and optimization of crystal growth

    0.0 out of 5 stars 

    26 Apr 2016 | BioXFEL Publications | Contributor(s): Hilary P. Stevenson, Guowu Lin, Christopher Barnes, Ieva Sutkeviciute, Troy Krzysiak, Simon C. Weiss, Shelley Reynolds, Ying Wu, Veeranagu Nagarajan, Alexander M. Makhov, Robert M Lawrence, Emily Lamm, Lisa Clark, Timothy J. Gardella, Brenda Hogue, Craig M. Ogata, Jinwoo Ahn, Angela M. Gronenborn, James F. Conway, Jean-Pierre Vilardaga, Aina E. Cohen, Guillermo Calero

    The crystallization of protein samples remains the most significant challenge in structure determination by X-ray crystallography. Here, the effectiveness of transmission electron microscopy (TEM) analysis to aid in the crystallization of biological macromolecules is demonstrated. It was found that …

  43. Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting

    0.0 out of 5 stars 

    25 Apr 2016 | BioXFEL Publications | Contributor(s): David Mavor, Kyle Barlow, Samuel Thompson, Benjamin A Barad, Alain R Bonny, Clinton L Cario, Garrett Gaskins, Zairan Liu, Laura Deming, Seth D Axen, Elena Caceres, Weilin Chen, Adolfo Cuesta, Rachel E Gate, Evan M Green, Kaitlin R Hulce, Weiyue Ji, Lillian R Kenner, Bruk Mensa, Leanna S Morinishi, Steven M Moss, Marco Mravic, Ryan K Muir, Stefan Niekamp, Chimno I Nnadi, Eugene Palovcak, Erin M Poss, Tyler D Ross, Eugenia C Salcedo, Stephanie K See, Meena Subramaniam, Allison W Wong, Jennifer Li, Kurt S Thorn, Shane Ó Conchúir, Benjamin P Roscoe, Eric D Chow, Joseph L DeRisi, Tanja Kortemme, Daniel N Bolon, James Fraser

    Ubiquitin is essential for eukaryotic life and varies in only 3 amino acid positions between yeast and humans. However, recent deep sequencing studies indicate that ubiquitin is highly tolerant to single mutations. We hypothesized that this tolerance would be reduced by chemically induced …

  44. Multi-shell model of ion-induced nucleic acid condensation

    0.0 out of 5 stars 

    21 Apr 2016 | BioXFEL Publications | Contributor(s): Igor S. Tolokh, Aleksander V. Drozdetski, Lois Pollack, Nathan A. Baker, Alexey V. Onufriev

    http://dx.doi.org/10.1063/1.4945382 journal-article Tolokh, I.S. et al., 2016. Multi-shell model of ion-induced nucleic acid condensation. The Journal of Chemical Physics, 144(15), p.155101. Available at: http://dx.doi.org/10.1063/1.4945382. Igor S. Tolokh and Aleksander V. Drozdetski and Lois …

  45. June 2016 Site Visit Agenda

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    21 Apr 2016 | Downloads

    …

  46. SAXS studies of RNA: structures, dynamics, and interactions with partners

    0.0 out of 5 stars 

    12 Apr 2016 | BioXFEL Publications | Contributor(s): Yujie Chen, Lois Pollack

    http://dx.doi.org/10.1002/wrna.1349 Yujie Chen and Lois Pollack Chen, Y. & Pollack, L., 2016. SAXS studies of RNA: structures, dynamics, and interactions with partners. WIREs RNA. Available at: http://dx.doi.org/10.1002/wrna.1349. NSF-STC Biology with X-ray Lasers (NSF-1231306) journal-article

  47. X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex

    0.0 out of 5 stars 

    11 Apr 2016 | BioXFEL Publications | Contributor(s): X. Edward Zhou, Xiang Gao, Anton Barty, Yanyong Kang, Yuanzheng He, Wei Liu, Andrii Ishchenko, Thomas A. White, Oleksandr Yefanov, Gye Won Han, Qingping Xu, Parker W. De Waal, Kelly M. Suino-Powell, Sébastien Boutet, Garth J. Williams, Meitian Wang, Dianfan Li, Martin Caffrey, Henry Chapman, John Spence, Petra Fromme, Uwe Weierstall, Raymond C. Stevens, Vadim Cherezov, Karsten Melcher, H. Eric Xu

    http://dx.doi.org/10.1038/sdata.2016.21 X. Edward Zhou and Xiang Gao and Anton Barty and Yanyong Kang and Yuanzheng He and Wei Liu and Andrii Ishchenko and Thomas A. White and Oleksandr Yefanov and Gye Won Han and Qingping Xu and Parker W. de Waal and Kelly M. Suino-Powell and Sébastien Boutet and …

  48. Synthesis of Water-Soluble, Thiolate-Protected Gold Nanoparticles Uniform in Size

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    04 Apr 2016 | BioXFEL Publications | Contributor(s): Maia Azubel, Roger Kornberg

    journal-article http://dx.doi.org/10.1021/acs.nanolett.6b00981 Azubel, M. & Kornberg, R.D., 2016. Synthesis of Water-Soluble, Thiolate-Protected Gold Nanoparticles Uniform in Size. Nano Letters, 16(5), pp.3348–3351. Available at: http://dx.doi.org/10.1021/acs.nanolett.6b00981. Maia Azubel and …

  49. Protein–DNA and ion–DNA interactions revealed through contrast variation SAXS

    0.0 out of 5 stars 

    02 Apr 2016 | BioXFEL Publications | Contributor(s): Joshua M. Tokuda, Suzette A. Pabit, Lois Pollack

    http://dx.doi.org/10.1007/s12551-016-0196-8 journal-article Tokuda, J.M., Pabit, S.A. & Pollack, L., 2016. Protein–DNA and ion–DNA interactions revealed through contrast variation SAXS. Biophysical Reviews, 8(2), pp.139–149. Available at: http://dx.doi.org/10.1007/s12551-016-0196-8. Joshua …

  50. Melatonin Receptors as Modulators of Methamphetamine-Mediated Behaviors

    0.0 out of 5 stars 

    01 Apr 2016 | BioXFEL Publications | Contributor(s): Shannon J. Clough, Anthony J. Hutchinson, Margarita L. Dubocovich

    http://dx.doi.org/10.1016/b978-0-12-800212-4.00016-9 book-chapter Clough, S.J., Hutchinson, A.J. & Dubocovich, M.L., 2016. Melatonin Receptors as Modulators of Methamphetamine-Mediated Behaviors. Neuropathology of Drug Addictions and Substance Misuse, pp.169–180. Available at: …

  51. 2016 Serial Crystallography Data Analysis Workshop at ACA Annual Meeting.

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    31 Mar 2016 | Workshops

    We are running a serial femtosecond crystallography data analysis workshop at ACA 2016 in Denver, CO, focused on "Serial Crystallography Data Analysis with Cheetah and CrystFEL: Concepts and Tutorials".  ACA 2016 Workshop Site   Workshop format: The workshop will start with an introductory …

  52. Recent developments in CrystFEL

    0.0 out of 5 stars 

    29 Mar 2016 | BioXFEL Publications | Contributor(s): Thomas A. White, Valerio Mariani, Wolfgang Brehm, Oleksandr Yefanov, Anton Barty, Kenneth R. Beyerlein, Fedor Chervinskii, Lorenzo Galli, Cornelius Gati, Takanori Nakane, Alexandra Tolstikova, Keitaro Yamashita, Chun Hong Yoon, Kay Diederichs, Henry Chapman

    CrystFELis a suite of programs for processing data from `serial crystallography' experiments, which are usually performed using X-ray free-electron lasers (FELs) but also increasingly with other X-ray sources. TheCrystFELsoftware suite has been under development since 2009, just before the first …

  53. Measuring and modeling diffuse scattering in protein X-ray crystallography

    0.0 out of 5 stars 

    28 Mar 2016 | BioXFEL Publications | Contributor(s): Andrew H. Van Benschoten, Lin Liu, Ana Gonzalez, Aaron S. Brewster, Nicholas K. Sauter, James Fraser, Michael E. Wall

    http://dx.doi.org/10.1073/pnas.1524048113 Andrew H. Van Benschoten and Lin Liu and Ana Gonzalez and Aaron S. Brewster and Nicholas K. Sauter and James S. Fraser and Michael E. Wall Van Benschoten, A.H. et al., 2016. Measuring and modeling diffuse scattering in protein X-ray crystallography. …

  54. Expression and Association of the Yersinia pestis Translocon Proteins, YopB and YopD, Are Facilitated by Nanolipoprotein Particles

    0.0 out of 5 stars 

    25 Mar 2016 | BioXFEL Publications | Contributor(s): Matthew Coleman, Jenny A. Cappuccio, Craig D. Blanchette, Tingjuan Gao, Erin S. Arroyo, Angela K. Hinz, Feliza A. Bourguet, Brent W. Segelke, Paul D. Hoeprich, Thomas Huser, Ted A. Laurence, Vladimir L. Motin, Brett A. Chromy

    http://dx.doi.org/10.1371/journal.pone.0150166 Matthew A. Coleman and Jenny A. Cappuccio and Craig D. Blanchette and Tingjuan Gao and Erin S. Arroyo and Angela K. Hinz and Feliza A. Bourguet and Brent Segelke and Paul D. Hoeprich and Thomas Huser and Ted A. Laurence and Vladimir L. Motin and Brett …

  55. Immunological Characterization of Plant-Based HIV-1 Gag/Dgp41 Virus-Like Particles

    0.0 out of 5 stars 

    17 Mar 2016 | BioXFEL Publications | Contributor(s): Sarah A. Kessans, Mark D. Linhart, Lydia R. Meador, Jacquelyn Kilbourne, Brenda Hogue, Petra Fromme, Nobuyuki Matoba, Tsafrir S. Mor

    http://dx.doi.org/10.1371/journal.pone.0151842 Sarah A. Kessans and Mark D. Linhart and Lydia R. Meador and Jacquelyn Kilbourne and Brenda G. Hogue and Petra Fromme and Nobuyuki Matoba and Tsafrir S. Mor Kessans, S.A. et al., 2016. Immunological Characterization of Plant-Based HIV-1 Gag/Dgp41 …

  56. Visualizing aerosol-particle injection for diffractive-imaging experiments

    0.0 out of 5 stars 

    16 Mar 2016 | BioXFEL Publications | Contributor(s): Salah Awel, Richard Kirian, Niko Eckerskorn, Max Oliver Wiedorn, Daniel A. Horke, Andrei V. Rode, Jochen Küpper, Henry Chapman

    http://dx.doi.org/10.1364/oe.24.006507 Salah Awel and Richard A. Kirian and Niko Eckerskorn and Max Wiedorn and Daniel A. Horke and Andrei V. Rode and Jochen Küpper and Henry N. Chapman Awel, S. et al., 2016. Visualizing aerosol-particle injection for diffractive-imaging experiments. Optics …

  57. Anomalous Nonlinear X-ray Compton Scattering

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    14 Mar 2016 | BioXFEL Publications | Contributor(s): Matthias Fuchs

    proceedings-article http://dx.doi.org/10.1364/hilas.2016.hm3b.1 Fuchs, M., 2016. Anomalous Nonlinear X-ray Compton Scattering. High-Brightness Sources and Light-Driven Interactions. Available at: http://dx.doi.org/10.1364/hilas.2016.hm3b.1. Matthias Fuchs

  58. Data publication with the structural biology data grid supports live analysis

    0.0 out of 5 stars 

    07 Mar 2016 | BioXFEL Publications | Contributor(s): Peter A. Meyer, Stephanie Socias, Jason Key, Elizabeth Ransey, Emily C. Tjon, Alejandro Buschiazzo, Ming Lei, Chris Botka, James Withrow, David Neau, Kanagalaghatta Rajashankar, Karen S. Anderson, Richard H. Baxter, Stephen C. Blacklow, Titus J. Boggon, Alexandre M. J. J. Bonvin, Dominika Borek, Tom J. Brett, Amedeo Caflisch, Chung-I Chang, Walter J. Chazin, Kevin D. Corbett, Michael S. Cosgrove, Sean Crosson, Sirano Dhe-Paganon, Enrico Di Cera, Catherine L. Drennan, Michael J. Eck, Brandt F. Eichman, Qing R. Fan, Adrian R. Ferré-D'Amaré, J. Christopher Fromme, K. Christopher Garcia, Rachelle Gaudet, Peng Gong, Stephen C. Harrison, Ekaterina E. Heldwein, Zongchao Jia, Robert J. Keenan, Andrew C. Kruse, Marc Kvansakul, Jason S. McLellan, Yorgo Modis, Yunsun Nam, Zbyszek Otwinowski, Emil F. Pai, Pedro José Barbosa Pereira, Carlo Petosa, C. S. Raman, Tom A. Rapoport, Antonina Roll-Mecak, Michael K. Rosen, Gabby Rudenko, Joseph Schlessinger, Thomas U. Schwartz, Yousif Shamoo, Holger Sondermann, Yizhi J. Tao, Niraj H. Tolia, Oleg V. Tsodikov, Kenneth D. Westover, Hao Wu, Ian Foster, James Fraser, Filipe R. N C. Maia, Tamir Gonen, Tom Kirchhausen, Kay Diederichs, Mercè Crosas, Piotr Sliz

    journal-article http://dx.doi.org/10.1038/ncomms10882 Meyer, P.A. et al., 2016. Data publication with the structural biology data grid supports live analysis. Nature Communications, 7, p.10882. Available at: http://dx.doi.org/10.1038/ncomms10882. Peter A. Meyer and Stephanie Socias and Jason Key …

  59. Assessment of microcrystal quality by transmission electron microscopy for efficient serial femtosecond crystallography

    0.0 out of 5 stars 

    02 Mar 2016 | BioXFEL Publications | Contributor(s): Christopher Barnes, Elena G. Kovaleva, Xiaofeng Fu, Hilary P. Stevenson, Aaron S. Brewster, Daniel P. DePonte, Elizabeth L. Baxter, Aina E. Cohen, Guillermo Calero

    journal-article http://dx.doi.org/10.1016/j.abb.2016.02.011 Barnes, C.O. et al., 2016. Assessment of microcrystal quality by transmission electron microscopy for efficient serial femtosecond crystallography. Archives of Biochemistry and Biophysics, 602, pp.61–68. Available at: …

  60. AXSIS: Exploring the frontiers in attosecond X-ray science, imaging and spectroscopy

    0.0 out of 5 stars 

    28 Feb 2016 | BioXFEL Publications | Contributor(s): F.X. Kärtner, F. Ahr, A.-L. Calendron, H. Çankaya, S. Carbajo, G. Chang, G. Cirmi, K. Dörner, U. Dorda, A. Fallahi, A. Hartin, M. Hemmer, R. Hobbs, Y. Hua, W.R. Huang, R. Letrun, N. Matlis, V. Mazalova, O.D. Mücke, E. Nanni, W. Putnam, K. Ravi, F. Reichert, I. Sarrou, X. Wu, A. Yahaghi, H. Ye, L. Zapata, D. Zhang, C. Zhou, R.J.D. Miller, K.K. Berggren, H. Graafsma, A. Meents, R.W. Assmann, H.N. Chapman, P. Fromme

    http://dx.doi.org/10.1016/j.nima.2016.02.080 F.X. Kärtner and F. Ahr and A.-L. Calendron and H. Çankaya and S. Carbajo and G. Chang and G. Cirmi and K. Dörner and U. Dorda and A. Fallahi and A. Hartin and M. Hemmer and R. Hobbs and Y. Hua and W.R. Huang and R. Letrun and N. Matlis and V. …

  61. Protein Crystallization in an Actuated Microfluidic Nanowell Device

    0.0 out of 5 stars 

    25 Feb 2016 | BioXFEL Publications | Contributor(s): Bahige G. Abdallah, Shatabdi Roy-Chowdhury, Raimund Fromme, Petra Fromme, Alexandra Ros

    http://dx.doi.org/10.1021/acs.cgd.5b01748 Bahige G. Abdallah and Shatabdi Roy-Chowdhury and Raimund Fromme and Petra Fromme and Alexandra Ros Abdallah, B.G. et al., 2016. Protein Crystallization in an Actuated Microfluidic Nanowell Device. Crystal Growth & Design. Available at: …

  62. Polyclonal Antibody Production for Membrane Proteins via Genetic Immunization

    0.0 out of 5 stars 

    24 Feb 2016 | BioXFEL Publications | Contributor(s): Debra T. Hansen, Mark D. Robida, Felicia M. Craciunescu, Andrey V. Loskutov, Katerina Dörner, John-Charles Rodenberry, Xiao Wang, Tien L. Olson, Hetal Patel, Petra Fromme, Kathryn F. Sykes

    http://dx.doi.org/10.1038/srep21925 Debra T. Hansen and Mark D. Robida and Felicia M. Craciunescu and Andrey V. Loskutov and Katerina Dörner and John-Charles Rodenberry and Xiao Wang and Tien L. Olson and Hetal Patel and Petra Fromme and Kathryn F. Sykes Hansen, D.T. et al., 2016. Polyclonal …

  63. Reconstructing three-dimensional helical structure with an X-ray free electron laser

    0.0 out of 5 stars 

    23 Feb 2016 | BioXFEL Publications | Contributor(s): M. Uddin

    Recovery of three-dimensional structure from single-particle X-ray scattering of completely randomly oriented diffraction patterns as predicted a few decades ago has been realized owing to the advent of the new emerging X-ray free electron laser (XFEL) technology. Since the world's first XFEL …

  64. Loop dynamics of thymidine diphosphate-rhamnose 3′-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis

    0.0 out of 5 stars 

    18 Feb 2016 | BioXFEL Publications | Contributor(s): Lu Han, Shanteri Singh, Jon S. Thorson, George Phillips

    http://dx.doi.org/10.1063/1.4941368 Lu Han and Shanteri Singh and Jon S. Thorson and George N. Phillips Han, L. et al., 2016. Loop dynamics of thymidine diphosphate-rhamnose 3′-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis. Structural Dynamics, 3(1), p.012004. Available …

  65. The Structural History of RNA Polymerase Transcription Machinery

    0.0 out of 5 stars 

    18 Feb 2016 | Teaching Materials | Contributor(s): Roger Kornberg

    Dr. Roger Kornberg, 2006 Nobel Laureate in Chemistry, discusses the structural history of the RNA polymerase II transcription machinery and how it played a role in his successful career.

  66. Structural Studies of the Human Kappa Opioid Receptor Active State Conformations

    0.0 out of 5 stars 

    16 Feb 2016 | BioXFEL Publications | Contributor(s): Ming-Yue Lee, Nilkanth N Patel, Vsevolod Katritch, Raymond C. Stevens, Vadim Cherezov

    http://dx.doi.org/10.1016/j.bpj.2015.11.275 Ming-Yue Lee and Nilkanth Patel and Vsevolod Katritch and Raymond C. Stevens and Vadim Cherezov Lee, M.-Y. et al., 2016. Structural Studies of the Human Kappa Opioid Receptor Active State Conformations. Biophysical Journal, 110(3), p.38a–39a. Available …

  67. An in Vitro Investigation of Globin Folding and Expression

    0.0 out of 5 stars 

    16 Feb 2016 | BioXFEL Publications | Contributor(s): Premila P. Samuel, William Ou, George Phillips, John S. Olson

    http://dx.doi.org/10.1016/j.bpj.2015.11.1166 journal-article Samuel, P.P. et al., 2016. An in Vitro Investigation of Globin Folding and Expression. Biophysical Journal, 110(3), p.209a–210a. Available at: http://dx.doi.org/10.1016/j.bpj.2015.11.1166. Premila P. Samuel and William Ou and George …

  68. Preparation and Delivery of Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography

    0.0 out of 5 stars 

    16 Feb 2016 | BioXFEL Publications | Contributor(s): Andrii Ishchenko, Vadim Cherezov, Wei Liu

    http://dx.doi.org/10.1016/j.bpj.2015.11.383 Andrii Ishchenko and Vadim Cherezov and Wei Liu Ishchenko, A., Cherezov, V. & Liu, W., 2016. Preparation and Delivery of Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography. Biophysical Journal, 110(3), p.59a. Available at: …

  69. Continuous Changes in Structure Mapped by Manifold Embedding of Single-Particle Data in Cryo-EM

    0.0 out of 5 stars 

    14 Feb 2016 | BioXFEL Publications | Contributor(s): Joachim Frank, Abbas Ourmazd

    http://dx.doi.org/10.1016/j.ymeth.2016.02.007 Joachim Frank and Abbas Ourmazd Frank, J. & Ourmazd, A., 2016. Continuous Changes in Structure Mapped by Manifold Embedding of Single-Particle Data in Cryo-EM. Methods. Available at: http://dx.doi.org/10.1016/j.ymeth.2016.02.007. NSF-STC Biology with …

  70. Macromolecular diffractive imaging using imperfect crystals

    0.0 out of 5 stars 

    10 Feb 2016 | BioXFEL Publications | Contributor(s): Kartik Ayyer, Oleksandr M. Yefanov, Dominik Oberthür, Shatabdi Roy-Chowdhury, Lorenzo Galli, Valerio Mariani, Shibom Basu, Jesse David Coe, Chelsie E Conrad, Raimund Fromme, Alexander Schaffer, Katerina Dörner, Daniel James, Christopher Kupitz, Markus Metz, Garrett Charles Nelson, Paulraj Lourdu Xavier, Kenneth R. Beyerlein, Marius Schmidt, Iosifina Sarrou, John Spence, Uwe Weierstall, Thomas A. White, Jay-How Yang, Yun Zhao, Mengning Liang, Andrew Aquila, Mark S. Hunter, Joseph S. Robinson, Jason E. Koglin, Sébastien Boutet, Petra Fromme, Anton Barty, Henry Chapman

    http://dx.doi.org/10.1038/nature16949 Kartik Ayyer and Oleksandr M. Yefanov and Dominik Oberthür and Shatabdi Roy-Chowdhury and Lorenzo Galli and Valerio Mariani and Shibom Basu and Jesse Coe and Chelsie E. Conrad and Raimund Fromme and Alexander Schaffer and Katerina Dörner and Daniel James and …

  71. Concentration of Sindbis virus with optimized gradient insulator-based dielectrophoresis

    0.0 out of 5 stars 

    08 Feb 2016 | BioXFEL Publications | Contributor(s): Jie Ding, Robert M Lawrence, Paul V. Jones, Brenda Hogue, Mark A. Hayes

    http://dx.doi.org/10.1039/c5an02430g Jie Ding and Robert M. Lawrence and Paul V. Jones and Brenda G. Hogue and Mark A. Hayes Ding, J. et al., 2016. Concentration of Sindbis virus with optimized gradient insulator-based dielectrophoresis. Analyst. Available at: http://dx.doi.org/10.1039/c5an02430g. …

  72. CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites

    0.0 out of 5 stars 

    05 Feb 2016 | BioXFEL Publications | Contributor(s): Peter Cimermancic, Patrick Weinkam, T. Justin Rettenmaier, Leon Bichmann, Daniel A. Keedy, Rahel Woldeyes, Dina Schneidman-Duhovny, Omar N. Demerdash, Julie C. Mitchell, James A. Wells, James Fraser, Andrej Sali

    http://dx.doi.org/10.1016/j.jmb.2016.01.029 Peter Cimermancic and Patrick Weinkam and T. Justin Rettenmaier and Leon Bichmann and Daniel A. Keedy and Rahel A. Woldeyes and Dina Schneidman-Duhovny and Omar N. Demerdash and Julie C. Mitchell and James A. Wells and James S. Fraser and Andrej Sali …

  73. Transient lattice contraction in the solid-to-plasma transition

    0.0 out of 5 stars 

    29 Jan 2016 | BioXFEL Publications | Contributor(s): Ken R. Ferguson, Maximilian Bucher, Tais Gorkhover, Sébastien Boutet, Hironobu Fukuzawa, Jason E. Koglin, Yoshiaki Kumagai, Alberto Lutman, Agostino Marinelli, Marc Messerschmidt, Kiyonobu Nagaya, Jim Turner, Kiyoshi Ueda, Garth J. Williams, Philip H. Bucksbaum, Christoph Bostedt

    http://dx.doi.org/10.1126/sciadv.1500837 Ken R. Ferguson and Maximilian Bucher and Tais Gorkhover and Sébastien Boutet and Hironobu Fukuzawa and Jason E. Koglin and Yoshiaki Kumagai and Alberto Lutman and Agostino Marinelli and Marc Messerschmidt and Kiyonobu Nagaya and Jim Turner and Kiyoshi Ueda …

  74. One dimensional focusing with high numerical aperture multilayer Laue lens

    0.0 out of 5 stars 

    28 Jan 2016 | BioXFEL Publications | Contributor(s): Saša Bajt, Mauro Prasciolu, Andrew J. Morgan, Henry Chapman, Jacek Krzywinski, Andrzej Andrejczuk

    http://dx.doi.org/10.1063/1.4937543 Saša Bajt and Mauro Prasciolu and Andrew J. Morgan and Henry N. Chapman and Jacek Krzywinski and Andrzej Andrejczuk Bajt, S. et al., 2016. One dimensional focusing with high numerical aperture multilayer Laue lens. Available at: …

  75. Imaging of Objects by Coherent Diffraction of X-Ray Free-Electron Laser Pulses

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    28 Jan 2016 | BioXFEL Publications | Contributor(s): Richard Kirian, Henry Chapman

    http://dx.doi.org/10.1007/978-3-319-04507-8_27-2 Richard A. Kirian and Henry N. Chapman Kirian, R.A. & Chapman, H.N., 2015. Imaging of Objects by Coherent Diffraction of X-Ray Free-Electron Laser Pulses. Synchrotron Light Sources and Free-Electron Lasers, pp.1–55. Available at: …

  76. Femtosecond and nanometre visualization of structural dynamics in superheated nanoparticles

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    25 Jan 2016 | BioXFEL Publications | Contributor(s): Tais Gorkhover, Sebastian Schorb, Ryan Coffee, Marcus Adolph, Lutz Foucar, Daniela Rupp, Andrew Aquila, John D. Bozek, Sascha W. Epp, Benjamin Erk, Lars Gumprecht, Lotte Holmegaard, Andreas Hartmann, Robert Hartmann, Günter Hauser, Peter Holl, Andre Hömke, Per Johnsson, Nils Kimmel, Kai-Uwe Kühnel, Marc Messerschmidt, Christian Reich, Arnaud Rouzée, Benedikt Rudek, Carlo Schmidt, Joachim Schulz, Heike Soltau, Stephan Stern, Georg Weidenspointner, Bill White, Jochen Küpper, Lothar Strüder, Ilme Schlichting, Joachim Ullrich, Daniel Rolles, Artem Rudenko, Thomas Möller, Christoph Bostedt

    http://dx.doi.org/10.1038/nphoton.2015.264 Tais Gorkhover and Sebastian Schorb and Ryan Coffee and Marcus Adolph and Lutz Foucar and Daniela Rupp and Andrew Aquila and John D. Bozek and Sascha W. Epp and Benjamin Erk and Lars Gumprecht and Lotte Holmegaard and Andreas Hartmann and Robert Hartmann …

  77. Melatonin receptor activation increases glutamatergic synaptic transmission in the rat medial lateral habenula

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    22 Jan 2016 | BioXFEL Publications | Contributor(s): Katherine M. Evely, Randall L. Hudson, Margarita L. Dubocovich, Samir Haj-dahmane

    http://dx.doi.org/10.1002/syn.21892 journal-article Evely, K.M. et al., 2016. Melatonin receptor activation increases glutamatergic synaptic transmission in the rat medial lateral habenula. Synapse, 70(5), pp.181–186. Available at: http://dx.doi.org/10.1002/syn.21892. Katherine M. Evely and …

  78. Serial femtosecond crystallography opens new avenues for Structural Biology

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    20 Jan 2016 | BioXFEL Publications | Contributor(s): Jesse David Coe, Petra Fromme

    http://dx.doi.org/10.2174/0929866523666160120152937 Jesse Coe and Petra Fromme Coe, J. & Fromme, P., 2016. Serial femtosecond crystallography opens new avenues for Structural Biology. PPL, 23(3), pp.255–272. Available at: http://dx.doi.org/10.2174/0929866523666160120152937. NSF-STC Biology with …

  79. The Role of Correlation and Solvation in Ion Interactions with B-DNA

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    19 Jan 2016 | BioXFEL Publications | Contributor(s): Maria L. Sushko, Dennis G. Thomas, Suzette A. Pabit, Lois Pollack, Alexey V. Onufriev, Nathan A. Baker

    journal-article http://dx.doi.org/10.1016/j.bpj.2015.12.011 Sushko, M.L. et al., 2016. The Role of Correlation and Solvation in Ion Interactions with B-DNA. Biophysical Journal, 110(2), pp.315–326. Available at: http://dx.doi.org/10.1016/j.bpj.2015.12.011. Maria L. Sushko and Dennis G. Thomas …

  80. In cellulo serial crystallography of alcohol oxidase crystals inside yeast cells

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    11 Jan 2016 | BioXFEL Publications | Contributor(s): Arjen J. Jakobi, Daniel M. Passon, Kèvin Knoops, Francesco Stellato, Mengning Liang, Thomas A. White, Thomas Seine, Marc Messerschmidt, Henry Chapman, Matthias Wilmanns

    The possibility of using femtosecond pulses from an X-ray free-electron laser to collect diffraction data from protein crystals formed in their native cellular organelle has been explored. X-ray diffraction of submicrometre-sized alcohol oxidase crystals formed in peroxisomes within cells of …

  81. Computational crystallization

    0.0 out of 5 stars 

    11 Jan 2016 | BioXFEL Publications | Contributor(s): Irem Altan, Patrick Charbonneau, Edward Snell

    http://dx.doi.org/10.1016/j.abb.2016.01.004 Irem Altan and Patrick Charbonneau and Edward H. Snell Altan, I., Charbonneau, P. & Snell, E.H., 2016. Computational crystallization. Archives of Biochemistry and Biophysics. Available at: http://dx.doi.org/10.1016/j.abb.2016.01.004. journal-article

  82. Serial femtosecond crystallography on in vivo grown crystals at SACLA - developments and results

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Leonard M. G. Chavas, Sasa Bajt, Lars Gumprecht, Henry Chapman

    http://dx.doi.org/10.1107/s2053273315097831 Leonard M. G. Chavas and Sasa Bajt and Lars Gumprecht and Henry N. Chapman Chavas, L.M.G. et al., 2015. Serial femtosecond crystallography on in vivo grown crystals at SACLA - developments and results . Acta Cryst Sect A Found Adv, 71(a1), …

  83. Towards a generalised approach for the time-resolved crystallographic study of enzymes

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Diana C. F. Monteiro, Vijay Patel, Christopher P. Bartlett, Shingo Nozaki, Thomas D. Grant, James A. Gowdy, Gary S. Thompson, Arnout P. Kalverda, Edward Snell, Hironori Niki, Arwen R. Pearson, Michael E. Webb

    http://dx.doi.org/10.1107/s205327331509957x Diana C. F. Monteiro and Vijay Patel and Christopher P. Bartlett and Shingo Nozaki and Thomas D. Grant and James A. Gowdy and Gary S. Thompson and Arnout P. Kalverda and Edward H. Snell and Hironori Niki and Arwen R. Pearson and Michael E. Webb Monteiro, …

  84. Phase retrieval for randomly terminated finite crystals

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Joe Chen, Rick A. Kirian, Richard J. Bean, Kenneth R. Beyerlein, Miriam Barthelmess, Chun Hong Yoon, Fenglin Wang, Flavio Capotondi, Emanuele Pedersoli, Anton Barty, Henry Chapman, Philip J. Bones, Romain D. Arnal, Rick P. Millane, John Spence

    http://dx.doi.org/10.1107/s2053273315099714 Joe P. J. Chen and Rick A. Kirian and Richard J. Bean and Kenneth R. Beyerlein and Miriam Barthelmess and Chun Hong Yoon and Fenglin Wang and Flavio Capotondi and Emanuele Pedersoli and Anton Barty and Henry N. Chapman and Philip J. Bones and Romain D. …

  85. Improving resolution in serial crystallography

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Kartik Ayyer, Oleksandr M. Yefanov, Dominik Oberthuer, Shatabdi Roy Chowdhury, Lorenzo Galli, Valerio Mariani, Shibom Basu, Jesse David Coe, Chelsie E Conrad, Raimund Fromme, Katerina Doerner, Matthias Frank, Daniel James, Christopher Kupitz, Markus Metz, Garrett Charles Nelson, Xavier L. Paulraj, Kenneth Beyerlein, Marius Schmidt, Iosifina Sarrou, John Spence, Uwe Weierstall, Thomas A. White, Jayhow Yang, Nadia Zatsepin, Yun Zhao, Mengning Liang, Andrew Aquila, Mark S. Hunter, Joseph S. Robinson, Jason E. Koglin, Sébastien Boutet, Petra Fromme, Anton Barty, Henry Chapman

    http://dx.doi.org/10.1107/s2053273315099738 Kartik Ayyer and Oleksandr M. Yefanov and Dominik Oberthuer and Shatabdi Chowdhury and Lorenzo Galli and Valerio Mariani and Shibom Basu and Jesse Coe and Chelsie E. Conrad and Raimund Fromme and Katerina Doerner and Matthias Frank and Daniel James and …

  86. Serial synchrotron crystallography experiments at EMBL beamline P14 at PETRA III

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Thomas R. Schneider, Gleb Bourenkov, Cornelius Gati, Henry Chapman, Lars Redecke, Ulrich Zander, José A. Marquez, Florent Cipriani

    http://dx.doi.org/10.1107/s2053273315099805 Thomas R. Schneider and Gleb Bourenkov and Cornelius Gati and Henry N. Chapman and Lars Redecke and Ulrich Zander and José A. Marquez and Florent Cipriani and Thomas R. Schneider Schneider, T.R. et al., 2015. Serial synchrotron crystallography …

  87. Interview with Dilano Saldin

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    05 Jan 2016 | Teaching Materials

    Combining data from new facilities with mathematical methods, Professor Dilano Saldin is in pursuit of a technique to determine the structure of molecules without the need for purification or crystallization.

  88. Ternary structure reveals mechanism of a membrane diacylglycerol kinase

    0.0 out of 5 stars 

    17 Dec 2015 | BioXFEL Publications | Contributor(s): Dianfan Li, Phillip J. Stansfeld, Mark S. P. Sansom, Aaron Keogh, Lutz Vogeley, Nicole Howe, Joseph A. Lyons, David Aragao, Petra Fromme, Raimund Fromme, Shibom Basu, Ingo Grotjohann, Christopher Kupitz, Kimberley Rendek, Uwe Weierstall, Nadia Zatsepin, Vadim Cherezov, Wei Liu, Sateesh Bandaru, Niall J. English, Cornelius Gati, Anton Barty, Oleksandr Yefanov, Henry Chapman, Kay Diederichs, Marc Messerschmidt, Sébastien Boutet, Garth J. Williams, M. Marvin Seibert, Martin Caffrey

    http://dx.doi.org/10.1038/ncomms10140 Dianfan Li and Phillip J. Stansfeld and Mark S. P. Sansom and Aaron Keogh and Lutz Vogeley and Nicole Howe and Joseph A. Lyons and David Aragao and Petra Fromme and Raimund Fromme and Shibom Basu and Ingo Grotjohann and Christopher Kupitz and Kimberley Rendek …

  89. Tuning RNA Flexibility with Helix Length and Junction Sequence

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    15 Dec 2015 | BioXFEL Publications | Contributor(s): Julie L. Sutton, Lois Pollack

    http://dx.doi.org/10.1016/j.bpj.2015.10.039 journal-article Sutton, J.L. & Pollack, L., 2015. Tuning RNA Flexibility with Helix Length and Junction Sequence. Biophysical Journal, 109(12), pp.2644–2653. Available at: http://dx.doi.org/10.1016/j.bpj.2015.10.039. Julie L. Sutton and Lois Pollack

  90. Optically Induced Forces Imposed in an Optical Funnel on a Stream of Particles in Air or Vacuum

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    11 Dec 2015 | BioXFEL Publications | Contributor(s): Niko Eckerskorn, Richard Bowman, Richard Kirian, Salah Awel, Max Oliver Wiedorn, Jochen Küpper, Miles J. Padgett, Henry Chapman, Andrei V. Rode

    http://dx.doi.org/10.1103/physrevapplied.4.064001 Niko Eckerskorn and Richard Bowman and Richard A. Kirian and Salah Awel and Max Wiedorn and Jochen Küpper and Miles J. Padgett and Henry N. Chapman and Andrei V. Rode Eckerskorn, N. et al., 2015. Optically Induced Forces Imposed in an Optical …

  91. Time-Resolved Crystallography at X-ray Free Electron Lasers and Synchrotron Light Sources

    0.0 out of 5 stars 

    09 Dec 2015 | BioXFEL Publications | Contributor(s): Marius Schmidt

    http://dx.doi.org/10.1080/08940886.2015.1101324 Marius Schmidt Schmidt, M., 2015. Time-Resolved Crystallography at X-ray Free Electron Lasers and Synchrotron Light Sources. Synchrotron Radiation News, 28(6), pp.25–30. Available at: http://dx.doi.org/10.1080/08940886.2015.1101324. NSF-STC Biology …

  92. Ceramic micro-injection molded nozzles for serial femtosecond crystallography sample delivery

    0.0 out of 5 stars 

    09 Dec 2015 | BioXFEL Publications | Contributor(s): K. R. Beyerlein, L. Adriano, M. Heymann, R. Kirian, J. Knoška, F. Wilde, H. N. Chapman, S. Bajt

    http://dx.doi.org/10.1063/1.4936843 K. R. Beyerlein and L. Adriano and M. Heymann and R. Kirian and J. Knoška and F. Wilde and H. N. Chapman and S. Bajt Beyerlein, K.R. et al., 2015. Ceramic micro-injection molded nozzles for serial femtosecond crystallography sample delivery. Review of Scientific …

  93. Measuring and modeling diffuse scattering in protein X-ray crystallography

    0.0 out of 5 stars 

    07 Dec 2015 | BioXFEL Publications | Contributor(s): Andrew H Van Benschoten, Lin Liu, Ana Gonzalez, Aaron S Brewster, Nicholas K Sauter, James Fraser, Michael Wall

    X-ray diffraction has the potential to provide rich information about the structural dynamics of macromolecules. To realize this potential, both Bragg scattering, which is currently used to derive macromolecular structures, and diffuse scattering, which reports on correlations in charge density …

  94. The Fragment Molecular Orbital Method Reveals New Insight into the Chemical Nature of GPCR–Ligand Interactions

    0.0 out of 5 stars 

    07 Dec 2015 | BioXFEL Publications | Contributor(s): Alexander Heifetz, Ewa I. Chudyk, Laura Gleave, Matteo Aldeghi, Vadim Cherezov, Dmitri G. Fedorov, Philip C. Biggin, Mike J. Bodkin

    http://dx.doi.org/10.1021/acs.jcim.5b00644 Alexander Heifetz and Ewa I. Chudyk and Laura Gleave and Matteo Aldeghi and Vadim Cherezov and Dmitri G. Fedorov and Philip C. Biggin and Mike J. Bodkin Heifetz, A. et al., 2016. The Fragment Molecular Orbital Method Reveals New Insight into the Chemical …

  95. Multitemperature data and diffuse scattering in X-ray crystallography

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    07 Dec 2015 | Teaching Materials | Contributor(s): James Fraser

    Dr. James Fraser will discuss recent advances in mapping the structural basis of protein conformational dynamics using multitemperature data and diffuse scattering from both conventional synchrotron sources and XFELs.

  96. Structural Basis of Stereospecificity in the Bacterial Enzymatic Cleavage of β-Aryl Ether Bonds in Lignin

    0.0 out of 5 stars 

    04 Dec 2015 | BioXFEL Publications | Contributor(s): Kate E. Helmich, Jose Henrique Pereira, Daniel L. Gall, Richard A. Heins, Ryan P. McAndrew, Craig Bingman, Kai Deng, Keefe C. Holland, Daniel R. Noguera, Blake A. Simmons, Kenneth L. Sale, John Ralph, Timothy J. Donohue, Paul D. Adams, George Phillips

    http://dx.doi.org/10.1074/jbc.m115.694307 Kate E. Helmich and Jose Henrique Pereira and Daniel L. Gall and Richard A. Heins and Ryan P. McAndrew and Craig Bingman and Kai Deng and Keefe C. Holland and Daniel R. Noguera and Blake A. Simmons and Kenneth L. Sale and John Ralph and Timothy J. Donohue …

  97. High-density grids for efficient data collection from multiple crystals

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    03 Dec 2015 | BioXFEL Publications | Contributor(s): Elizabeth L. Baxter, Laura Aguila, Roberto Alonso-Mori, Christopher Barnes, Christopher A. Bonagura, Winnie Brehmer, Axel T. Brunger, Guillermo Calero, Tom T. Caradoc-Davies, Ruchira Chatterjee, William F. Degrado, James Fraser, Mohamed Ibrahim, Jan Kern, Brian K. Kobilka, Andrew C. Kruse, Karl M. Larsson, Heinrik T. Lemke, Artem Y. Lyubimov, Aashish Manglik, Scott E. McPhillips, Erik Norgren, Siew S. Pang, S. M. Soltis, Jinhu Song, Jessica Thomaston, Yingssu Tsai, William I. Weis, Rahel Woldeyes, Vittal Yachandra, Junko Yano, Athina Zouni, Aina E. Cohen

    Higher throughput methods to mount and collect data from multiple small and radiation-sensitive crystals are important to support challenging structural investigations using microfocus synchrotron beamlines. Furthermore, efficient sample-delivery methods are essential to carry out productive …

  98. Concentric-flow electrokinetic injector enables serial crystallography of ribosome and photosystem II

    0.0 out of 5 stars 

    30 Nov 2015 | BioXFEL Publications | Contributor(s): Raymond G Sierra, Cornelius Gati, Hartawan Laksmono, E Han Dao, Sheraz Gul, Franklin Fuller, Jan Kern, Ruchira Chatterjee, Mohamed Ibrahim, Aaron S Brewster, Iris Diane Young, Tara Michels-Clark, Andrew Aquila, Mengning Liang, Mark S. Hunter, Jason E Koglin, Sébastien Boutet, Elia A Junco, Brandon Hayes, Michael J Bogan, Christina Y Hampton, Elisabetta V Puglisi, Nicholas K Sauter, Claudiu A Stan, Athina Zouni, Junko Yano, Vittal K Yachandra, S Michael Soltis, Joseph D Puglisi, Hasan Demirci

    http://dx.doi.org/10.1038/nmeth.3667 Raymond G Sierra and Cornelius Gati and Hartawan Laksmono and E Han Dao and Sheraz Gul and Franklin Fuller and Jan Kern and Ruchira Chatterjee and Mohamed Ibrahim and Aaron S Brewster and Iris D Young and Tara Michels-Clark and Andrew Aquila and Mengning Liang …

  99. XFELs open a new era in structural chemical biology

    0.0 out of 5 stars 

    17 Nov 2015 | BioXFEL Publications | Contributor(s): Petra Fromme

    http://dx.doi.org/10.1038/nchembio.1968 Petra Fromme Fromme, P., 2015. XFELs open a new era in structural chemical biology. Nat Chem Biol, 11(12), pp.895–899. Available at: http://dx.doi.org/10.1038/nchembio.1968. NSF-STC Biology with X-ray Lasers (NSF-1231306) journal-article

  100. Polarizability of Six-Helix Bundle and Triangle DNA Origami and Their Escape Characteristics from a Dielectrophoretic Trap

    0.0 out of 5 stars 

    16 Nov 2015 | BioXFEL Publications | Contributor(s): Lin Gan, Fernanda Camacho-Alanis, Alexandra Ros

    http://dx.doi.org/10.1021/acs.analchem.5b02524 Lin Gan and Fernanda Camacho-Alanis and Alexandra Ros Gan, L., Camacho-Alanis, F. & Ros, A., 2015. Polarizability of Six-Helix Bundle and Triangle DNA Origami and Their Escape Characteristics from a Dielectrophoretic Trap. Anal. Chem., 87(24), …