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Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals

28 Feb 2011 | Publications | Contributor(s): L. Lomb, T. A. White, A. Barty, R. A. Kirian, F. R. Maia, A. Aquila, X. Wang, A. V. Martin, Henry Chapman, Petra Fromme, James Holton, Mark S. Hunter, Marius Schmidt, John Spence

A complete set of structure factors has been extracted from hundreds of thousands of femtosecond single-shot X-ray microdiffraction patterns taken from randomly oriented nanocrystals. The method of …

https://bioxfel.org/resources/Structure-factor-analysis-of-femtosecond-microdiffraction

Femtosecond X-ray protein nanocrystallography

02 Feb 2011 | Publications | Contributor(s): D. Pietschner, N. Kimmel, B. Nilsson, M. Liang, S. Boutet, G. J. Williams, J. Schulz, T. Gorkhover, R. A. Kirian, C. Reich, A. Rudenko, M. Barthelmess, F. R. Maia, K. U. Kuhnel, J. D. Bozek, S. W. Epp, H. Graafsma, R. L. Shoeman, M. Svenda, A. Barty, L. Lomb, D. Rupp, O. Jonsson, C. Bostedt, I. Grotjohann, S. Marchesini, G. Schaller, R. B. Doak, D. P. DePonte, N. Coppola, B. Erk, M. J. Bogan, G. Hauser, S. Bajt, J. Krzywinski, T. A. White, H. Soltau, C. D. Schroter, A. Rocker, M. Adolph, F. Krasniqi, J. Andreasson, S. Stern, H. Gorke, R. Hartmann, K. Nass, M. M. Seibert, A. Aquila, L. Gumprecht, D. Rolles, N. Timneanu, B. Rudek, I. Andersson, S. Herrmann, G. Potdevin, J. Ullrich, T. R. Barends, R. Andritschke, C. Y. Hampton, A. V. Martin, M. Bott, F. Schopper, L. Foucar, J. Hajdu, H. Hirsemann, R. Neutze, A. Homke, L. Struder, D. Starodub, P. Holl, C. Caleman, X. Wang, I. Schlichting, S. Schorb, G. Weidenspointner, R. G. Sierra, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …

https://bioxfel.org/resources/Femtosecond-X-ray-protein-nanocrystallography

X-ray diffraction from membrane protein nanocrystals

04 Jan 2011 | Publications | Contributor(s): R. B. Doak, D. P. DePonte, R. A. Kirian, D. A. Shapiro, S. Marchesini, D. Starodub, X. Wang, Petra Fromme, Mark S. Hunter, John Spence, Uwe Weierstall

Membrane proteins constitute > 30% of the proteins in an average cell, and yet the number of currently known structures of unique membrane proteins is < 300. To develop new concepts for membrane …

https://bioxfel.org/resources/X-ray-diffraction-from-membrane-protein