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Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals

28 Feb 2011 | Publications | Contributor(s): F. R. Maia, R. A. Kirian, A. Aquila, X. Wang, A. V. Martin, L. Lomb, T. A. White, A. Barty, Henry Chapman, Petra Fromme, James Holton, Mark S. Hunter, Marius Schmidt, John Spence

A complete set of structure factors has been extracted from hundreds of thousands of femtosecond single-shot X-ray microdiffraction patterns taken from randomly oriented nanocrystals. The method of …

https://bioxfel.org/resources/Structure-factor-analysis-of-femtosecond-microdiffraction

Femtosecond X-ray protein nanocrystallography

02 Feb 2011 | Publications | Contributor(s): A. Barty, J. Krzywinski, D. Rupp, H. Soltau, C. Bostedt, S. Stern, R. Andritschke, R. Hartmann, M. Bott, K. Nass, G. Hauser, J. Andreasson, D. P. DePonte, H. Gorke, B. Erk, T. R. Barends, L. Struder, S. Herrmann, P. Holl, I. Andersson, C. D. Schroter, G. Potdevin, A. Rocker, J. Ullrich, F. Krasniqi, M. Liang, R. Neutze, N. Kimmel, L. Foucar, A. Aquila, J. Hajdu, D. Rolles, H. Hirsemann, B. Rudek, S. Schorb, R. A. Kirian, R. G. Sierra, X. Wang, M. Barthelmess, I. Schlichting, C. Y. Hampton, G. Weidenspointner, A. V. Martin, F. Schopper, M. Svenda, T. Gorkhover, L. Lomb, S. Boutet, O. Jonsson, C. Caleman, G. J. Williams, A. Homke, J. Schulz, D. Starodub, S. W. Epp, R. B. Doak, R. L. Shoeman, N. Coppola, M. J. Bogan, K. U. Kuhnel, J. D. Bozek, D. Pietschner, H. Graafsma, B. Nilsson, M. Adolph, S. Marchesini, I. Grotjohann, C. Reich, G. Schaller, A. Rudenko, F. R. Maia, M. M. Seibert, T. A. White, L. Gumprecht, S. Bajt, N. Timneanu, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …

https://bioxfel.org/resources/Femtosecond-X-ray-protein-nanocrystallography

X-ray diffraction from membrane protein nanocrystals

04 Jan 2011 | Publications | Contributor(s): D. P. DePonte, R. A. Kirian, S. Marchesini, D. A. Shapiro, X. Wang, D. Starodub, R. B. Doak, Petra Fromme, Mark S. Hunter, John Spence, Uwe Weierstall

Membrane proteins constitute > 30% of the proteins in an average cell, and yet the number of currently known structures of unique membrane proteins is < 300. To develop new concepts for membrane …

https://bioxfel.org/resources/X-ray-diffraction-from-membrane-protein