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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, S. Boutet, I. Schlichting, R. B. Doak, K. Nass, G. J. Williams, S. Botha, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://bioxfel.org/resources/238
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): I. Grotjohann, G. Schaller, R. Neutze, G. Hauser, D. P. DePonte, N. Kimmel, B. Erk, M. Liang, R. G. Sierra, J. Krzywinski, X. Wang, H. Soltau, S. Schorb, R. A. Kirian, C. D. Schroter, A. Rocker, M. Barthelmess, F. Krasniqi, J. Andreasson, T. Gorkhover, H. Gorke, S. Boutet, K. Nass, M. Svenda, A. Aquila, L. Lomb, D. Rolles, O. Jonsson, B. Rudek, S. W. Epp, G. Potdevin, R. L. Shoeman, J. Ullrich, I. Andersson, R. B. Doak, C. Y. Hampton, N. Coppola, A. V. Martin, M. J. Bogan, F. Schopper, L. Foucar, J. Hajdu, H. Hirsemann, S. Marchesini, C. Caleman, A. Homke, M. Adolph, D. Starodub, I. Schlichting, T. A. White, G. Weidenspointner, S. Bajt, L. Gumprecht, D. Pietschner, N. Timneanu, B. Nilsson, M. M. Seibert, S. Stern, G. J. Williams, R. Hartmann, J. Schulz, R. Andritschke, C. Reich, A. Rudenko, M. Bott, F. R. Maia, J. D. Bozek, T. R. Barends, H. Graafsma, S. Herrmann, K. U. Kuhnel, A. Barty, L. Struder, D. Rupp, P. Holl, C. Bostedt, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://bioxfel.org/resources/252
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): S. Boutet, R. A. Kirian, D. Wang, I. Grotjohann, C. Wang, T. A. White, A. Barty, K. R. Beyerlein, G. W. Han, S. Basu, D. Wacker, V. Katritch, C. Gati, M. M. Seibert, S. T. Shah, K. N. Rendek, G. J. Williams, R. C. Stevens, W. Liu, J. E. Koglin, N. A. Zatsepin, M. Caffrey, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://bioxfel.org/resources/290
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): H. Graafsma, S. Schorb, F. R. Maia, R. G. Sierra, J. Hajdu, V. Seltzer, D. Starodub, C. D. Schroter, A. Rudenko, M. Adolph, I. Schlichting, T. Ekeberg, G. Weidenspointner, S. Boutet, N. Kimmel, C. Abergel, M. Liang, A. Homke, L. Gumprecht, D. Pietschner, H. Soltau, S. W. Epp, G. Hauser, R. Kirian, J. M. Claverie, M. Bott, A. A. Miahnahri, K. O. Hodgson, C. Y. Hampton, B. Iwan, S. Marchesini, F. Krasniqi, R. B. Doak, J. D. Bozek, H. Gorke, P. Holl, C. Caleman, M. Svenda, A. Rocker, L. Struder, D. Rupp, J. Ullrich, I. Andersson, T. A. White, G. Schaller, S. Bajt, B. Rudek, M. J. Bogan, A. Barty, L. Foucar, D. P. DePonte, N. Coppola, H. Hirsemann, S. Stern, F. Schopper, R. Hartmann, J. Krzywinski, C. Reich, B. Erk, M. Barthelmess, S. Herrmann, D. Westphal, R. Andritschke, J. Andreasson, T. Gorkhover, G. Williams, O. Jonsson, C. Bostedt, M. M. Seibert, A. Martin, L. Lomb, D. Rolles, G. Potdevin, R. L. Shoeman, J. Schulz, M. Hantke, A. Aquila, K. U. Kuhnel, D. Odic, B. Nilsson, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://bioxfel.org/resources/294