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Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals

28 Feb 2011 | Publications | Contributor(s): R. A. Kirian, F. R. Maia, A. Aquila, X. Wang, A. V. Martin, L. Lomb, T. A. White, A. Barty, Henry Chapman, Petra Fromme, James Holton, Mark S. Hunter, Marius Schmidt, John Spence

A complete set of structure factors has been extracted from hundreds of thousands of femtosecond single-shot X-ray microdiffraction patterns taken from randomly oriented nanocrystals. The method of …

https://bioxfel.org/resources/Structure-factor-analysis-of-femtosecond-microdiffraction

Femtosecond X-ray protein nanocrystallography

02 Feb 2011 | Publications | Contributor(s): O. Jonsson, F. Krasniqi, M. Svenda, C. D. Schroter, L. Lomb, A. Rocker, H. Graafsma, R. G. Sierra, K. U. Kuhnel, X. Wang, J. D. Bozek, S. Schorb, D. Rolles, M. J. Bogan, B. Rudek, R. B. Doak, A. Aquila, N. Coppola, T. Gorkhover, I. Grotjohann, S. Boutet, G. Schaller, A. V. Martin, F. Schopper, C. Y. Hampton, M. Adolph, S. W. Epp, H. Soltau, R. L. Shoeman, J. Krzywinski, D. Starodub, M. M. Seibert, C. Caleman, L. Gumprecht, A. Homke, N. Timneanu, K. Nass, J. Andreasson, S. Marchesini, H. Gorke, B. Nilsson, R. Andritschke, D. Pietschner, M. Bott, J. Ullrich, T. A. White, I. Andersson, S. Bajt, G. Potdevin, P. Holl, F. R. Maia, C. Reich, L. Struder, A. Rudenko, S. Stern, H. Hirsemann, R. Hartmann, L. Foucar, J. Hajdu, D. Rupp, M. Liang, C. Bostedt, A. Barty, N. Kimmel, T. R. Barends, I. Schlichting, S. Herrmann, G. Weidenspointner, B. Erk, R. A. Kirian, G. Hauser, D. P. DePonte, M. Barthelmess, R. Neutze, G. J. Williams, J. Schulz, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …

https://bioxfel.org/resources/Femtosecond-X-ray-protein-nanocrystallography

X-ray diffraction from membrane protein nanocrystals

04 Jan 2011 | Publications | Contributor(s): S. Marchesini, D. A. Shapiro, X. Wang, D. Starodub, R. B. Doak, D. P. DePonte, R. A. Kirian, Petra Fromme, Mark S. Hunter, John Spence, Uwe Weierstall

Membrane proteins constitute > 30% of the proteins in an average cell, and yet the number of currently known structures of unique membrane proteins is < 300. To develop new concepts for membrane …

https://bioxfel.org/resources/X-ray-diffraction-from-membrane-protein