What's New: Fiscal Year 2016

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  1. Extracting water and ion distributions from solution x-ray scattering experiments

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    03 Jun 2016 | BioXFEL Publications | Contributor(s): Hung T. Nguyen, Suzette A. Pabit, Lois Pollack, David Case

    http://dx.doi.org/10.1063/1.4953037 journal-article Nguyen, H.T. et al., 2016. Extracting water and ion distributions from solution x-ray scattering experiments. The Journal of Chemical Physics, …

    https://bioxfel.org/resources/1383

  2. Toward Analysis of Proteins in Single Cells: A Quantitative Approach Employing Isobaric Tags with MALDI Mass Spectrometry Realized with a Microfluidic Platform

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    03 Jun 2016 | BioXFEL Publications | Contributor(s): Mian Yang, Randall Nelson, Alexandra Ros

    http://dx.doi.org/10.1021/acs.analchem.5b03419 journal-article Yang, M., Nelson, R. & Ros, A., 2016. Toward Analysis of Proteins in Single Cells: A Quantitative Approach Employing Isobaric Tags …

    https://bioxfel.org/resources/1405

  3. The Dependence of Carbohydrate–Aromatic Interaction Strengths on the Structure of the Carbohydrate

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    01 Jun 2016 | BioXFEL Publications | Contributor(s): Che-Hsiung Hsu, Sangho Park, David E. Mortenson, B. Lachele Foley, Xiaocong Wang, Robert J. Woods, David Case, Evan T. Powers, Chi-Huey Wong, H. Jane Dyson, Jeffery W. Kelly

    http://dx.doi.org/10.1021/jacs.6b02879 journal-article Hsu, C.-H. et al., 2016. The Dependence of Carbohydrate–Aromatic Interaction Strengths on the Structure of the Carbohydrate. Journal of the …

    https://bioxfel.org/resources/2020

  4. Understanding nucleic acid structural changes by comparing wide-angle x-ray scattering (WAXS) experiments to molecular dynamics simulations

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    25 May 2016 | BioXFEL Publications | Contributor(s): Suzette A. Pabit, Andrea Katz, Igor S. Tolokh, Aleksander Drozdetski, Nathan Baker, Alexey V. Onufriev, Lois Pollack

    http://dx.doi.org/10.1063/1.4950814 journal-article Pabit, S.A. et al., 2016. Understanding nucleic acid structural changes by comparing wide-angle x-ray scattering (WAXS) experiments to molecular …

    https://bioxfel.org/resources/1384

  5. OnDA: online data analysis and feedback for serial X-ray imaging

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    24 May 2016 | BioXFEL Publications | Contributor(s): Valerio Mariani, Andrew Morgan, Chun Hong Yoon, Thomas J. Lane, Thomas A. White, Christopher O'Grady, Manuela Kuhn, Steve Aplin, Jason Koglin, Anton Barty, Henry Chapman

    This article describes a free and open-source data analysis utility designed for fast online feedback during serial X-ray diffraction and scattering experiments:OnDA(online data analysis). Three …

    https://bioxfel.org/resources/1208

  6. Liquid explosions induced by X-ray laser pulses

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    24 May 2016 | BioXFEL Publications | Contributor(s): Claudiu A. Stan, Despina Milathianaki, Hartawan Laksmono, Raymond G. Sierra, Trevor A. McQueen, Marc Messerschmidt, Garth J. Williams, Jason E. Koglin, Thomas J. Lane, Matt J. Hayes, Serge A. H. Guillet, Mengning Liang, Andrew L. Aquila, Philip R. Willmott, Joseph S. Robinson, Karl L. Gumerlock, Sabine Botha, Karol Nass, Ilme Schlichting, Robert L. Shoeman, Howard A. Stone, Sébastien Boutet

    http://dx.doi.org/10.1038/nphys3779 Claudiu A. Stan and Despina Milathianaki and Hartawan Laksmono and Raymond G. Sierra and Trevor A. McQueen and Marc Messerschmidt and Garth J. Williams and Jason …

    https://bioxfel.org/resources/1211

  7. Preprints for the life sciences

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    20 May 2016 | BioXFEL Publications | Contributor(s): J. M. Berg, N. Bhalla, P. E. Bourne, M. Chalfie, D. G. Drubin, J. S. Fraser, C. W. Greider, M. Hendricks, C. Jones, R. Kiley, S. King, M. W. Kirschner, H. M. Krumholz, R. Lehmann, M. Leptin, B. Pulverer, B. Rosenzweig, J. E. Spiro, M. Stebbins, C. Strasser, S. Swaminathan, P. Turner, R. D. Vale, K. VijayRaghavan, C. Wolberger

    http://dx.doi.org/10.1126/science.aaf9133 journal-article Berg, J.M. et al., 2016. Preprints for the life sciences. Science, 352(6288), pp.899–901. Available at: …

    https://bioxfel.org/resources/1457

  8. Expression and purification of an engineered human endothelin receptor B in a monomeric form

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    19 May 2016 | BioXFEL Publications | Contributor(s): A. V. Mishin, A. P. Luginina, A. P. Potapenko, V. I. Borshchevskiy, V. Katritch, E. Edelweiss, I. S. Okhrimenko, V. I. Gordeliy, V. G. Cherezov

    journal-article http://dx.doi.org/10.1134/s1607672916020216 Mishin, A.V. et al., 2016. Expression and purification of an engineered human endothelin receptor B in a monomeric form. Doklady …

    https://bioxfel.org/resources/1300

  9. Three-dimensional-printed gas dynamic virtual nozzles for x-ray laser sample delivery

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    18 May 2016 | BioXFEL Publications | Contributor(s): Garrett Charles Nelson, Richard Kirian, Uwe Weierstall, Nadia Zatsepin, Tomáš Faragó, Tilo Baumbach, Fabian Wilde, Fabian B. P. Niesler, Benjamin Zimmer, Izumi Ishigami, Masahide Hikita, Saša Bajt, Syun-Ru Yeh, Denis L. Rousseau, Henry Chapman, John Spence, Michael Heymann

    http://dx.doi.org/10.1364/oe.24.011515 Garrett Nelson and Richard A. Kirian and Uwe Weierstall and Nadia A. Zatsepin and Tomáš Faragó and Tilo Baumbach and Fabian Wilde and Fabian B. P. Niesler …

    https://bioxfel.org/resources/1106

  10. Imaging of Objects by Coherent Diffraction of X-Ray Free-Electron Laser Pulses

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    12 May 2016 | BioXFEL Publications | Contributor(s): Richard Kirian, Henry Chapman

    http://dx.doi.org/10.1007/978-3-319-14394-1_27 Richard A. Kirian and Henry N. Chapman Kirian, R.A. & Chapman, H.N., 2016. Imaging of Objects by Coherent Diffraction of X-Ray Free-Electron Laser …

    https://bioxfel.org/resources/1218

  11. Characterization of protein nanocrystals based on the reversibility of crystallization

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    10 May 2016 | BioXFEL Publications | Contributor(s): Katerina Dörner, Jose M. Martin-Garcia, Christopher Kupitz, Zhen Gong, T. Conn Mallet, Liqing Chen, Rebekka M. Wachter, Petra Fromme

    http://dx.doi.org/10.1021/acs.cgd.6b00384 Katerina Dörner and Jose M. Martin-Garcia and Christopher Kupitz and Zhen Gong and T. Conn Mallet and Liqing Chen and Rebekka M. Wachter and Petra Fromme …

    https://bioxfel.org/resources/923

  12. Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein

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    05 May 2016 | BioXFEL Publications | Contributor(s): K. Pande, C. D. M. Hutchison, G. Groenhof, A. Aquila, J. S. Robinson, J. Tenboer, S. Basu, S. Boutet, D. P. DePonte, M. Liang, T. A. White, N. A. Zatsepin, O. Yefanov, D. Morozov, D. Oberthuer, C. Gati, G. Subramanian, D. James, Y. Zhao, J. Koralek, J. Brayshaw, C. Kupitz, C. Conrad, S. Roy-Chowdhury, J. D. Coe, M. Metz, P. L. Xavier, T. D. Grant, J. E. Koglin, G. Ketawala, R. Fromme, V.  rajer, R. Henning, J. C. H. Spence, A. Ourmazd, P. Schwander, U. Weierstall, M. Frank, P. Fromme, A. Barty, H. N. Chapman, K. Moffat, J. J. Van Thor, M. Schmidt

    http://dx.doi.org/10.1126/science.aad5081 K. Pande and C. D. M. Hutchison and G. Groenhof and A. Aquila and J. S. Robinson and J. Tenboer and S. Basu and S. Boutet and D. P. DePonte and M. Liang and …

    https://bioxfel.org/resources/921

  13. Deterministic Absolute Negative Mobility for Micro- and Submicrometer Particles Induced in a Microfluidic Device

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    05 May 2016 | BioXFEL Publications | Contributor(s): Jinghui Luo, Katherine A. Muratore, Edgar A. Arriaga, Alexandra Ros

    http://dx.doi.org/10.1021/acs.analchem.6b00837 Jinghui Luo and Katherine A. Muratore and Edgar A. Arriaga and Alexandra Ros Luo, J. et al., 2016. Deterministic Absolute Negative Mobility for Micro- …

    https://bioxfel.org/resources/1217

  14. Review: Serial femtosecond crystallography: A revolution in structural biology

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    01 May 2016 | BioXFEL Publications | Contributor(s): Jose M. Martin-Garcia, Chelsie E Conrad, Jesse David Coe, Shatabdi Roy-Chowdhury, Petra Fromme

    http://dx.doi.org/10.1016/j.abb.2016.03.036 Jose M. Martin-Garcia and Chelsie E. Conrad and Jesse Coe and Shatabdi Roy-Chowdhury and Petra Fromme Martin-Garcia, J.M. et al., 2016. Serial femtosecond …

    https://bioxfel.org/resources/922

  15. Photocycle Populations with Femtosecond Excitation of Crystalline Photoactive Yellow Protein

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    01 May 2016 | BioXFEL Publications | Contributor(s): Christopher D.M. Hutchison, Marius Kaucikas, Jason Tenboer, Christopher Kupitz, Keith Moffat, Marius Schmidt, Jasper J. Van Thor

    http://dx.doi.org/10.1016/j.cplett.2016.04.087 Christopher D.M. Hutchison and Marius Kaucikas and Jason Tenboer and Christopher Kupitz and Keith Moffat and Marius Schmidt and Jasper J. van Thor …

    https://bioxfel.org/resources/919

  16. Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate

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    29 Apr 2016 | BioXFEL Publications | Contributor(s): Hongnan Cao, Kemin Tan, Fengbin Wang, Lance Bigelow, Ragothaman M. Yennamalli, Robert Jedrzejczak, Gyorgy Babnigg, Craig A. Bingman, Andrzej Joachimiak, Madan K. Kharel, Shanteri Singh, Jon S. Thorson, George Phillips

    http://dx.doi.org/10.1063/1.4948539 journal-article Cao, H. et al., 2016. Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking …

    https://bioxfel.org/resources/1385

  17. Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta

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    27 Apr 2016 | BioXFEL Publications | Contributor(s): Ray Yu-Ruei Wang, Yifan Song, Benjamin Barad, Yifan Cheng, James Fraser, Frank DiMaio

    http://dx.doi.org/10.1101/050286 Cryo-EM has revealed many challenging yet exciting macromolecular assemblies at near-atomic resolution (3-4.5 Angstrom), providing biological phenomena with molecular …

    https://bioxfel.org/resources/1366

  18. Dynamics from noisy data with extreme timing uncertainty

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    26 Apr 2016 | BioXFEL Publications | Contributor(s): R. Fung, A. Ourmazd, A. M. Hanna, O. Vendrell, S. Ramakrishna, T. Seideman, R. Santra

    http://dx.doi.org/10.1038/nature17627 R. Fung and A. Ourmazd and A. M. Hanna and O. Vendrell and S. Ramakrishna and T. Seideman and R. Santra and A. Ourmazd Fung, R. et al., 2016. Dynamics from noisy …

    https://bioxfel.org/resources/920

  19. Transmission electron microscopy for the evaluation and optimization of crystal growth

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    26 Apr 2016 | BioXFEL Publications | Contributor(s): Hilary P. Stevenson, Guowu Lin, Christopher Barnes, Ieva Sutkeviciute, Troy Krzysiak, Simon C. Weiss, Shelley Reynolds, Ying Wu, Veeranagu Nagarajan, Alexander M. Makhov, Robert M Lawrence, Emily Lamm, Lisa Clark, Timothy J. Gardella, Brenda Hogue, Craig M. Ogata, Jinwoo Ahn, Angela M. Gronenborn, James F. Conway, Jean-Pierre Vilardaga, Aina E. Cohen, Guillermo Calero

    The crystallization of protein samples remains the most significant challenge in structure determination by X-ray crystallography. Here, the effectiveness of transmission electron microscopy (TEM) …

    https://bioxfel.org/resources/1334

  20. Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting

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    25 Apr 2016 | BioXFEL Publications | Contributor(s): David Mavor, Kyle Barlow, Samuel Thompson, Benjamin A Barad, Alain R Bonny, Clinton L Cario, Garrett Gaskins, Zairan Liu, Laura Deming, Seth D Axen, Elena Caceres, Weilin Chen, Adolfo Cuesta, Rachel E Gate, Evan M Green, Kaitlin R Hulce, Weiyue Ji, Lillian R Kenner, Bruk Mensa, Leanna S Morinishi, Steven M Moss, Marco Mravic, Ryan K Muir, Stefan Niekamp, Chimno I Nnadi, Eugene Palovcak, Erin M Poss, Tyler D Ross, Eugenia C Salcedo, Stephanie K See, Meena Subramaniam, Allison W Wong, Jennifer Li, Kurt S Thorn, Shane Ó Conchúir, Benjamin P Roscoe, Eric D Chow, Joseph L DeRisi, Tanja Kortemme, Daniel N Bolon, James Fraser

    Ubiquitin is essential for eukaryotic life and varies in only 3 amino acid positions between yeast and humans. However, recent deep sequencing studies indicate that ubiquitin is highly tolerant to …

    https://bioxfel.org/resources/1201

  21. Multi-shell model of ion-induced nucleic acid condensation

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    21 Apr 2016 | BioXFEL Publications | Contributor(s): Igor S. Tolokh, Aleksander V. Drozdetski, Lois Pollack, Nathan A. Baker, Alexey V. Onufriev

    http://dx.doi.org/10.1063/1.4945382 journal-article Tolokh, I.S. et al., 2016. Multi-shell model of ion-induced nucleic acid condensation. The Journal of Chemical Physics, 144(15), p.155101. …

    https://bioxfel.org/resources/1386

  22. June 2016 Site Visit Agenda

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    21 Apr 2016 | Downloads

    …

    https://bioxfel.org/resources/918

  23. SAXS studies of RNA: structures, dynamics, and interactions with partners

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    12 Apr 2016 | BioXFEL Publications | Contributor(s): Yujie Chen, Lois Pollack

    http://dx.doi.org/10.1002/wrna.1349 Yujie Chen and Lois Pollack Chen, Y. & Pollack, L., 2016. SAXS studies of RNA: structures, dynamics, and interactions with partners. WIREs RNA. Available at: …

    https://bioxfel.org/resources/917

  24. X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex

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    11 Apr 2016 | BioXFEL Publications | Contributor(s): X. Edward Zhou, Xiang Gao, Anton Barty, Yanyong Kang, Yuanzheng He, Wei Liu, Andrii Ishchenko, Thomas A. White, Oleksandr Yefanov, Gye Won Han, Qingping Xu, Parker W. De Waal, Kelly M. Suino-Powell, Sébastien Boutet, Garth J. Williams, Meitian Wang, Dianfan Li, Martin Caffrey, Henry Chapman, John Spence, Petra Fromme, Uwe Weierstall, Raymond C. Stevens, Vadim Cherezov, Karsten Melcher, H. Eric Xu

    http://dx.doi.org/10.1038/sdata.2016.21 X. Edward Zhou and Xiang Gao and Anton Barty and Yanyong Kang and Yuanzheng He and Wei Liu and Andrii Ishchenko and Thomas A. White and Oleksandr Yefanov and …

    https://bioxfel.org/resources/1097

  25. Synthesis of Water-Soluble, Thiolate-Protected Gold Nanoparticles Uniform in Size

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    04 Apr 2016 | BioXFEL Publications | Contributor(s): Maia Azubel, Roger Kornberg

    journal-article http://dx.doi.org/10.1021/acs.nanolett.6b00981 Azubel, M. & Kornberg, R.D., 2016. Synthesis of Water-Soluble, Thiolate-Protected Gold Nanoparticles Uniform in Size. Nano Letters, …

    https://bioxfel.org/resources/1266

  26. Protein–DNA and ion–DNA interactions revealed through contrast variation SAXS

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    02 Apr 2016 | BioXFEL Publications | Contributor(s): Joshua M. Tokuda, Suzette A. Pabit, Lois Pollack

    http://dx.doi.org/10.1007/s12551-016-0196-8 journal-article Tokuda, J.M., Pabit, S.A. & Pollack, L., 2016. Protein–DNA and ion–DNA interactions revealed through contrast variation SAXS. …

    https://bioxfel.org/resources/1430

  27. Melatonin Receptors as Modulators of Methamphetamine-Mediated Behaviors

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    01 Apr 2016 | BioXFEL Publications | Contributor(s): Shannon J. Clough, Anthony J. Hutchinson, Margarita L. Dubocovich

    http://dx.doi.org/10.1016/b978-0-12-800212-4.00016-9 book-chapter Clough, S.J., Hutchinson, A.J. & Dubocovich, M.L., 2016. Melatonin Receptors as Modulators of Methamphetamine-Mediated Behaviors. …

    https://bioxfel.org/resources/1666

  28. 2016 Serial Crystallography Data Analysis Workshop at ACA Annual Meeting.

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    31 Mar 2016 | Workshops

    We are running a serial femtosecond crystallography data analysis workshop at ACA 2016 in Denver, CO, focused on "Serial Crystallography Data Analysis with Cheetah and CrystFEL: Concepts and …

    https://bioxfel.org/resources/2016-data-analysis-workshop

  29. Recent developments in CrystFEL

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    29 Mar 2016 | BioXFEL Publications | Contributor(s): Thomas A. White, Valerio Mariani, Wolfgang Brehm, Oleksandr Yefanov, Anton Barty, Kenneth R. Beyerlein, Fedor Chervinskii, Lorenzo Galli, Cornelius Gati, Takanori Nakane, Alexandra Tolstikova, Keitaro Yamashita, Chun Hong Yoon, Kay Diederichs, Henry Chapman

    CrystFELis a suite of programs for processing data from `serial crystallography' experiments, which are usually performed using X-ray free-electron lasers (FELs) but also increasingly with other …

    https://bioxfel.org/resources/950

  30. Measuring and modeling diffuse scattering in protein X-ray crystallography

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    28 Mar 2016 | BioXFEL Publications | Contributor(s): Andrew H. Van Benschoten, Lin Liu, Ana Gonzalez, Aaron S. Brewster, Nicholas K. Sauter, James Fraser, Michael E. Wall

    http://dx.doi.org/10.1073/pnas.1524048113 Andrew H. Van Benschoten and Lin Liu and Ana Gonzalez and Aaron S. Brewster and Nicholas K. Sauter and James S. Fraser and Michael E. Wall Van Benschoten, …

    https://bioxfel.org/resources/932

  31. Expression and Association of the Yersinia pestis Translocon Proteins, YopB and YopD, Are Facilitated by Nanolipoprotein Particles

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    25 Mar 2016 | BioXFEL Publications | Contributor(s): Matthew Coleman, Jenny A. Cappuccio, Craig D. Blanchette, Tingjuan Gao, Erin S. Arroyo, Angela K. Hinz, Feliza A. Bourguet, Brent W. Segelke, Paul D. Hoeprich, Thomas Huser, Ted A. Laurence, Vladimir L. Motin, Brett A. Chromy

    http://dx.doi.org/10.1371/journal.pone.0150166 Matthew A. Coleman and Jenny A. Cappuccio and Craig D. Blanchette and Tingjuan Gao and Erin S. Arroyo and Angela K. Hinz and Feliza A. Bourguet and …

    https://bioxfel.org/resources/978

  32. Immunological Characterization of Plant-Based HIV-1 Gag/Dgp41 Virus-Like Particles

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    17 Mar 2016 | BioXFEL Publications | Contributor(s): Sarah A. Kessans, Mark D. Linhart, Lydia R. Meador, Jacquelyn Kilbourne, Brenda Hogue, Petra Fromme, Nobuyuki Matoba, Tsafrir S. Mor

    http://dx.doi.org/10.1371/journal.pone.0151842 Sarah A. Kessans and Mark D. Linhart and Lydia R. Meador and Jacquelyn Kilbourne and Brenda G. Hogue and Petra Fromme and Nobuyuki Matoba and Tsafrir S. …

    https://bioxfel.org/resources/979

  33. Visualizing aerosol-particle injection for diffractive-imaging experiments

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    16 Mar 2016 | BioXFEL Publications | Contributor(s): Salah Awel, Richard Kirian, Niko Eckerskorn, Max Oliver Wiedorn, Daniel A. Horke, Andrei V. Rode, Jochen Küpper, Henry Chapman

    http://dx.doi.org/10.1364/oe.24.006507 Salah Awel and Richard A. Kirian and Niko Eckerskorn and Max Wiedorn and Daniel A. Horke and Andrei V. Rode and Jochen Küpper and Henry N. Chapman Awel, S. et …

    https://bioxfel.org/resources/972

  34. Anomalous Nonlinear X-ray Compton Scattering

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    14 Mar 2016 | BioXFEL Publications | Contributor(s): Matthias Fuchs

    proceedings-article http://dx.doi.org/10.1364/hilas.2016.hm3b.1 Fuchs, M., 2016. Anomalous Nonlinear X-ray Compton Scattering. High-Brightness Sources and Light-Driven Interactions. Available at: …

    https://bioxfel.org/resources/1303

  35. Data publication with the structural biology data grid supports live analysis

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    07 Mar 2016 | BioXFEL Publications | Contributor(s): Peter A. Meyer, Stephanie Socias, Jason Key, Elizabeth Ransey, Emily C. Tjon, Alejandro Buschiazzo, Ming Lei, Chris Botka, James Withrow, David Neau, Kanagalaghatta Rajashankar, Karen S. Anderson, Richard H. Baxter, Stephen C. Blacklow, Titus J. Boggon, Alexandre M. J. J. Bonvin, Dominika Borek, Tom J. Brett, Amedeo Caflisch, Chung-I Chang, Walter J. Chazin, Kevin D. Corbett, Michael S. Cosgrove, Sean Crosson, Sirano Dhe-Paganon, Enrico Di Cera, Catherine L. Drennan, Michael J. Eck, Brandt F. Eichman, Qing R. Fan, Adrian R. Ferré-D'Amaré, J. Christopher Fromme, K. Christopher Garcia, Rachelle Gaudet, Peng Gong, Stephen C. Harrison, Ekaterina E. Heldwein, Zongchao Jia, Robert J. Keenan, Andrew C. Kruse, Marc Kvansakul, Jason S. McLellan, Yorgo Modis, Yunsun Nam, Zbyszek Otwinowski, Emil F. Pai, Pedro José Barbosa Pereira, Carlo Petosa, C. S. Raman, Tom A. Rapoport, Antonina Roll-Mecak, Michael K. Rosen, Gabby Rudenko, Joseph Schlessinger, Thomas U. Schwartz, Yousif Shamoo, Holger Sondermann, Yizhi J. Tao, Niraj H. Tolia, Oleg V. Tsodikov, Kenneth D. Westover, Hao Wu, Ian Foster, James Fraser, Filipe R. N C. Maia, Tamir Gonen, Tom Kirchhausen, Kay Diederichs, Mercè Crosas, Piotr Sliz

    journal-article http://dx.doi.org/10.1038/ncomms10882 Meyer, P.A. et al., 2016. Data publication with the structural biology data grid supports live analysis. Nature Communications, 7, p.10882. …

    https://bioxfel.org/resources/1314

  36. Assessment of microcrystal quality by transmission electron microscopy for efficient serial femtosecond crystallography

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    02 Mar 2016 | BioXFEL Publications | Contributor(s): Christopher Barnes, Elena G. Kovaleva, Xiaofeng Fu, Hilary P. Stevenson, Aaron S. Brewster, Daniel P. DePonte, Elizabeth L. Baxter, Aina E. Cohen, Guillermo Calero

    journal-article http://dx.doi.org/10.1016/j.abb.2016.02.011 Barnes, C.O. et al., 2016. Assessment of microcrystal quality by transmission electron microscopy for efficient serial femtosecond …

    https://bioxfel.org/resources/1251

  37. AXSIS: Exploring the frontiers in attosecond X-ray science, imaging and spectroscopy

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    28 Feb 2016 | BioXFEL Publications | Contributor(s): F.X. Kärtner, F. Ahr, A.-L. Calendron, H. Çankaya, S. Carbajo, G. Chang, G. Cirmi, K. Dörner, U. Dorda, A. Fallahi, A. Hartin, M. Hemmer, R. Hobbs, Y. Hua, W.R. Huang, R. Letrun, N. Matlis, V. Mazalova, O.D. Mücke, E. Nanni, W. Putnam, K. Ravi, F. Reichert, I. Sarrou, X. Wu, A. Yahaghi, H. Ye, L. Zapata, D. Zhang, C. Zhou, R.J.D. Miller, K.K. Berggren, H. Graafsma, A. Meents, R.W. Assmann, H.N. Chapman, P. Fromme

    http://dx.doi.org/10.1016/j.nima.2016.02.080 F.X. Kärtner and F. Ahr and A.-L. Calendron and H. Çankaya and S. Carbajo and G. Chang and G. Cirmi and K. Dörner and U. Dorda and A. Fallahi and A. …

    https://bioxfel.org/resources/1081

  38. Protein Crystallization in an Actuated Microfluidic Nanowell Device

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    25 Feb 2016 | BioXFEL Publications | Contributor(s): Bahige G. Abdallah, Shatabdi Roy-Chowdhury, Raimund Fromme, Petra Fromme, Alexandra Ros

    http://dx.doi.org/10.1021/acs.cgd.5b01748 Bahige G. Abdallah and Shatabdi Roy-Chowdhury and Raimund Fromme and Petra Fromme and Alexandra Ros Abdallah, B.G. et al., 2016. Protein Crystallization in …

    https://bioxfel.org/resources/915

  39. Polyclonal Antibody Production for Membrane Proteins via Genetic Immunization

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    24 Feb 2016 | BioXFEL Publications | Contributor(s): Debra T. Hansen, Mark D. Robida, Felicia M. Craciunescu, Andrey V. Loskutov, Katerina Dörner, John-Charles Rodenberry, Xiao Wang, Tien L. Olson, Hetal Patel, Petra Fromme, Kathryn F. Sykes

    http://dx.doi.org/10.1038/srep21925 Debra T. Hansen and Mark D. Robida and Felicia M. Craciunescu and Andrey V. Loskutov and Katerina Dörner and John-Charles Rodenberry and Xiao Wang and Tien L. …

    https://bioxfel.org/resources/1099

  40. Reconstructing three-dimensional helical structure with an X-ray free electron laser

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    23 Feb 2016 | BioXFEL Publications | Contributor(s): M. Uddin

    Recovery of three-dimensional structure from single-particle X-ray scattering of completely randomly oriented diffraction patterns as predicted a few decades ago has been realized owing to the advent …

    https://bioxfel.org/resources/1295

  41. Loop dynamics of thymidine diphosphate-rhamnose 3′-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis

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    18 Feb 2016 | BioXFEL Publications | Contributor(s): Lu Han, Shanteri Singh, Jon S. Thorson, George Phillips

    http://dx.doi.org/10.1063/1.4941368 Lu Han and Shanteri Singh and Jon S. Thorson and George N. Phillips Han, L. et al., 2016. Loop dynamics of thymidine diphosphate-rhamnose 3′-O-methyltransferase …

    https://bioxfel.org/resources/929

  42. The Structural History of RNA Polymerase Transcription Machinery

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    18 Feb 2016 | Teaching Materials | Contributor(s): Roger Kornberg

    Dr. Roger Kornberg, 2006 Nobel Laureate in Chemistry, discusses the structural history of the RNA polymerase II transcription machinery and how it played a role in his successful career.

    https://bioxfel.org/resources/914

  43. Structural Studies of the Human Kappa Opioid Receptor Active State Conformations

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    16 Feb 2016 | BioXFEL Publications | Contributor(s): Ming-Yue Lee, Nilkanth N Patel, Vsevolod Katritch, Raymond C. Stevens, Vadim Cherezov

    http://dx.doi.org/10.1016/j.bpj.2015.11.275 Ming-Yue Lee and Nilkanth Patel and Vsevolod Katritch and Raymond C. Stevens and Vadim Cherezov Lee, M.-Y. et al., 2016. Structural Studies of the Human …

    https://bioxfel.org/resources/1077

  44. An in Vitro Investigation of Globin Folding and Expression

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    16 Feb 2016 | BioXFEL Publications | Contributor(s): Premila P. Samuel, William Ou, George Phillips, John S. Olson

    http://dx.doi.org/10.1016/j.bpj.2015.11.1166 journal-article Samuel, P.P. et al., 2016. An in Vitro Investigation of Globin Folding and Expression. Biophysical Journal, 110(3), p.209a–210a. …

    https://bioxfel.org/resources/1420

  45. Preparation and Delivery of Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography

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    16 Feb 2016 | BioXFEL Publications | Contributor(s): Andrii Ishchenko, Vadim Cherezov, Wei Liu

    http://dx.doi.org/10.1016/j.bpj.2015.11.383 Andrii Ishchenko and Vadim Cherezov and Wei Liu Ishchenko, A., Cherezov, V. & Liu, W., 2016. Preparation and Delivery of Microcrystals in Lipidic Cubic …

    https://bioxfel.org/resources/1078

  46. Continuous Changes in Structure Mapped by Manifold Embedding of Single-Particle Data in Cryo-EM

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    14 Feb 2016 | BioXFEL Publications | Contributor(s): Joachim Frank, Abbas Ourmazd

    http://dx.doi.org/10.1016/j.ymeth.2016.02.007 Joachim Frank and Abbas Ourmazd Frank, J. & Ourmazd, A., 2016. Continuous Changes in Structure Mapped by Manifold Embedding of Single-Particle Data in …

    https://bioxfel.org/resources/913

  47. Macromolecular diffractive imaging using imperfect crystals

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    10 Feb 2016 | BioXFEL Publications | Contributor(s): Kartik Ayyer, Oleksandr M. Yefanov, Dominik Oberthür, Shatabdi Roy-Chowdhury, Lorenzo Galli, Valerio Mariani, Shibom Basu, Jesse David Coe, Chelsie E Conrad, Raimund Fromme, Alexander Schaffer, Katerina Dörner, Daniel James, Christopher Kupitz, Markus Metz, Garrett Charles Nelson, Paulraj Lourdu Xavier, Kenneth R. Beyerlein, Marius Schmidt, Iosifina Sarrou, John Spence, Uwe Weierstall, Thomas A. White, Jay-How Yang, Yun Zhao, Mengning Liang, Andrew Aquila, Mark S. Hunter, Joseph S. Robinson, Jason E. Koglin, Sébastien Boutet, Petra Fromme, Anton Barty, Henry Chapman

    http://dx.doi.org/10.1038/nature16949 Kartik Ayyer and Oleksandr M. Yefanov and Dominik Oberthür and Shatabdi Roy-Chowdhury and Lorenzo Galli and Valerio Mariani and Shibom Basu and Jesse Coe and …

    https://bioxfel.org/resources/912

  48. Concentration of Sindbis virus with optimized gradient insulator-based dielectrophoresis

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    08 Feb 2016 | BioXFEL Publications | Contributor(s): Jie Ding, Robert M Lawrence, Paul V. Jones, Brenda Hogue, Mark A. Hayes

    http://dx.doi.org/10.1039/c5an02430g Jie Ding and Robert M. Lawrence and Paul V. Jones and Brenda G. Hogue and Mark A. Hayes Ding, J. et al., 2016. Concentration of Sindbis virus with optimized …

    https://bioxfel.org/resources/911

  49. CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites

    0.0 out of 5 stars 

    05 Feb 2016 | BioXFEL Publications | Contributor(s): Peter Cimermancic, Patrick Weinkam, T. Justin Rettenmaier, Leon Bichmann, Daniel A. Keedy, Rahel Woldeyes, Dina Schneidman-Duhovny, Omar N. Demerdash, Julie C. Mitchell, James A. Wells, James Fraser, Andrej Sali

    http://dx.doi.org/10.1016/j.jmb.2016.01.029 Peter Cimermancic and Patrick Weinkam and T. Justin Rettenmaier and Leon Bichmann and Daniel A. Keedy and Rahel A. Woldeyes and Dina Schneidman-Duhovny and …

    https://bioxfel.org/resources/910

  50. Transient lattice contraction in the solid-to-plasma transition

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    29 Jan 2016 | BioXFEL Publications | Contributor(s): Ken R. Ferguson, Maximilian Bucher, Tais Gorkhover, Sébastien Boutet, Hironobu Fukuzawa, Jason E. Koglin, Yoshiaki Kumagai, Alberto Lutman, Agostino Marinelli, Marc Messerschmidt, Kiyonobu Nagaya, Jim Turner, Kiyoshi Ueda, Garth J. Williams, Philip H. Bucksbaum, Christoph Bostedt

    http://dx.doi.org/10.1126/sciadv.1500837 Ken R. Ferguson and Maximilian Bucher and Tais Gorkhover and Sébastien Boutet and Hironobu Fukuzawa and Jason E. Koglin and Yoshiaki Kumagai and Alberto …

    https://bioxfel.org/resources/909

  51. One dimensional focusing with high numerical aperture multilayer Laue lens

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    28 Jan 2016 | BioXFEL Publications | Contributor(s): Saša Bajt, Mauro Prasciolu, Andrew J. Morgan, Henry Chapman, Jacek Krzywinski, Andrzej Andrejczuk

    http://dx.doi.org/10.1063/1.4937543 Saša Bajt and Mauro Prasciolu and Andrew J. Morgan and Henry N. Chapman and Jacek Krzywinski and Andrzej Andrejczuk Bajt, S. et al., 2016. One dimensional …

    https://bioxfel.org/resources/928

  52. Imaging of Objects by Coherent Diffraction of X-Ray Free-Electron Laser Pulses

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    28 Jan 2016 | BioXFEL Publications | Contributor(s): Richard Kirian, Henry Chapman

    http://dx.doi.org/10.1007/978-3-319-04507-8_27-2 Richard A. Kirian and Henry N. Chapman Kirian, R.A. & Chapman, H.N., 2015. Imaging of Objects by Coherent Diffraction of X-Ray Free-Electron Laser …

    https://bioxfel.org/resources/1070

  53. Femtosecond and nanometre visualization of structural dynamics in superheated nanoparticles

    0.0 out of 5 stars 

    25 Jan 2016 | BioXFEL Publications | Contributor(s): Tais Gorkhover, Sebastian Schorb, Ryan Coffee, Marcus Adolph, Lutz Foucar, Daniela Rupp, Andrew Aquila, John D. Bozek, Sascha W. Epp, Benjamin Erk, Lars Gumprecht, Lotte Holmegaard, Andreas Hartmann, Robert Hartmann, Günter Hauser, Peter Holl, Andre Hömke, Per Johnsson, Nils Kimmel, Kai-Uwe Kühnel, Marc Messerschmidt, Christian Reich, Arnaud Rouzée, Benedikt Rudek, Carlo Schmidt, Joachim Schulz, Heike Soltau, Stephan Stern, Georg Weidenspointner, Bill White, Jochen Küpper, Lothar Strüder, Ilme Schlichting, Joachim Ullrich, Daniel Rolles, Artem Rudenko, Thomas Möller, Christoph Bostedt

    http://dx.doi.org/10.1038/nphoton.2015.264 Tais Gorkhover and Sebastian Schorb and Ryan Coffee and Marcus Adolph and Lutz Foucar and Daniela Rupp and Andrew Aquila and John D. Bozek and Sascha W. Epp …

    https://bioxfel.org/resources/908

  54. Melatonin receptor activation increases glutamatergic synaptic transmission in the rat medial lateral habenula

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    22 Jan 2016 | BioXFEL Publications | Contributor(s): Katherine M. Evely, Randall L. Hudson, Margarita L. Dubocovich, Samir Haj-dahmane

    http://dx.doi.org/10.1002/syn.21892 journal-article Evely, K.M. et al., 2016. Melatonin receptor activation increases glutamatergic synaptic transmission in the rat medial lateral habenula. …

    https://bioxfel.org/resources/1667

  55. Serial femtosecond crystallography opens new avenues for Structural Biology

    0.0 out of 5 stars 

    20 Jan 2016 | BioXFEL Publications | Contributor(s): Jesse David Coe, Petra Fromme

    http://dx.doi.org/10.2174/0929866523666160120152937 Jesse Coe and Petra Fromme Coe, J. & Fromme, P., 2016. Serial femtosecond crystallography opens new avenues for Structural Biology. PPL, 23(3), …

    https://bioxfel.org/resources/981

  56. The Role of Correlation and Solvation in Ion Interactions with B-DNA

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    19 Jan 2016 | BioXFEL Publications | Contributor(s): Maria L. Sushko, Dennis G. Thomas, Suzette A. Pabit, Lois Pollack, Alexey V. Onufriev, Nathan A. Baker

    journal-article http://dx.doi.org/10.1016/j.bpj.2015.12.011 Sushko, M.L. et al., 2016. The Role of Correlation and Solvation in Ion Interactions with B-DNA. Biophysical Journal, 110(2), …

    https://bioxfel.org/resources/1306

  57. In cellulo serial crystallography of alcohol oxidase crystals inside yeast cells

    0.0 out of 5 stars 

    11 Jan 2016 | BioXFEL Publications | Contributor(s): Arjen J. Jakobi, Daniel M. Passon, Kèvin Knoops, Francesco Stellato, Mengning Liang, Thomas A. White, Thomas Seine, Marc Messerschmidt, Henry Chapman, Matthias Wilmanns

    The possibility of using femtosecond pulses from an X-ray free-electron laser to collect diffraction data from protein crystals formed in their native cellular organelle has been explored. X-ray …

    https://bioxfel.org/resources/907

  58. Computational crystallization

    0.0 out of 5 stars 

    11 Jan 2016 | BioXFEL Publications | Contributor(s): Irem Altan, Patrick Charbonneau, Edward Snell

    http://dx.doi.org/10.1016/j.abb.2016.01.004 Irem Altan and Patrick Charbonneau and Edward H. Snell Altan, I., Charbonneau, P. & Snell, E.H., 2016. Computational crystallization. Archives of …

    https://bioxfel.org/resources/1076

  59. Serial femtosecond crystallography on in vivo grown crystals at SACLA - developments and results

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Leonard M. G. Chavas, Sasa Bajt, Lars Gumprecht, Henry Chapman

    http://dx.doi.org/10.1107/s2053273315097831 Leonard M. G. Chavas and Sasa Bajt and Lars Gumprecht and Henry N. Chapman Chavas, L.M.G. et al., 2015. Serial femtosecond crystallography on in vivo …

    https://bioxfel.org/resources/959

  60. Towards a generalised approach for the time-resolved crystallographic study of enzymes

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Diana C. F. Monteiro, Vijay Patel, Christopher P. Bartlett, Shingo Nozaki, Thomas D. Grant, James A. Gowdy, Gary S. Thompson, Arnout P. Kalverda, Edward Snell, Hironori Niki, Arwen R. Pearson, Michael E. Webb

    http://dx.doi.org/10.1107/s205327331509957x Diana C. F. Monteiro and Vijay Patel and Christopher P. Bartlett and Shingo Nozaki and Thomas D. Grant and James A. Gowdy and Gary S. Thompson and Arnout …

    https://bioxfel.org/resources/960

  61. Phase retrieval for randomly terminated finite crystals

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Joe Chen, Rick A. Kirian, Richard J. Bean, Kenneth R. Beyerlein, Miriam Barthelmess, Chun Hong Yoon, Fenglin Wang, Flavio Capotondi, Emanuele Pedersoli, Anton Barty, Henry Chapman, Philip J. Bones, Romain D. Arnal, Rick P. Millane, John Spence

    http://dx.doi.org/10.1107/s2053273315099714 Joe P. J. Chen and Rick A. Kirian and Richard J. Bean and Kenneth R. Beyerlein and Miriam Barthelmess and Chun Hong Yoon and Fenglin Wang and Flavio …

    https://bioxfel.org/resources/961

  62. Improving resolution in serial crystallography

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Kartik Ayyer, Oleksandr M. Yefanov, Dominik Oberthuer, Shatabdi Roy Chowdhury, Lorenzo Galli, Valerio Mariani, Shibom Basu, Jesse David Coe, Chelsie E Conrad, Raimund Fromme, Katerina Doerner, Matthias Frank, Daniel James, Christopher Kupitz, Markus Metz, Garrett Charles Nelson, Xavier L. Paulraj, Kenneth Beyerlein, Marius Schmidt, Iosifina Sarrou, John Spence, Uwe Weierstall, Thomas A. White, Jayhow Yang, Nadia Zatsepin, Yun Zhao, Mengning Liang, Andrew Aquila, Mark S. Hunter, Joseph S. Robinson, Jason E. Koglin, Sébastien Boutet, Petra Fromme, Anton Barty, Henry Chapman

    http://dx.doi.org/10.1107/s2053273315099738 Kartik Ayyer and Oleksandr M. Yefanov and Dominik Oberthuer and Shatabdi Chowdhury and Lorenzo Galli and Valerio Mariani and Shibom Basu and Jesse Coe and …

    https://bioxfel.org/resources/962

  63. Serial synchrotron crystallography experiments at EMBL beamline P14 at PETRA III

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Thomas R. Schneider, Gleb Bourenkov, Cornelius Gati, Henry Chapman, Lars Redecke, Ulrich Zander, José A. Marquez, Florent Cipriani

    http://dx.doi.org/10.1107/s2053273315099805 Thomas R. Schneider and Gleb Bourenkov and Cornelius Gati and Henry N. Chapman and Lars Redecke and Ulrich Zander and José A. Marquez and Florent Cipriani …

    https://bioxfel.org/resources/963

  64. Interview with Dilano Saldin

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    05 Jan 2016 | Teaching Materials

    Combining data from new facilities with mathematical methods, Professor Dilano Saldin is in pursuit of a technique to determine the structure of molecules without the need for purification …

    https://bioxfel.org/resources/868

  65. Ternary structure reveals mechanism of a membrane diacylglycerol kinase

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    17 Dec 2015 | BioXFEL Publications | Contributor(s): Dianfan Li, Phillip J. Stansfeld, Mark S. P. Sansom, Aaron Keogh, Lutz Vogeley, Nicole Howe, Joseph A. Lyons, David Aragao, Petra Fromme, Raimund Fromme, Shibom Basu, Ingo Grotjohann, Christopher Kupitz, Kimberley Rendek, Uwe Weierstall, Nadia Zatsepin, Vadim Cherezov, Wei Liu, Sateesh Bandaru, Niall J. English, Cornelius Gati, Anton Barty, Oleksandr Yefanov, Henry Chapman, Kay Diederichs, Marc Messerschmidt, Sébastien Boutet, Garth J. Williams, M. Marvin Seibert, Martin Caffrey

    http://dx.doi.org/10.1038/ncomms10140 Dianfan Li and Phillip J. Stansfeld and Mark S. P. Sansom and Aaron Keogh and Lutz Vogeley and Nicole Howe and Joseph A. Lyons and David Aragao and Petra Fromme …

    https://bioxfel.org/resources/881

  66. Tuning RNA Flexibility with Helix Length and Junction Sequence

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    15 Dec 2015 | BioXFEL Publications | Contributor(s): Julie L. Sutton, Lois Pollack

    http://dx.doi.org/10.1016/j.bpj.2015.10.039 journal-article Sutton, J.L. & Pollack, L., 2015. Tuning RNA Flexibility with Helix Length and Junction Sequence. Biophysical Journal, 109(12), …

    https://bioxfel.org/resources/1421

  67. Optically Induced Forces Imposed in an Optical Funnel on a Stream of Particles in Air or Vacuum

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    11 Dec 2015 | BioXFEL Publications | Contributor(s): Niko Eckerskorn, Richard Bowman, Richard Kirian, Salah Awel, Max Oliver Wiedorn, Jochen Küpper, Miles J. Padgett, Henry Chapman, Andrei V. Rode

    http://dx.doi.org/10.1103/physrevapplied.4.064001 Niko Eckerskorn and Richard Bowman and Richard A. Kirian and Salah Awel and Max Wiedorn and Jochen Küpper and Miles J. Padgett and Henry N. Chapman …

    https://bioxfel.org/resources/872

  68. Time-Resolved Crystallography at X-ray Free Electron Lasers and Synchrotron Light Sources

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    09 Dec 2015 | BioXFEL Publications | Contributor(s): Marius Schmidt

    http://dx.doi.org/10.1080/08940886.2015.1101324 Marius Schmidt Schmidt, M., 2015. Time-Resolved Crystallography at X-ray Free Electron Lasers and Synchrotron Light Sources. Synchrotron Radiation …

    https://bioxfel.org/resources/886

  69. Ceramic micro-injection molded nozzles for serial femtosecond crystallography sample delivery

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    09 Dec 2015 | BioXFEL Publications | Contributor(s): K. R. Beyerlein, L. Adriano, M. Heymann, R. Kirian, J. Knoška, F. Wilde, H. N. Chapman, S. Bajt

    http://dx.doi.org/10.1063/1.4936843 K. R. Beyerlein and L. Adriano and M. Heymann and R. Kirian and J. Knoška and F. Wilde and H. N. Chapman and S. Bajt Beyerlein, K.R. et al., 2015. Ceramic …

    https://bioxfel.org/resources/927

  70. Measuring and modeling diffuse scattering in protein X-ray crystallography

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    07 Dec 2015 | BioXFEL Publications | Contributor(s): Andrew H Van Benschoten, Lin Liu, Ana Gonzalez, Aaron S Brewster, Nicholas K Sauter, James Fraser, Michael Wall

    X-ray diffraction has the potential to provide rich information about the structural dynamics of macromolecules. To realize this potential, both Bragg scattering, which is currently used to derive …

    https://bioxfel.org/resources/944

  71. The Fragment Molecular Orbital Method Reveals New Insight into the Chemical Nature of GPCR–Ligand Interactions

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    07 Dec 2015 | BioXFEL Publications | Contributor(s): Alexander Heifetz, Ewa I. Chudyk, Laura Gleave, Matteo Aldeghi, Vadim Cherezov, Dmitri G. Fedorov, Philip C. Biggin, Mike J. Bodkin

    http://dx.doi.org/10.1021/acs.jcim.5b00644 Alexander Heifetz and Ewa I. Chudyk and Laura Gleave and Matteo Aldeghi and Vadim Cherezov and Dmitri G. Fedorov and Philip C. Biggin and Mike J. Bodkin …

    https://bioxfel.org/resources/1223

  72. Multitemperature data and diffuse scattering in X-ray crystallography

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    07 Dec 2015 | Teaching Materials | Contributor(s): James Fraser

    Dr. James Fraser will discuss recent advances in mapping the structural basis of protein conformational dynamics using multitemperature data and diffuse scattering from both conventional synchrotron …

    https://bioxfel.org/resources/865

  73. Structural Basis of Stereospecificity in the Bacterial Enzymatic Cleavage of β-Aryl Ether Bonds in Lignin

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    04 Dec 2015 | BioXFEL Publications | Contributor(s): Kate E. Helmich, Jose Henrique Pereira, Daniel L. Gall, Richard A. Heins, Ryan P. McAndrew, Craig Bingman, Kai Deng, Keefe C. Holland, Daniel R. Noguera, Blake A. Simmons, Kenneth L. Sale, John Ralph, Timothy J. Donohue, Paul D. Adams, George Phillips

    http://dx.doi.org/10.1074/jbc.m115.694307 Kate E. Helmich and Jose Henrique Pereira and Daniel L. Gall and Richard A. Heins and Ryan P. McAndrew and Craig Bingman and Kai Deng and Keefe C. Holland …

    https://bioxfel.org/resources/935

  74. High-density grids for efficient data collection from multiple crystals

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    03 Dec 2015 | BioXFEL Publications | Contributor(s): Elizabeth L. Baxter, Laura Aguila, Roberto Alonso-Mori, Christopher Barnes, Christopher A. Bonagura, Winnie Brehmer, Axel T. Brunger, Guillermo Calero, Tom T. Caradoc-Davies, Ruchira Chatterjee, William F. Degrado, James Fraser, Mohamed Ibrahim, Jan Kern, Brian K. Kobilka, Andrew C. Kruse, Karl M. Larsson, Heinrik T. Lemke, Artem Y. Lyubimov, Aashish Manglik, Scott E. McPhillips, Erik Norgren, Siew S. Pang, S. M. Soltis, Jinhu Song, Jessica Thomaston, Yingssu Tsai, William I. Weis, Rahel Woldeyes, Vittal Yachandra, Junko Yano, Athina Zouni, Aina E. Cohen

    Higher throughput methods to mount and collect data from multiple small and radiation-sensitive crystals are important to support challenging structural investigations using microfocus synchrotron …

    https://bioxfel.org/resources/893

  75. Concentric-flow electrokinetic injector enables serial crystallography of ribosome and photosystem II

    0.0 out of 5 stars 

    30 Nov 2015 | BioXFEL Publications | Contributor(s): Raymond G Sierra, Cornelius Gati, Hartawan Laksmono, E Han Dao, Sheraz Gul, Franklin Fuller, Jan Kern, Ruchira Chatterjee, Mohamed Ibrahim, Aaron S Brewster, Iris Diane Young, Tara Michels-Clark, Andrew Aquila, Mengning Liang, Mark S. Hunter, Jason E Koglin, Sébastien Boutet, Elia A Junco, Brandon Hayes, Michael J Bogan, Christina Y Hampton, Elisabetta V Puglisi, Nicholas K Sauter, Claudiu A Stan, Athina Zouni, Junko Yano, Vittal K Yachandra, S Michael Soltis, Joseph D Puglisi, Hasan Demirci

    http://dx.doi.org/10.1038/nmeth.3667 Raymond G Sierra and Cornelius Gati and Hartawan Laksmono and E Han Dao and Sheraz Gul and Franklin Fuller and Jan Kern and Ruchira Chatterjee and Mohamed Ibrahim …

    https://bioxfel.org/resources/1095

  76. XFELs open a new era in structural chemical biology

    0.0 out of 5 stars 

    17 Nov 2015 | BioXFEL Publications | Contributor(s): Petra Fromme

    http://dx.doi.org/10.1038/nchembio.1968 Petra Fromme Fromme, P., 2015. XFELs open a new era in structural chemical biology. Nat Chem Biol, 11(12), pp.895–899. Available at: …

    https://bioxfel.org/resources/875

  77. Polarizability of Six-Helix Bundle and Triangle DNA Origami and Their Escape Characteristics from a Dielectrophoretic Trap

    0.0 out of 5 stars 

    16 Nov 2015 | BioXFEL Publications | Contributor(s): Lin Gan, Fernanda Camacho-Alanis, Alexandra Ros

    http://dx.doi.org/10.1021/acs.analchem.5b02524 Lin Gan and Fernanda Camacho-Alanis and Alexandra Ros Gan, L., Camacho-Alanis, F. & Ros, A., 2015. Polarizability of Six-Helix Bundle and Triangle DNA …

    https://bioxfel.org/resources/1086

  78. BioXFEL Graduate Student Cross-Training Scholarship

    0.0 out of 5 stars 

    11 Nov 2015 | Teaching Materials

    BioXFEL is committed to providing our students with opportunities to diversify their skill sets and integrate themselves into our highly multidisciplinary Center. In addition to the workshops, …

    https://bioxfel.org/resources/CTS

  79. BioXFEL Scholar Application Form

    0.0 out of 5 stars 

    10 Nov 2015 | Teaching Materials

    …

    https://bioxfel.org/resources/658

  80. Serial femtosecond crystallography of soluble proteins in lipidic cubic phase

    0.0 out of 5 stars 

    10 Nov 2015 | Teaching Materials

    Serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs) enables high-resolution protein structure determination using micrometre-sized crystals at room temperature with minimal …

    https://bioxfel.org/resources/681

  81. Indexing ambiguity in SFX resolved using expectation maximization algorithm

    0.0 out of 5 stars 

    10 Nov 2015 | Teaching Materials

    Crystallographic auto-indexing algorithms provide crystal orientations and unit-cell parameters and assign Miller indices based on the geometric relations between the Bragg peaks observed in …

    https://bioxfel.org/resources/680

  82. Stable Chromosome Condensation Revealed by Chromosome Conformation Capture

    0.0 out of 5 stars 

    05 Nov 2015 | BioXFEL Publications | Contributor(s): Kyle P. Eagen, Tom A. Hartl, Roger D. Kornberg

    journal-article http://dx.doi.org/10.1016/j.cell.2015.10.026 Eagen, K.P., Hartl, T.A. & Kornberg, R.D., 2015. Stable Chromosome Condensation Revealed by Chromosome Conformation Capture. Cell, …

    https://bioxfel.org/resources/1256

  83. Chromatin-remodeling and the initiation of transcription

    0.0 out of 5 stars 

    05 Nov 2015 | BioXFEL Publications | Contributor(s): Yahli Lorch, Roger Kornberg

    http://dx.doi.org/10.1017/s0033583515000116 AbstractThe nucleosome serves as a general gene repressor by the occlusion of regulatory and promoter DNA sequences. Repression is relieved by the …

    https://bioxfel.org/resources/1449

  84. Introduction to XRayView Crystallographic Software

    0.0 out of 5 stars 

    04 Nov 2015 | Teaching Materials

    Dr. George Phillips introduces the basic concepts of crystallography focusing on the reciprocal lattice and Ewald sphere construction and using the XRayView software developed in his lab to help …

    https://bioxfel.org/resources/679

  85. The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor

    0.0 out of 5 stars 

    03 Nov 2015 | BioXFEL Publications | Contributor(s): Rebecca L. Miller, Aaron A. Thompson, Claudio Trapella, Remo Guerrini, Davide Malfacini, Nilkanth N Patel, Gye Won Han, Vadim Cherezov, Girolamo Caló, Vsevolod Katritch, Raymond C. Stevens

    http://dx.doi.org/10.1016/j.str.2015.07.024 Rebecca L. Miller and Aaron A. Thompson and Claudio Trapella and Remo Guerrini and Davide Malfacini and Nilkanth Patel and Gye Won Han and Vadim Cherezov …

    https://bioxfel.org/resources/1084

  86. High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction

    0.0 out of 5 stars 

    02 Nov 2015 | BioXFEL Publications | Contributor(s): Jessica L. Thomaston, Mercedes Alfonso-Prieto, Rahel Woldeyes, James Fraser, Michael L. Klein, Giacomo Fiorin, William F. DeGrado

    http://dx.doi.org/10.1073/pnas.1518493112 Jessica L. Thomaston and Mercedes Alfonso-Prieto and Rahel A. Woldeyes and James S. Fraser and Michael L. Klein and Giacomo Fiorin and William F. DeGrado …

    https://bioxfel.org/resources/860

  87. Nucleation and Growth of Membrane Protein CrystalsIn Meso—A Fluorescence Microscopy Study

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    02 Nov 2015 | BioXFEL Publications | Contributor(s): Andrey Bogorodskiy, Fedor Frolov, Alexey Mishin, Ekaterina Round, Vitaly Polovinkin, Vadim Cherezov, Valentin Gordeliy, Georg Büldt, Thomas Gensch, Valentin Borshchevskiy

    journal-article http://dx.doi.org/10.1021/acs.cgd.5b01061 Bogorodskiy, A. et al., 2015. Nucleation and Growth of Membrane Protein CrystalsIn Meso—A Fluorescence Microscopy Study. Crystal Growth & …

    https://bioxfel.org/resources/1265

  88. Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892

    0.0 out of 5 stars 

    29 Oct 2015 | BioXFEL Publications | Contributor(s): Jeffrey D. Rudolf, Lance Bigelow, Changsoo Chang, Marianne E. Cuff, Jeremy R. Lohman, Chin-Yuan Chang, Ming Ma, Dong Yang, Shonda Clancy, Gyorgy Babnigg, Andrzej Joachimiak, George Phillips, Ben Shen

    http://dx.doi.org/10.1021/acs.biochem.5b01008 Jeffrey D. Rudolf and Lance Bigelow and Changsoo Chang and Marianne E. Cuff and Jeremy R. Lohman and Chin-Yuan Chang and Ming Ma and Dong Yang and Shonda …

    https://bioxfel.org/resources/1087

  89. Exposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using qFit

    0.0 out of 5 stars 

    27 Oct 2015 | BioXFEL Publications | Contributor(s): Daniel A. Keedy, James Fraser, Henry Van Den Bedem

    http://dx.doi.org/10.1371/journal.pcbi.1004507 Daniel A. Keedy and James S. Fraser and Henry van den Bedem Keedy, D.A., Fraser, J.S. & van den Bedem, H., 2015. Exposing Hidden Alternative Backbone …

    https://bioxfel.org/resources/975

  90. Accurate determination of segmented X-ray detector geometry

    0.0 out of 5 stars 

    22 Oct 2015 | BioXFEL Publications | Contributor(s): Oleksandr Yefanov, Valerio Mariani, Cornelius Gati, Thomas A. White, Henry Chapman, Anton Barty

    http://dx.doi.org/10.1364/oe.23.028459 Oleksandr Yefanov and Valerio Mariani and Cornelius Gati and Thomas A. White and Henry N. Chapman and Anton Barty Yefanov, O. et al., 2015. Accurate …

    https://bioxfel.org/resources/861

  91. Structure of an RNA polymerase II preinitiation complex

    0.0 out of 5 stars 

    20 Oct 2015 | BioXFEL Publications | Contributor(s): Kenji Murakami, Kuang-Lei Tsai, Nir Kalisman, David Bushnell, Francisco J. Asturias, Roger Kornberg

    journal-article http://dx.doi.org/10.1073/pnas.1518255112 Murakami, K. et al., 2015. Structure of an RNA polymerase II preinitiation complex. Proceedings of the National Academy of Sciences, …

    https://bioxfel.org/resources/1323

  92. Overview of Serial Femtosecond Crystallography

    0.0 out of 5 stars 

    14 Oct 2015 | Teaching Materials | Contributor(s): Petra Fromme

    Dr. Petra Fromme discusses an introductory overview to the field of serial crystallography and recent results showing the potential power of the technique.

    https://bioxfel.org/resources/668

  93. Virus Crystallography

    0.0 out of 5 stars 

    14 Oct 2015 | Teaching Materials | Contributor(s): Robert M Lawrence

    Dr. Rob Lawrence describes the unique problems associated with crystallization of virus particles and different methods to overcome them.

    https://bioxfel.org/resources/667

  94. When Your Crystals Bite

    0.0 out of 5 stars 

    14 Oct 2015 | Teaching Materials | Contributor(s): George Phillips

    Dr. George Phillips describes properties of crystals such as twinning and other defects and how they can adversely affect crystallographic analysis.

    https://bioxfel.org/resources/666

  95. Optimizing crystallization hits - small to large and large to small

    0.0 out of 5 stars 

    14 Oct 2015 | Teaching Materials | Contributor(s): Joseph Luft

    Joe Luft describes methods for optimizing initial results from crystallization screening trials for both macro and nanocrystals.

    https://bioxfel.org/resources/665

  96. Practical Considerations for Crystallographic Data Analysis

    0.0 out of 5 stars 

    14 Oct 2015 | Teaching Materials | Contributor(s): Tom Grant

    Dr. Thomas Grant explains how crystal quality affects diffraction data and how you can detect and ameliorate problems in crystallographic data.

    https://bioxfel.org/resources/664

  97. Applications of TEM for Evaluation and Optimization of Crystal Growth

    0.0 out of 5 stars 

    14 Oct 2015 | Teaching Materials | Contributor(s): Guillermo Calero

    Dr. Guillero Calero discusses using transmission electron microscopy to characterize, evaluate and subsequently optimize the growth of crystals.

    https://bioxfel.org/resources/663

  98. What is the outcome of your crystallization experiment

    0.0 out of 5 stars 

    14 Oct 2015 | Teaching Materials | Contributor(s): Joseph Luft

    Joe Luft discusses the detection of hits in crystallization screening experiments for both macro and nanocrystals.

    https://bioxfel.org/resources/662

  99. Strategies to sample crystallization space

    0.0 out of 5 stars 

    14 Oct 2015 | Teaching Materials | Contributor(s): Joseph Luft

    Joe Luft discusses crystallization screening strategies to maximize the likelihood of success.

    https://bioxfel.org/resources/661

  100. Fundamentals of Crystal Growth

    0.0 out of 5 stars 

    14 Oct 2015 | Teaching Materials | Contributor(s): Edward Snell, Eaton E Lattman

    Dr. Ed Lattman discusses the foundations of crystallography and theoretical and practical considerations including X-ray radiation and production and crystallization nucleation, growth and …

    https://bioxfel.org/resources/660

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