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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, S. Boutet, I. Schlichting, R. B. Doak, K. Nass, S. Botha, G. J. Williams, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): S. Boutet, D. Wacker, C. Gati, M. M. Seibert, G. J. Williams, K. N. Rendek, T. A. White, N. A. Zatsepin, J. E. Koglin, S. Basu, M. Caffrey, V. Katritch, R. A. Kirian, S. T. Shah, D. Wang, W. Liu, I. Grotjohann, R. C. Stevens, C. Wang, G. W. Han, A. Barty, K. R. Beyerlein, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): X. Wang, J. Andreasson, S. Schorb, H. Gorke, R. G. Sierra, K. Nass, M. Barthelmess, F. R. Maia, R. A. Kirian, C. Reich, A. Rudenko, S. Boutet, G. Potdevin, J. Ullrich, T. Gorkhover, I. Andersson, D. Rupp, O. Jonsson, C. Bostedt, M. Svenda, A. Barty, L. Lomb, L. Foucar, J. Hajdu, S. W. Epp, H. Hirsemann, R. L. Shoeman, B. Erk, M. J. Bogan, G. Hauser, R. B. Doak, D. P. DePonte, N. Coppola, I. Schlichting, S. Marchesini, G. Weidenspointner, F. Krasniqi, C. D. Schroter, A. Rocker, M. Adolph, G. J. Williams, J. Schulz, T. A. White, S. Bajt, D. Rolles, N. Timneanu, B. Rudek, M. M. Seibert, A. Aquila, L. Gumprecht, J. D. Bozek, S. Stern, H. Graafsma, R. Hartmann, K. U. Kuhnel, A. V. Martin, M. Bott, F. Schopper, R. Andritschke, C. Y. Hampton, I. Grotjohann, S. Herrmann, G. Schaller, T. R. Barends, D. Starodub, P. Holl, C. Caleman, A. Homke, L. Struder, J. Krzywinski, H. Soltau, R. Neutze, B. Nilsson, M. Liang, D. Pietschner, N. Kimmel, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): R. Kirian, D. Rupp, N. Coppola, H. Graafsma, C. Caleman, M. J. Bogan, F. R. Maia, S. W. Epp, A. Rocker, L. Foucar, J. Hajdu, G. Weidenspointner, B. Rudek, M. Barthelmess, S. Marchesini, A. Barty, I. Schlichting, R. B. Doak, D. P. DePonte, B. Erk, L. Lomb, J. M. Claverie, S. Bajt, O. Jonsson, H. Soltau, C. Reich, M. M. Seibert, G. Hauser, T. A. White, R. Hartmann, D. Rolles, H. Gorke, C. Bostedt, M. Hantke, F. Krasniqi, S. Stern, A. Martin, K. U. Kuhnel, J. D. Bozek, T. Gorkhover, B. Nilsson, M. Adolph, J. Ullrich, S. Herrmann, A. Aquila, I. Andersson, R. Andritschke, D. Odic, G. Schaller, J. Krzywinski, R. L. Shoeman, D. Starodub, N. Kimmel, H. Hirsemann, C. D. Schroter, M. Liang, F. Schopper, A. Rudenko, L. Gumprecht, D. Pietschner, G. Williams, V. Seltzer, C. Abergel, M. Bott, D. Westphal, S. Schorb, A. Homke, K. O. Hodgson, J. Andreasson, R. G. Sierra, T. Ekeberg, B. Iwan, L. Struder, J. Schulz, S. Boutet, A. A. Miahnahri, P. Holl, C. Y. Hampton, M. Svenda, G. Potdevin, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://bioxfel.org/resources/294