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De novo protein crystal structure determination from X-ray free-electron laser data

08 Jan 2014 | Publications | Contributor(s): S. Botha, G. J. Williams, T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, S. Boutet, I. Schlichting, R. B. Doak, K. Nass, Mark Messerschmidt

The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …

https://bioxfel.org/resources/238

Protein structural ensembles are revealed by redefining X-ray electron density noise

06 Jan 2014 | Publications | Contributor(s): J. S. Fraser, P. T. Lang, T. Alber, James Holton

To increase the power of X-ray crystallography to determine not only the structures but also the motions of biomolecules, we developed methods to address two classic crystallographic problems: …

https://bioxfel.org/resources/282

Crystallographic data processing for free-electron laser sources

30 Jun 2013 | Publications | Contributor(s): A. Barty, R. A. Kirian, N. A. Zatsepin, F. Stellato, T. A. White, Henry Chapman, James Holton

A processing pipeline for diffraction data acquired using the `serial crystallography' methodology with a free-electron laser source is described with reference to the crystallographic analysis suite …

https://bioxfel.org/resources/236

Simultaneous femtosecond X-ray spectroscopy and diffraction of photosystem II at room temperature

25 Apr 2013 | Publications | Contributor(s): D. Sokaras, T. C. Weng, A. Lampe, R. G. Sierra, J. Kern, S. Boutet, M. J. Latimer, P. Glatzel, J. E. Koglin, C. Glockner, J. Sellberg, N. Echols, G. Han, V. K. Yach, A. R. Fry, R. Tran, D. Milathianaki, S. Koroidov, R. Alonso-Mori, J. Hellmich, M. J. Bogan, P. D. Adams, H. Laksmono, B. Lassalle-Kaiser, D. W. Schafer, U. Bergmann, A. Miahnahri, R. J. Gildea, J. Messinger, D. Difiore, S. Gul, M. M. Seibert, P. H. Zwart, J. Hattne, J. Yano, N. K. Sauter, G. J. Williams, W. E. White, A. Zouni, R. W. Grosse-Kunstleve, Mark Messerschmidt, Ranga Setlur

Intense femtosecond x-ray pulses produced at the Linac Coherent Light Source (LCLS) were used for simultaneous x-ray diffraction (XRD) and x-ray emission spectroscopy (XES) of microcrystals of …

https://bioxfel.org/resources/293

Crystallography: Sources of inspiration

31 Dec 2012 | Publications | Contributor(s): S. McSweeney, Petra Fromme

2014.

https://bioxfel.org/resources/237

Single mimivirus particles intercepted and imaged with an X-ray laser

02 Feb 2011 | Publications | Contributor(s): B. Iwan, I. Schlichting, O. Jonsson, A. A. Miahnahri, G. Weidenspointner, M. M. Seibert, C. Y. Hampton, L. Lomb, R. Hartmann, S. Stern, H. Soltau, D. Rupp, G. Hauser, M. Hantke, C. Caleman, J. M. Claverie, K. U. Kuhnel, A. Rocker, T. Gorkhover, S. Herrmann, R. Andritschke, D. P. DePonte, F. Krasniqi, M. Adolph, B. Rudek, J. D. Bozek, A. Barty, H. Gorke, R. L. Shoeman, B. Erk, I. Andersson, N. Kimmel, G. Schaller, M. Liang, C. Reich, J. Ullrich, L. Gumprecht, V. Seltzer, S. Schorb, R. G. Sierra, D. Rolles, F. Schopper, M. Bott, C. Bostedt, J. Krzywinski, K. O. Hodgson, A. Martin, H. Hirsemann, T. Ekeberg, S. Boutet, L. Struder, B. Nilsson, J. Andreasson, P. Holl, A. Aquila, G. Williams, M. Svenda, D. Odic, D. Westphal, R. Kirian, S. W. Epp, A. Rudenko, N. Coppola, D. Starodub, G. Potdevin, M. J. Bogan, C. D. Schroter, J. Schulz, L. Foucar, S. Marchesini, R. B. Doak, D. Pietschner, F. R. Maia, M. Barthelmess, C. Abergel, J. Hajdu, A. Homke, H. Graafsma, S. Bajt, T. A. White, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …

https://bioxfel.org/resources/294

Reconstruction from a single diffraction pattern of azimuthally projected electron density of molecules aligned parallel to a single axis

31 Dec 2009 | Publications | Contributor(s): D. Starodub, V. L. Shneerson, Dilano Saldin, John Spence

Diffraction from the individual molecules of a molecular beam, aligned parallel to a single axis by a strong electric field or other means, has been proposed as a means of structure determination of …

https://bioxfel.org/resources/286