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De novo protein crystal structure determination from X-ray free-electron laser data

08 Jan 2014 | Publications | Contributor(s): S. Boutet, I. Schlichting, R. B. Doak, K. Nass, S. Botha, G. J. Williams, J. E. Koglin, T. R. Barends, R. L. Shoeman, L. Foucar, Mark Messerschmidt

The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …

https://bioxfel.org/resources/238

Protein structural ensembles are revealed by redefining X-ray electron density noise

06 Jan 2014 | Publications | Contributor(s): T. Alber, J. S. Fraser, P. T. Lang, James Holton

To increase the power of X-ray crystallography to determine not only the structures but also the motions of biomolecules, we developed methods to address two classic crystallographic problems: …

https://bioxfel.org/resources/282

Crystallographic data processing for free-electron laser sources

30 Jun 2013 | Publications | Contributor(s): A. Barty, R. A. Kirian, N. A. Zatsepin, F. Stellato, T. A. White, Henry Chapman, James Holton

A processing pipeline for diffraction data acquired using the `serial crystallography' methodology with a free-electron laser source is described with reference to the crystallographic analysis suite …

https://bioxfel.org/resources/236

Simultaneous femtosecond X-ray spectroscopy and diffraction of photosystem II at room temperature

25 Apr 2013 | Publications | Contributor(s): R. J. Gildea, G. J. Williams, A. Zouni, U. Bergmann, J. Yano, A. Lampe, S. Gul, J. Kern, P. H. Zwart, D. Sokaras, W. E. White, M. J. Latimer, R. W. Grosse-Kunstleve, J. E. Koglin, N. K. Sauter, C. Glockner, R. G. Sierra, G. Han, A. R. Fry, T. C. Weng, J. Sellberg, S. Boutet, J. Hellmich, P. Glatzel, D. Milathianaki, R. Tran, H. Laksmono, N. Echols, B. Lassalle-Kaiser, V. K. Yach, M. J. Bogan, D. W. Schafer, A. Miahnahri, S. Koroidov, J. Messinger, R. Alonso-Mori, M. M. Seibert, J. Hattne, P. D. Adams, D. Difiore, Mark Messerschmidt, Ranga Setlur

Intense femtosecond x-ray pulses produced at the Linac Coherent Light Source (LCLS) were used for simultaneous x-ray diffraction (XRD) and x-ray emission spectroscopy (XES) of microcrystals of …

https://bioxfel.org/resources/293

Crystallography: Sources of inspiration

31 Dec 2012 | Publications | Contributor(s): S. McSweeney, Petra Fromme

2014.

https://bioxfel.org/resources/237

Single mimivirus particles intercepted and imaged with an X-ray laser

02 Feb 2011 | Publications | Contributor(s): M. Svenda, L. Struder, S. Marchesini, P. Holl, R. B. Doak, A. Aquila, F. Schopper, D. Odic, J. Krzywinski, B. Nilsson, H. Hirsemann, T. A. White, L. Foucar, S. Bajt, N. Coppola, M. J. Bogan, C. D. Schroter, J. Andreasson, A. Rudenko, G. Williams, D. Starodub, D. Westphal, R. Hartmann, M. Barthelmess, S. Stern, A. Homke, G. Potdevin, D. Pietschner, J. Schulz, C. Abergel, T. Gorkhover, L. Lomb, S. Herrmann, O. Jonsson, R. Andritschke, M. M. Seibert, A. A. Miahnahri, F. R. Maia, C. Y. Hampton, J. Hajdu, B. Iwan, H. Graafsma, K. U. Kuhnel, R. L. Shoeman, M. Hantke, C. Caleman, I. Schlichting, A. Rocker, G. Weidenspointner, D. Rupp, R. G. Sierra, V. Seltzer, M. Adolph, S. Schorb, A. Barty, G. Hauser, D. P. DePonte, J. M. Claverie, B. Rudek, H. Soltau, T. Ekeberg, L. Gumprecht, S. Boutet, N. Kimmel, M. Liang, C. Reich, J. D. Bozek, B. Erk, H. Gorke, F. Krasniqi, R. Kirian, M. Bott, S. W. Epp, K. O. Hodgson, C. Bostedt, I. Andersson, A. Martin, G. Schaller, D. Rolles, J. Ullrich, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …

https://bioxfel.org/resources/294

Reconstruction from a single diffraction pattern of azimuthally projected electron density of molecules aligned parallel to a single axis

31 Dec 2009 | Publications | Contributor(s): V. L. Shneerson, D. Starodub, Dilano Saldin, John Spence

Diffraction from the individual molecules of a molecular beam, aligned parallel to a single axis by a strong electric field or other means, has been proposed as a means of structure determination of …

https://bioxfel.org/resources/286