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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, S. Boutet, I. Schlichting, R. B. Doak, K. Nass, G. J. Williams, S. Botha, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://bioxfel.org/resources/De-novo-protein-crystal-structure
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Protein structural ensembles are revealed by redefining X-ray electron density noise
06 Jan 2014 | Publications | Contributor(s): T. Alber, J. S. Fraser, P. T. Lang, James Holton
To increase the power of X-ray crystallography to determine not only the structures but also the motions of biomolecules, we developed methods to address two classic crystallographic problems: …
https://bioxfel.org/resources/Protein-structural-ensembles-are-revealed
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Crystallographic data processing for free-electron laser sources
30 Jun 2013 | Publications | Contributor(s): A. Barty, R. A. Kirian, N. A. Zatsepin, F. Stellato, T. A. White, Henry Chapman, James Holton
A processing pipeline for diffraction data acquired using the `serial crystallography' methodology with a free-electron laser source is described with reference to the crystallographic analysis suite …
https://bioxfel.org/resources/Crystallographic-data-processing-for-free-electron
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Simultaneous femtosecond X-ray spectroscopy and diffraction of photosystem II at room temperature
25 Apr 2013 | Publications | Contributor(s): D. Difiore, M. M. Seibert, J. Hattne, P. D. Adams, A. Zouni, J. Yano, G. J. Williams, U. Bergmann, R. J. Gildea, J. Kern, D. Sokaras, A. Lampe, S. Gul, P. H. Zwart, C. Glockner, M. J. Latimer, J. E. Koglin, R. W. Grosse-Kunstleve, N. K. Sauter, W. E. White, J. Sellberg, G. Han, A. R. Fry, T. C. Weng, R. G. Sierra, J. Hellmich, D. Milathianaki, S. Boutet, P. Glatzel, B. Lassalle-Kaiser, M. J. Bogan, H. Laksmono, N. Echols, V. K. Yach, R. Tran, J. Messinger, D. W. Schafer, A. Miahnahri, S. Koroidov, R. Alonso-Mori, Mark Messerschmidt, Ranga Setlur
Intense femtosecond x-ray pulses produced at the Linac Coherent Light Source (LCLS) were used for simultaneous x-ray diffraction (XRD) and x-ray emission spectroscopy (XES) of microcrystals of …
https://bioxfel.org/resources/Simultaneous-femtosecond-X-ray-spectroscopy-and
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Crystallography: Sources of inspiration
31 Dec 2012 | Publications | Contributor(s): S. McSweeney, Petra Fromme
2014.
https://bioxfel.org/resources/Crystallography:-Sources-of-inspiration
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): K. U. Kuhnel, A. Rudenko, D. Starodub, M. Hantke, C. D. Schroter, S. W. Epp, H. Hirsemann, R. Kirian, F. Schopper, J. Krzywinski, A. Homke, D. Pietschner, M. Adolph, C. Abergel, R. B. Doak, D. Westphal, J. Andreasson, S. Marchesini, G. Williams, C. Y. Hampton, L. Gumprecht, B. Iwan, N. Kimmel, A. A. Miahnahri, M. Liang, T. A. White, S. Bajt, G. Potdevin, J. Schulz, A. Rocker, D. Rupp, M. Bott, C. Caleman, K. O. Hodgson, H. Graafsma, R. Hartmann, F. R. Maia, J. Hajdu, S. Stern, M. Svenda, D. P. DePonte, L. Struder, B. Rudek, P. Holl, A. Barty, R. Andritschke, T. Gorkhover, I. Schlichting, S. Herrmann, G. Weidenspointner, C. Reich, L. Foucar, B. Erk, N. Coppola, M. J. Bogan, H. Soltau, R. L. Shoeman, G. Hauser, J. M. Claverie, A. Martin, D. Rolles, M. Barthelmess, C. Bostedt, R. G. Sierra, F. Krasniqi, V. Seltzer, J. D. Bozek, S. Schorb, H. Gorke, D. Odic, L. Lomb, B. Nilsson, O. Jonsson, A. Aquila, M. M. Seibert, J. Ullrich, T. Ekeberg, I. Andersson, S. Boutet, G. Schaller, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://bioxfel.org/resources/Single-mimivirus-particles-intercepted-and
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Reconstruction from a single diffraction pattern of azimuthally projected electron density of molecules aligned parallel to a single axis
31 Dec 2009 | Publications | Contributor(s): V. L. Shneerson, D. Starodub, Dilano Saldin, John Spence
Diffraction from the individual molecules of a molecular beam, aligned parallel to a single axis by a strong electric field or other means, has been proposed as a means of structure determination of …
https://bioxfel.org/resources/Reconstruction-from-a-single-diffraction
