Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): S. W. Epp, C. Y. Hampton, A. Rudenko, S. Marchesini, F. Stellato, R. A. Kirian, L. Lomb, J. Ullrich, C. Caleman, M. Liang, A. Barty, R. Sierra, V. Elser, E. Malmerberg, N. Timneanu, J. Davidsson, H. Graafsma, L. Foucar, G. n. Hauser, R. Hartmann, T. A. White, D. P. DePonte, B. Erk, L. Str¸der, G. Weidenspointner, I. Schlichting, S. Stern, C. Wunderer, A. Hˆmke, S. Kassemeyer, F. R. N. C. Maia, L. Johansson, J. Schulz, H. Soltau, A. Aquila, R. Neutze, D. Starodub, N. Kimmel, C. Bostedt, M. J. Bogan, J. D. Bozek, H. Fleckenstein, K.-U. K¸hnel, G. J. Williams, R. B. Doak, D. Arnlund, A. V. Martin, I. Grotjohann, C. Reich, M. M. Seibert, A. Hartmann, S. a. Bajt, X. Wang, F. Krasniqi, P. Holl, J. Hajdu, H. Hirsemann, L. Gumprecht, R. L. Shoeman, T. R. M. Barends, D. Rolles, N. Coppola, B. Rudek, M. Barthelmess, J. Andreasson, H. Bottin, K. Nass, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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