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De novo protein crystal structure determination from X-ray free-electron laser data

08 Jan 2014 | Publications | Contributor(s): S. Boutet, I. Schlichting, R. B. Doak, K. Nass, S. Botha, G. J. Williams, T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, Mark Messerschmidt

The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …

https://bioxfel.org/resources/238

Protein structural ensembles are revealed by redefining X-ray electron density noise

06 Jan 2014 | Publications | Contributor(s): T. Alber, J. S. Fraser, P. T. Lang, James Holton

To increase the power of X-ray crystallography to determine not only the structures but also the motions of biomolecules, we developed methods to address two classic crystallographic problems: …

https://bioxfel.org/resources/282

Crystallographic data processing for free-electron laser sources

30 Jun 2013 | Publications | Contributor(s): A. Barty, R. A. Kirian, N. A. Zatsepin, F. Stellato, T. A. White, Henry Chapman, James Holton

A processing pipeline for diffraction data acquired using the `serial crystallography' methodology with a free-electron laser source is described with reference to the crystallographic analysis suite …

https://bioxfel.org/resources/236

Simultaneous femtosecond X-ray spectroscopy and diffraction of photosystem II at room temperature

25 Apr 2013 | Publications | Contributor(s): J. Yano, S. Boutet, G. J. Williams, P. Glatzel, A. Zouni, J. Kern, R. Tran, D. Sokaras, N. Echols, A. Lampe, V. K. Yach, R. Alonso-Mori, C. Glockner, M. J. Latimer, S. Koroidov, J. E. Koglin, J. Sellberg, G. Han, P. D. Adams, A. R. Fry, R. J. Gildea, D. Milathianaki, U. Bergmann, J. Hellmich, B. Lassalle-Kaiser, M. J. Bogan, S. Gul, H. Laksmono, P. H. Zwart, W. E. White, J. Messinger, R. W. Grosse-Kunstleve, D. W. Schafer, N. K. Sauter, A. Miahnahri, R. G. Sierra, D. Difiore, M. M. Seibert, T. C. Weng, J. Hattne, Mark Messerschmidt, Ranga Setlur

Intense femtosecond x-ray pulses produced at the Linac Coherent Light Source (LCLS) were used for simultaneous x-ray diffraction (XRD) and x-ray emission spectroscopy (XES) of microcrystals of …

https://bioxfel.org/resources/293

Crystallography: Sources of inspiration

31 Dec 2012 | Publications | Contributor(s): S. McSweeney, Petra Fromme

2014.

https://bioxfel.org/resources/237

Single mimivirus particles intercepted and imaged with an X-ray laser

02 Feb 2011 | Publications | Contributor(s): T. Ekeberg, S. Boutet, M. Svenda, J. M. Claverie, D. Pietschner, L. Struder, H. Soltau, C. Abergel, P. Holl, G. Hauser, A. Homke, S. W. Epp, R. Kirian, C. Y. Hampton, L. Foucar, H. Gorke, B. Iwan, N. Coppola, F. Krasniqi, A. A. Miahnahri, M. J. Bogan, J. D. Bozek, S. Marchesini, R. B. Doak, G. Schaller, A. Rocker, J. Ullrich, D. Rupp, M. Barthelmess, I. Andersson, C. Caleman, T. A. White, S. Bajt, J. Krzywinski, D. P. DePonte, L. Lomb, H. Hirsemann, B. Rudek, O. Jonsson, F. Schopper, A. Barty, M. M. Seibert, S. Stern, R. Hartmann, K. U. Kuhnel, G. Williams, B. Erk, D. Westphal, M. Hantke, J. Andreasson, C. Reich, R. Andritschke, T. Gorkhover, S. Herrmann, A. Martin, J. Schulz, D. Rolles, M. Adolph, C. Bostedt, G. Potdevin, R. L. Shoeman, J. Hajdu, D. Odic, L. Gumprecht, H. Graafsma, B. Nilsson, N. Kimmel, F. R. Maia, A. Aquila, M. Liang, S. Schorb, R. G. Sierra, V. Seltzer, G. Weidenspointner, A. Rudenko, D. Starodub, M. Bott, I. Schlichting, C. D. Schroter, K. O. Hodgson, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …

https://bioxfel.org/resources/294

Reconstruction from a single diffraction pattern of azimuthally projected electron density of molecules aligned parallel to a single axis

31 Dec 2009 | Publications | Contributor(s): V. L. Shneerson, D. Starodub, Dilano Saldin, John Spence

Diffraction from the individual molecules of a molecular beam, aligned parallel to a single axis by a strong electric field or other means, has been proposed as a means of structure determination of …

https://bioxfel.org/resources/286