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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, S. Boutet, I. Schlichting, R. B. Doak, K. Nass, S. Botha, G. J. Williams, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): D. Wacker, T. A. White, C. Gati, M. M. Seibert, S. Basu, K. N. Rendek, G. J. Williams, V. Katritch, J. E. Koglin, N. A. Zatsepin, S. T. Shah, M. Caffrey, W. Liu, R. C. Stevens, D. Wang, R. A. Kirian, I. Grotjohann, C. Wang, S. Boutet, A. Barty, K. R. Beyerlein, G. W. Han, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): T. Gorkhover, L. Lomb, S. Boutet, O. Jonsson, J. Krzywinski, M. Svenda, H. Soltau, C. Y. Hampton, A. V. Martin, F. Schopper, S. W. Epp, R. B. Doak, K. Nass, R. L. Shoeman, N. Coppola, J. Andreasson, M. J. Bogan, H. Gorke, A. Homke, D. Starodub, C. Caleman, I. Andersson, M. Adolph, G. Potdevin, S. Marchesini, J. Ullrich, D. Pietschner, B. Nilsson, T. A. White, L. Gumprecht, L. Foucar, S. Bajt, N. Timneanu, J. Hajdu, M. M. Seibert, H. Hirsemann, C. Reich, A. Rudenko, F. R. Maia, R. Hartmann, I. Schlichting, M. Bott, G. Weidenspointner, S. Stern, R. Andritschke, A. Barty, D. Rupp, C. Bostedt, T. R. Barends, L. Struder, G. J. Williams, S. Herrmann, P. Holl, J. Schulz, D. P. DePonte, B. Erk, G. Hauser, K. U. Kuhnel, R. Neutze, N. Kimmel, J. D. Bozek, M. Liang, H. Graafsma, C. D. Schroter, A. Rocker, F. Krasniqi, R. G. Sierra, I. Grotjohann, X. Wang, M. Barthelmess, G. Schaller, S. Schorb, R. A. Kirian, A. Aquila, D. Rolles, B. Rudek, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): S. W. Epp, K. O. Hodgson, R. Kirian, I. Schlichting, M. Bott, G. Weidenspointner, C. Caleman, A. Rocker, D. Rupp, S. Marchesini, P. Holl, J. M. Claverie, R. B. Doak, M. Svenda, H. Soltau, L. Struder, G. Hauser, A. Barty, D. P. DePonte, B. Rudek, M. J. Bogan, H. Gorke, T. A. White, L. Foucar, F. Krasniqi, S. Bajt, N. Coppola, J. D. Bozek, C. Reich, B. Erk, S. Stern, J. Ullrich, R. Hartmann, I. Andersson, M. Barthelmess, G. Schaller, C. Bostedt, A. Martin, D. Rolles, J. Krzywinski, R. Andritschke, M. M. Seibert, H. Hirsemann, T. Gorkhover, L. Lomb, F. Schopper, S. Herrmann, O. Jonsson, A. Aquila, D. Odic, B. Nilsson, M. Hantke, G. Williams, K. U. Kuhnel, D. Westphal, R. L. Shoeman, J. Andreasson, C. D. Schroter, A. Rudenko, D. Starodub, S. Schorb, J. Schulz, R. G. Sierra, V. Seltzer, M. Adolph, G. Potdevin, C. Abergel, A. Homke, D. Pietschner, M. Liang, H. Graafsma, T. Ekeberg, L. Gumprecht, F. R. Maia, S. Boutet, N. Kimmel, J. Hajdu, A. A. Miahnahri, C. Y. Hampton, B. Iwan, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://bioxfel.org/resources/294
