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Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals

28 Feb 2011 | Publications | Contributor(s): R. A. Kirian, F. R. Maia, A. Aquila, X. Wang, A. V. Martin, L. Lomb, T. A. White, A. Barty, Henry Chapman, Petra Fromme, James Holton, Mark S. Hunter, Marius Schmidt, John Spence

A complete set of structure factors has been extracted from hundreds of thousands of femtosecond single-shot X-ray microdiffraction patterns taken from randomly oriented nanocrystals. The method of …

https://bioxfel.org/resources/Structure-factor-analysis-of-femtosecond-microdiffraction

Femtosecond X-ray protein nanocrystallography

02 Feb 2011 | Publications | Contributor(s): G. Schaller, S. Bajt, D. P. DePonte, N. Timneanu, B. Erk, M. M. Seibert, I. Grotjohann, T. A. White, G. Hauser, L. Gumprecht, J. Krzywinski, A. Rocker, M. Bott, H. Soltau, S. Stern, F. Krasniqi, R. Andritschke, R. Hartmann, C. D. Schroter, L. Struder, H. Gorke, S. Herrmann, D. Rolles, P. Holl, K. Nass, B. Rudek, J. Andreasson, A. Aquila, T. R. Barends, G. Potdevin, R. Neutze, C. Y. Hampton, N. Kimmel, J. Ullrich, A. V. Martin, M. Liang, I. Andersson, F. Schopper, J. Hajdu, A. Homke, X. Wang, M. Barthelmess, H. Hirsemann, S. Schorb, D. Starodub, R. A. Kirian, L. Foucar, R. G. Sierra, C. Caleman, G. Weidenspointner, S. Boutet, D. Pietschner, O. Jonsson, B. Nilsson, M. Svenda, I. Schlichting, T. Gorkhover, L. Lomb, N. Coppola, J. Schulz, A. Rudenko, M. J. Bogan, S. W. Epp, F. R. Maia, R. B. Doak, G. J. Williams, R. L. Shoeman, C. Reich, J. D. Bozek, A. Barty, M. Adolph, H. Graafsma, S. Marchesini, D. Rupp, K. U. Kuhnel, C. Bostedt, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …

https://bioxfel.org/resources/Femtosecond-X-ray-protein-nanocrystallography

X-ray diffraction from membrane protein nanocrystals

04 Jan 2011 | Publications | Contributor(s): D. P. DePonte, R. A. Kirian, D. A. Shapiro, S. Marchesini, X. Wang, D. Starodub, R. B. Doak, Petra Fromme, Mark S. Hunter, John Spence, Uwe Weierstall

Membrane proteins constitute > 30% of the proteins in an average cell, and yet the number of currently known structures of unique membrane proteins is < 300. To develop new concepts for membrane …

https://bioxfel.org/resources/X-ray-diffraction-from-membrane-protein