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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): I. Schlichting, S. Boutet, R. B. Doak, K. Nass, G. J. Williams, S. Botha, T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): M. Caffrey, V. Katritch, D. Wang, R. A. Kirian, S. T. Shah, I. Grotjohann, C. Wang, W. Liu, R. C. Stevens, A. Barty, K. R. Beyerlein, G. W. Han, D. Wacker, S. Boutet, C. Gati, M. M. Seibert, K. N. Rendek, G. J. Williams, T. A. White, J. E. Koglin, N. A. Zatsepin, S. Basu, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): A. Barty, J. Krzywinski, D. Rupp, H. Soltau, C. Bostedt, S. Stern, R. Andritschke, R. Hartmann, M. Bott, K. Nass, G. Hauser, J. Andreasson, D. P. DePonte, H. Gorke, B. Erk, T. R. Barends, L. Struder, S. Herrmann, P. Holl, I. Andersson, C. D. Schroter, G. Potdevin, A. Rocker, J. Ullrich, F. Krasniqi, M. Liang, R. Neutze, N. Kimmel, L. Foucar, A. Aquila, J. Hajdu, D. Rolles, H. Hirsemann, B. Rudek, S. Schorb, R. A. Kirian, R. G. Sierra, X. Wang, M. Barthelmess, I. Schlichting, C. Y. Hampton, G. Weidenspointner, A. V. Martin, F. Schopper, M. Svenda, T. Gorkhover, L. Lomb, S. Boutet, O. Jonsson, C. Caleman, G. J. Williams, A. Homke, J. Schulz, D. Starodub, S. W. Epp, R. B. Doak, R. L. Shoeman, N. Coppola, M. J. Bogan, K. U. Kuhnel, J. D. Bozek, D. Pietschner, H. Graafsma, B. Nilsson, M. Adolph, S. Marchesini, I. Grotjohann, C. Reich, G. Schaller, A. Rudenko, F. R. Maia, M. M. Seibert, T. A. White, L. Gumprecht, S. Bajt, N. Timneanu, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): I. Andersson, G. Schaller, M. Adolph, R. L. Shoeman, J. Ullrich, C. Y. Hampton, B. Iwan, A. A. Miahnahri, F. Schopper, S. Schorb, L. Gumprecht, R. G. Sierra, J. Krzywinski, N. Kimmel, H. Hirsemann, V. Seltzer, M. Liang, C. Caleman, A. Rocker, D. Rupp, J. Andreasson, G. Williams, T. Ekeberg, M. Bott, D. Westphal, S. Boutet, K. O. Hodgson, A. Barty, D. P. DePonte, B. Rudek, M. Svenda, G. Potdevin, S. W. Epp, L. Struder, R. Kirian, J. Schulz, P. Holl, C. Reich, B. Erk, L. Foucar, R. B. Doak, J. Hajdu, N. Coppola, H. Graafsma, M. J. Bogan, F. R. Maia, S. Marchesini, A. Martin, D. Rolles, C. Bostedt, I. Schlichting, G. Weidenspointner, T. A. White, M. Barthelmess, S. Bajt, A. Aquila, D. Odic, B. Nilsson, G. Hauser, S. Stern, L. Lomb, R. Hartmann, J. M. Claverie, O. Jonsson, H. Soltau, M. M. Seibert, C. D. Schroter, A. Rudenko, D. Starodub, R. Andritschke, J. D. Bozek, H. Gorke, T. Gorkhover, M. Hantke, F. Krasniqi, S. Herrmann, K. U. Kuhnel, A. Homke, D. Pietschner, C. Abergel, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://bioxfel.org/resources/294
