Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): S. Marchesini, R. A. Kirian, J. Andreasson, D. Starodub, H. Bottin, C. Bostedt, X. Wang, K. Nass, A. Aquila, N. Timneanu, M. Liang, R. Sierra, L. Lomb, A. V. Martin, T. R. M. Barends, J. Ullrich, G. J. Williams, D. Arnlund, L. Str¸der, R. Hartmann, S. W. Epp, J. Davidsson, F. Krasniqi, H. Graafsma, C. Reich, L. Foucar, A. Hartmann, S. Kassemeyer, D. Rolles, G. Weidenspointner, B. Rudek, V. Elser, I. Schlichting, N. Kimmel, M. J. Bogan, R. Neutze, L. Johansson, A. Rudenko, T. A. White, J. Schulz, F. Stellato, H. Soltau, C. Y. Hampton, R. B. Doak, S. Stern, J. D. Bozek, E. Malmerberg, H. Fleckenstein, C. Caleman, K.-U. K¸hnel, A. Barty, P. Holl, M. M. Seibert, S. a. Bajt, B. Erk, G. n. Hauser, I. Grotjohann, D. P. DePonte, M. Barthelmess, R. L. Shoeman, N. Coppola, L. Gumprecht, A. Hˆmke, J. Hajdu, F. R. N. C. Maia, H. Hirsemann, C. Wunderer, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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