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De novo protein crystal structure determination from X-ray free-electron laser data

08 Jan 2014 | Publications | Contributor(s): J. E. Koglin, T. R. Barends, R. L. Shoeman, L. Foucar, I. Schlichting, S. Boutet, R. B. Doak, K. Nass, G. J. Williams, S. Botha, Mark Messerschmidt

The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …

https://bioxfel.org/resources/238

Protein structural ensembles are revealed by redefining X-ray electron density noise

06 Jan 2014 | Publications | Contributor(s): P. T. Lang, T. Alber, J. S. Fraser, James Holton

To increase the power of X-ray crystallography to determine not only the structures but also the motions of biomolecules, we developed methods to address two classic crystallographic problems: …

https://bioxfel.org/resources/282

Crystallographic data processing for free-electron laser sources

30 Jun 2013 | Publications | Contributor(s): R. A. Kirian, N. A. Zatsepin, F. Stellato, T. A. White, A. Barty, Henry Chapman, James Holton

A processing pipeline for diffraction data acquired using the `serial crystallography' methodology with a free-electron laser source is described with reference to the crystallographic analysis suite …

https://bioxfel.org/resources/236

Simultaneous femtosecond X-ray spectroscopy and diffraction of photosystem II at room temperature

25 Apr 2013 | Publications | Contributor(s): P. D. Adams, C. Glockner, M. J. Latimer, J. E. Koglin, U. Bergmann, R. J. Gildea, J. Sellberg, G. Han, A. R. Fry, P. H. Zwart, S. Gul, J. Hellmich, D. Milathianaki, W. E. White, R. W. Grosse-Kunstleve, N. K. Sauter, B. Lassalle-Kaiser, M. J. Bogan, H. Laksmono, R. G. Sierra, T. C. Weng, J. Messinger, D. W. Schafer, A. Miahnahri, P. Glatzel, S. Boutet, D. Difiore, M. M. Seibert, J. Hattne, V. K. Yach, R. Tran, N. Echols, A. Zouni, J. Yano, G. J. Williams, R. Alonso-Mori, S. Koroidov, J. Kern, D. Sokaras, A. Lampe, Mark Messerschmidt, Ranga Setlur

Intense femtosecond x-ray pulses produced at the Linac Coherent Light Source (LCLS) were used for simultaneous x-ray diffraction (XRD) and x-ray emission spectroscopy (XES) of microcrystals of …

https://bioxfel.org/resources/293

Crystallography: Sources of inspiration

31 Dec 2012 | Publications | Contributor(s): S. McSweeney, Petra Fromme

2014.

https://bioxfel.org/resources/237

Single mimivirus particles intercepted and imaged with an X-ray laser

02 Feb 2011 | Publications | Contributor(s): F. Krasniqi, R. L. Shoeman, J. D. Bozek, H. Gorke, K. U. Kuhnel, C. Caleman, A. Rocker, M. Hantke, D. Rupp, R. G. Sierra, I. Andersson, V. Seltzer, G. Schaller, S. Schorb, J. Ullrich, A. Barty, M. Adolph, D. P. DePonte, B. Rudek, T. Ekeberg, F. Schopper, S. Boutet, J. Krzywinski, H. Hirsemann, L. Gumprecht, C. Reich, B. Erk, N. Kimmel, M. Liang, R. Kirian, J. Andreasson, G. Williams, S. W. Epp, D. Westphal, K. O. Hodgson, C. Bostedt, A. Martin, M. Bott, D. Rolles, R. B. Doak, G. Potdevin, S. Marchesini, J. Schulz, A. Aquila, M. Svenda, L. Struder, D. Odic, B. Nilsson, P. Holl, T. A. White, F. R. Maia, S. Bajt, J. Hajdu, H. Graafsma, L. Foucar, C. D. Schroter, A. Rudenko, N. Coppola, M. J. Bogan, D. Starodub, R. Hartmann, I. Schlichting, G. Weidenspointner, S. Stern, A. Homke, M. Barthelmess, D. Pietschner, C. Abergel, T. Gorkhover, G. Hauser, S. Herrmann, J. M. Claverie, R. Andritschke, H. Soltau, A. A. Miahnahri, M. M. Seibert, L. Lomb, C. Y. Hampton, B. Iwan, O. Jonsson, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …

https://bioxfel.org/resources/294

Reconstruction from a single diffraction pattern of azimuthally projected electron density of molecules aligned parallel to a single axis

31 Dec 2009 | Publications | Contributor(s): V. L. Shneerson, D. Starodub, Dilano Saldin, John Spence

Diffraction from the individual molecules of a molecular beam, aligned parallel to a single axis by a strong electric field or other means, has been proposed as a means of structure determination of …

https://bioxfel.org/resources/286