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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): S. Boutet, I. Schlichting, R. B. Doak, K. Nass, S. Botha, G. J. Williams, J. E. Koglin, T. R. Barends, R. L. Shoeman, L. Foucar, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): S. T. Shah, M. Caffrey, D. Wang, W. Liu, R. A. Kirian, R. C. Stevens, C. Wang, I. Grotjohann, S. Boutet, K. R. Beyerlein, G. W. Han, A. Barty, D. Wacker, C. Gati, T. A. White, M. M. Seibert, S. Basu, K. N. Rendek, G. J. Williams, V. Katritch, N. A. Zatsepin, J. E. Koglin, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): R. G. Sierra, X. Wang, S. Schorb, G. Weidenspointner, D. Rupp, M. Barthelmess, C. Bostedt, R. A. Kirian, I. Schlichting, A. Barty, T. Gorkhover, S. Boutet, D. P. DePonte, L. Lomb, J. Schulz, B. Erk, O. Jonsson, G. Hauser, M. Svenda, G. J. Williams, R. L. Shoeman, S. W. Epp, J. D. Bozek, A. Rocker, N. Coppola, H. Graafsma, F. Krasniqi, M. J. Bogan, K. U. Kuhnel, C. D. Schroter, R. B. Doak, S. Marchesini, G. Schaller, D. Rolles, M. Adolph, B. Rudek, I. Grotjohann, A. Aquila, T. A. White, S. Bajt, L. Gumprecht, J. Krzywinski, A. V. Martin, N. Timneanu, H. Soltau, F. Schopper, M. M. Seibert, C. Y. Hampton, R. Hartmann, S. Stern, A. Homke, H. Gorke, D. Starodub, M. Bott, K. Nass, C. Caleman, R. Andritschke, J. Andreasson, T. R. Barends, S. Herrmann, G. Potdevin, D. Pietschner, L. Struder, J. Ullrich, B. Nilsson, P. Holl, I. Andersson, R. Neutze, J. Hajdu, A. Rudenko, N. Kimmel, H. Hirsemann, F. R. Maia, M. Liang, L. Foucar, C. Reich, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): T. Ekeberg, S. Boutet, M. Liang, F. Schopper, D. Odic, L. Gumprecht, J. Krzywinski, B. Nilsson, N. Kimmel, H. Hirsemann, A. Aquila, S. W. Epp, R. Kirian, C. D. Schroter, K. O. Hodgson, J. Andreasson, A. Rudenko, G. Williams, D. Starodub, M. Bott, D. Westphal, R. B. Doak, S. Marchesini, A. Homke, M. Svenda, G. Potdevin, D. Pietschner, L. Struder, J. Schulz, C. Abergel, P. Holl, T. A. White, S. Bajt, M. J. Bogan, F. R. Maia, C. Y. Hampton, L. Foucar, J. Hajdu, B. Iwan, N. Coppola, H. Graafsma, A. A. Miahnahri, S. Stern, R. Hartmann, I. Schlichting, A. Rocker, G. Weidenspointner, D. Rupp, M. Barthelmess, C. Caleman, R. Andritschke, T. Gorkhover, S. Herrmann, A. Barty, M. M. Seibert, G. Hauser, D. P. DePonte, L. Lomb, J. M. Claverie, B. Rudek, O. Jonsson, H. Soltau, R. L. Shoeman, F. Krasniqi, C. Reich, K. U. Kuhnel, J. D. Bozek, B. Erk, H. Gorke, M. Hantke, R. G. Sierra, V. Seltzer, S. Schorb, I. Andersson, A. Martin, G. Schaller, D. Rolles, M. Adolph, J. Ullrich, C. Bostedt, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://bioxfel.org/resources/294
