Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): H. Hirsemann, L. Gumprecht, S. W. Epp, J. Hajdu, A. Barty, E. Malmerberg, S. Kassemeyer, C. Caleman, V. Elser, K. Nass, J. Andreasson, H. Bottin, D. P. DePonte, R. Neutze, B. Erk, N. Kimmel, M. J. Bogan, G. n. Hauser, J. Ullrich, L. Lomb, T. A. White, A. Hˆmke, F. R. N. C. Maia, C. Wunderer, R. B. Doak, H. Graafsma, L. Foucar, S. Stern, J. Davidsson, D. Starodub, S. a. Bajt, C. Bostedt, P. Holl, A. Aquila, M. M. Seibert, I. Schlichting, G. Weidenspointner, D. Arnlund, R. L. Shoeman, A. V. Martin, N. Coppola, M. Barthelmess, G. J. Williams, J. Schulz, H. Soltau, L. Johansson, A. Hartmann, F. Krasniqi, S. Marchesini, C. Reich, R. A. Kirian, H. Fleckenstein, X. Wang, K.-U. K¸hnel, J. D. Bozek, D. Rolles, R. Sierra, B. Rudek, N. Timneanu, M. Liang, I. Grotjohann, T. R. M. Barends, C. Y. Hampton, R. Hartmann, A. Rudenko, L. Str¸der, F. Stellato, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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