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De novo protein crystal structure determination from X-ray free-electron laser data

08 Jan 2014 | Publications | Contributor(s): J. E. Koglin, T. R. Barends, R. L. Shoeman, L. Foucar, I. Schlichting, S. Boutet, R. B. Doak, K. Nass, G. J. Williams, S. Botha, Mark Messerschmidt

The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …

https://bioxfel.org/resources/238

Protein structural ensembles are revealed by redefining X-ray electron density noise

06 Jan 2014 | Publications | Contributor(s): P. T. Lang, T. Alber, J. S. Fraser, James Holton

To increase the power of X-ray crystallography to determine not only the structures but also the motions of biomolecules, we developed methods to address two classic crystallographic problems: …

https://bioxfel.org/resources/282

Crystallographic data processing for free-electron laser sources

30 Jun 2013 | Publications | Contributor(s): F. Stellato, T. A. White, A. Barty, R. A. Kirian, N. A. Zatsepin, Henry Chapman, James Holton

A processing pipeline for diffraction data acquired using the `serial crystallography' methodology with a free-electron laser source is described with reference to the crystallographic analysis suite …

https://bioxfel.org/resources/236

Simultaneous femtosecond X-ray spectroscopy and diffraction of photosystem II at room temperature

25 Apr 2013 | Publications | Contributor(s): A. R. Fry, U. Bergmann, J. Sellberg, R. J. Gildea, G. Han, S. Gul, J. Hellmich, P. H. Zwart, D. Milathianaki, H. Laksmono, N. K. Sauter, B. Lassalle-Kaiser, W. E. White, M. J. Bogan, R. W. Grosse-Kunstleve, A. Miahnahri, T. C. Weng, J. Messinger, R. G. Sierra, D. W. Schafer, S. Boutet, J. Hattne, P. Glatzel, D. Difiore, M. M. Seibert, N. Echols, A. Zouni, V. K. Yach, J. Yano, R. Tran, G. J. Williams, A. Lampe, S. Koroidov, J. Kern, R. Alonso-Mori, D. Sokaras, J. E. Koglin, P. D. Adams, C. Glockner, M. J. Latimer, Mark Messerschmidt, Ranga Setlur

Intense femtosecond x-ray pulses produced at the Linac Coherent Light Source (LCLS) were used for simultaneous x-ray diffraction (XRD) and x-ray emission spectroscopy (XES) of microcrystals of …

https://bioxfel.org/resources/293

Crystallography: Sources of inspiration

31 Dec 2012 | Publications | Contributor(s): S. McSweeney, Petra Fromme

2014.

https://bioxfel.org/resources/237

Single mimivirus particles intercepted and imaged with an X-ray laser

02 Feb 2011 | Publications | Contributor(s): D. Westphal, N. Coppola, A. Barty, J. Andreasson, M. J. Bogan, D. P. DePonte, G. Williams, L. Foucar, B. Rudek, S. Stern, R. Hartmann, M. Barthelmess, C. Reich, G. Potdevin, B. Erk, J. Schulz, S. Herrmann, R. Andritschke, T. Gorkhover, C. Bostedt, F. R. Maia, O. Jonsson, A. Martin, J. Hajdu, M. M. Seibert, D. Rolles, H. Graafsma, L. Lomb, R. L. Shoeman, A. Aquila, I. Schlichting, M. Hantke, D. Odic, G. Weidenspointner, K. U. Kuhnel, B. Nilsson, V. Seltzer, S. Schorb, R. G. Sierra, H. Soltau, M. Adolph, C. D. Schroter, G. Hauser, A. Rudenko, J. M. Claverie, D. Starodub, S. Boutet, T. Ekeberg, F. Krasniqi, N. Kimmel, A. Homke, J. D. Bozek, M. Liang, D. Pietschner, H. Gorke, L. Gumprecht, C. Abergel, S. W. Epp, R. Kirian, A. A. Miahnahri, I. Andersson, M. Bott, C. Y. Hampton, G. Schaller, K. O. Hodgson, B. Iwan, J. Ullrich, S. Marchesini, R. B. Doak, L. Struder, C. Caleman, F. Schopper, P. Holl, A. Rocker, J. Krzywinski, M. Svenda, D. Rupp, H. Hirsemann, S. Bajt, T. A. White, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …

https://bioxfel.org/resources/294

Reconstruction from a single diffraction pattern of azimuthally projected electron density of molecules aligned parallel to a single axis

31 Dec 2009 | Publications | Contributor(s): V. L. Shneerson, D. Starodub, Dilano Saldin, John Spence

Diffraction from the individual molecules of a molecular beam, aligned parallel to a single axis by a strong electric field or other means, has been proposed as a means of structure determination of …

https://bioxfel.org/resources/286