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Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals

28 Feb 2011 | Publications | Contributor(s): A. V. Martin, L. Lomb, T. A. White, A. Barty, R. A. Kirian, F. R. Maia, A. Aquila, X. Wang, Henry Chapman, Petra Fromme, James Holton, Mark S. Hunter, Marius Schmidt, John Spence

A complete set of structure factors has been extracted from hundreds of thousands of femtosecond single-shot X-ray microdiffraction patterns taken from randomly oriented nanocrystals. The method of …

https://bioxfel.org/resources/Structure-factor-analysis-of-femtosecond-microdiffraction

Femtosecond X-ray protein nanocrystallography

02 Feb 2011 | Publications | Contributor(s): J. Schulz, L. Gumprecht, N. Timneanu, G. J. Williams, M. M. Seibert, R. Hartmann, A. Homke, D. Starodub, S. Stern, C. Caleman, H. Graafsma, K. U. Kuhnel, M. Bott, J. D. Bozek, R. Andritschke, T. R. Barends, D. Pietschner, S. Herrmann, B. Nilsson, G. Schaller, L. Struder, I. Grotjohann, P. Holl, C. Reich, R. Neutze, A. Rudenko, F. R. Maia, J. Krzywinski, H. Soltau, N. Kimmel, M. Liang, R. G. Sierra, A. Barty, X. Wang, D. Rupp, S. Schorb, C. Bostedt, H. Gorke, K. Nass, M. Barthelmess, J. Andreasson, R. A. Kirian, G. Hauser, T. Gorkhover, D. P. DePonte, S. Boutet, B. Erk, J. Ullrich, L. Lomb, I. Andersson, O. Jonsson, G. Potdevin, M. Svenda, S. W. Epp, C. D. Schroter, R. L. Shoeman, A. Rocker, F. Krasniqi, J. Hajdu, R. B. Doak, H. Hirsemann, N. Coppola, L. Foucar, M. J. Bogan, A. Aquila, D. Rolles, S. Marchesini, B. Rudek, G. Weidenspointner, M. Adolph, I. Schlichting, T. A. White, C. Y. Hampton, S. Bajt, A. V. Martin, F. Schopper, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …

https://bioxfel.org/resources/Femtosecond-X-ray-protein-nanocrystallography

X-ray diffraction from membrane protein nanocrystals

04 Jan 2011 | Publications | Contributor(s): D. Starodub, X. Wang, R. B. Doak, D. P. DePonte, R. A. Kirian, D. A. Shapiro, S. Marchesini, Petra Fromme, Mark S. Hunter, John Spence, Uwe Weierstall

Membrane proteins constitute > 30% of the proteins in an average cell, and yet the number of currently known structures of unique membrane proteins is < 300. To develop new concepts for membrane …

https://bioxfel.org/resources/X-ray-diffraction-from-membrane-protein