Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): S. Kassemeyer, B. Erk, J. Andreasson, G. n. Hauser, H. Bottin, X. Wang, D. P. DePonte, K. Nass, N. Kimmel, M. J. Bogan, R. Neutze, F. R. N. C. Maia, L. Lomb, T. R. M. Barends, C. Wunderer, J. Ullrich, A. Hˆmke, R. B. Doak, S. W. Epp, C. Bostedt, J. Davidsson, A. Aquila, H. Graafsma, D. Starodub, L. Foucar, P. Holl, M. M. Seibert, S. a. Bajt, G. J. Williams, G. Weidenspointner, V. Elser, D. Arnlund, A. V. Martin, I. Schlichting, N. Coppola, M. Barthelmess, R. L. Shoeman, F. Krasniqi, L. Johansson, T. A. White, C. Reich, J. Schulz, A. Hartmann, H. Soltau, S. Marchesini, R. A. Kirian, S. Stern, B. Rudek, J. D. Bozek, H. Fleckenstein, D. Rolles, K.-U. K¸hnel, N. Timneanu, M. Liang, R. Sierra, F. Stellato, C. Y. Hampton, A. Rudenko, I. Grotjohann, L. Str¸der, R. Hartmann, L. Gumprecht, C. Caleman, J. Hajdu, A. Barty, H. Hirsemann, E. Malmerberg, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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