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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, S. Boutet, I. Schlichting, R. B. Doak, K. Nass, S. Botha, G. J. Williams, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): J. E. Koglin, N. A. Zatsepin, T. A. White, M. Caffrey, R. A. Kirian, S. Basu, D. Wang, I. Grotjohann, C. Wang, V. Katritch, A. Barty, S. T. Shah, K. R. Beyerlein, G. W. Han, R. C. Stevens, D. Wacker, W. Liu, C. Gati, M. M. Seibert, S. Boutet, K. N. Rendek, G. J. Williams, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): C. Caleman, A. Homke, R. Neutze, D. Starodub, L. Gumprecht, J. Andreasson, N. Timneanu, H. Gorke, M. M. Seibert, K. Nass, B. Nilsson, S. Schorb, R. G. Sierra, D. Pietschner, X. Wang, G. Potdevin, M. Bott, J. Ullrich, R. Andritschke, I. Andersson, F. R. Maia, C. Reich, T. Gorkhover, A. Rudenko, S. Boutet, L. Foucar, L. Struder, J. Hajdu, P. Holl, H. Hirsemann, C. Bostedt, S. W. Epp, A. Barty, R. L. Shoeman, D. Rupp, I. Schlichting, N. Kimmel, G. Weidenspointner, M. Liang, G. Hauser, D. P. DePonte, B. Erk, S. Marchesini, G. J. Williams, M. Barthelmess, J. Schulz, R. A. Kirian, F. Krasniqi, C. D. Schroter, T. A. White, A. Rocker, S. Bajt, L. Lomb, J. D. Bozek, O. Jonsson, H. Graafsma, M. Svenda, K. U. Kuhnel, B. Rudek, S. Stern, A. Aquila, R. Hartmann, D. Rolles, N. Coppola, G. Schaller, M. J. Bogan, R. B. Doak, I. Grotjohann, F. Schopper, C. Y. Hampton, T. R. Barends, A. V. Martin, S. Herrmann, M. Adolph, J. Krzywinski, H. Soltau, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): S. Herrmann, R. Andritschke, T. Gorkhover, F. Krasniqi, L. Lomb, B. Nilsson, J. D. Bozek, O. Jonsson, A. Aquila, H. Gorke, M. M. Seibert, D. Odic, R. L. Shoeman, K. U. Kuhnel, A. Rudenko, I. Andersson, D. Starodub, G. Schaller, M. Hantke, C. D. Schroter, J. Ullrich, S. Schorb, R. G. Sierra, V. Seltzer, D. Pietschner, F. Schopper, M. Adolph, C. Abergel, J. Krzywinski, A. Homke, H. Hirsemann, T. Ekeberg, S. Boutet, L. Gumprecht, B. Iwan, J. Andreasson, N. Kimmel, A. A. Miahnahri, G. Williams, M. Liang, C. Y. Hampton, D. Westphal, S. W. Epp, R. Kirian, D. Rupp, G. Potdevin, M. Bott, C. Caleman, J. Schulz, K. O. Hodgson, A. Rocker, S. Marchesini, R. B. Doak, M. Svenda, D. P. DePonte, F. R. Maia, L. Struder, B. Rudek, J. Hajdu, P. Holl, A. Barty, H. Graafsma, T. A. White, S. Bajt, L. Foucar, B. Erk, I. Schlichting, N. Coppola, G. Weidenspointner, M. J. Bogan, C. Reich, S. Stern, R. Hartmann, D. Rolles, G. Hauser, M. Barthelmess, C. Bostedt, J. M. Claverie, A. Martin, H. Soltau, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://bioxfel.org/resources/294
