Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): L. Str¸der, A. Hartmann, T. A. White, R. Hartmann, F. Krasniqi, C. Reich, I. Schlichting, G. Weidenspointner, S. Stern, D. Rolles, B. Rudek, S. Kassemeyer, L. Johansson, J. Schulz, H. Soltau, C. Y. Hampton, M. J. Bogan, A. Rudenko, R. Neutze, F. Stellato, N. Kimmel, J. D. Bozek, H. Fleckenstein, K.-U. K¸hnel, A. Barty, R. B. Doak, E. Malmerberg, C. Caleman, I. Grotjohann, P. Holl, D. P. DePonte, M. M. Seibert, B. Erk, X. Wang, S. a. Bajt, G. n. Hauser, L. Gumprecht, J. Hajdu, H. Hirsemann, M. Barthelmess, A. Hˆmke, T. R. M. Barends, R. L. Shoeman, F. R. N. C. Maia, N. Coppola, C. Wunderer, J. Andreasson, H. Bottin, K. Nass, A. Aquila, S. W. Epp, R. A. Kirian, D. Starodub, C. Bostedt, S. Marchesini, L. Lomb, J. Ullrich, D. Arnlund, M. Liang, A. V. Martin, V. Elser, R. Sierra, G. J. Williams, N. Timneanu, L. Foucar, J. Davidsson, H. Graafsma, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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