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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): J. E. Koglin, T. R. Barends, R. L. Shoeman, L. Foucar, I. Schlichting, S. Boutet, R. B. Doak, K. Nass, G. J. Williams, S. Botha, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): M. Caffrey, R. A. Kirian, S. Boutet, D. Wang, I. Grotjohann, C. Wang, A. Barty, T. A. White, K. R. Beyerlein, G. W. Han, S. Basu, D. Wacker, C. Gati, V. Katritch, M. M. Seibert, S. T. Shah, K. N. Rendek, G. J. Williams, R. C. Stevens, J. E. Koglin, W. Liu, N. A. Zatsepin, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): G. Schaller, S. Bajt, D. P. DePonte, N. Timneanu, B. Erk, M. M. Seibert, I. Grotjohann, T. A. White, G. Hauser, L. Gumprecht, J. Krzywinski, A. Rocker, M. Bott, H. Soltau, S. Stern, F. Krasniqi, R. Andritschke, R. Hartmann, C. D. Schroter, L. Struder, H. Gorke, S. Herrmann, D. Rolles, P. Holl, K. Nass, B. Rudek, J. Andreasson, A. Aquila, T. R. Barends, G. Potdevin, R. Neutze, C. Y. Hampton, N. Kimmel, J. Ullrich, A. V. Martin, M. Liang, I. Andersson, F. Schopper, J. Hajdu, A. Homke, X. Wang, M. Barthelmess, H. Hirsemann, S. Schorb, D. Starodub, R. A. Kirian, L. Foucar, R. G. Sierra, C. Caleman, G. Weidenspointner, S. Boutet, D. Pietschner, O. Jonsson, B. Nilsson, M. Svenda, I. Schlichting, T. Gorkhover, L. Lomb, N. Coppola, J. Schulz, A. Rudenko, M. J. Bogan, S. W. Epp, F. R. Maia, R. B. Doak, G. J. Williams, R. L. Shoeman, C. Reich, J. D. Bozek, A. Barty, M. Adolph, H. Graafsma, S. Marchesini, D. Rupp, K. U. Kuhnel, C. Bostedt, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): R. L. Shoeman, G. Schaller, D. P. DePonte, M. Hantke, J. Ullrich, B. Rudek, K. U. Kuhnel, I. Andersson, A. Barty, C. Reich, V. Seltzer, M. Adolph, J. Krzywinski, B. Erk, S. Schorb, H. Hirsemann, R. G. Sierra, F. Schopper, L. Gumprecht, J. Andreasson, A. Martin, S. Boutet, N. Kimmel, G. Williams, D. Rolles, M. Liang, D. Westphal, C. Bostedt, T. Ekeberg, R. Kirian, G. Potdevin, D. Odic, M. Bott, J. Schulz, B. Nilsson, S. W. Epp, K. O. Hodgson, A. Aquila, L. Struder, J. Hajdu, A. Rudenko, S. Marchesini, P. Holl, H. Graafsma, D. Starodub, R. B. Doak, M. Svenda, F. R. Maia, C. D. Schroter, I. Schlichting, A. Homke, S. Bajt, N. Coppola, G. Weidenspointner, D. Pietschner, M. J. Bogan, C. Abergel, T. A. White, L. Foucar, G. Hauser, C. Y. Hampton, M. Barthelmess, J. M. Claverie, B. Iwan, S. Stern, H. Soltau, A. A. Miahnahri, R. Hartmann, T. Gorkhover, L. Lomb, J. D. Bozek, A. Rocker, S. Herrmann, O. Jonsson, H. Gorke, D. Rupp, R. Andritschke, M. M. Seibert, F. Krasniqi, C. Caleman, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://bioxfel.org/resources/294
