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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): J. E. Koglin, T. R. Barends, R. L. Shoeman, L. Foucar, I. Schlichting, S. Boutet, R. B. Doak, K. Nass, G. J. Williams, S. Botha, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): S. Basu, D. Wacker, V. Katritch, C. Gati, M. M. Seibert, S. T. Shah, K. N. Rendek, G. J. Williams, W. Liu, R. C. Stevens, J. E. Koglin, N. A. Zatsepin, M. Caffrey, S. Boutet, D. Wang, R. A. Kirian, C. Wang, I. Grotjohann, T. A. White, A. Barty, K. R. Beyerlein, G. W. Han, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): T. R. Barends, G. Potdevin, S. Herrmann, J. Ullrich, I. Andersson, L. Struder, C. Y. Hampton, A. V. Martin, P. Holl, F. Schopper, R. Neutze, J. Hajdu, H. Hirsemann, L. Foucar, A. Homke, N. Kimmel, M. Liang, D. Starodub, C. Caleman, X. Wang, G. Weidenspointner, S. Schorb, R. G. Sierra, I. Schlichting, M. Barthelmess, D. Pietschner, B. Nilsson, R. A. Kirian, S. Boutet, J. Schulz, T. Gorkhover, G. J. Williams, L. Lomb, C. Reich, A. Rudenko, O. Jonsson, M. Svenda, F. R. Maia, R. L. Shoeman, J. D. Bozek, H. Graafsma, S. W. Epp, K. U. Kuhnel, A. Barty, N. Coppola, M. J. Bogan, D. Rupp, C. Bostedt, R. B. Doak, G. Schaller, S. Marchesini, I. Grotjohann, M. Adolph, D. P. DePonte, B. Erk, G. Hauser, S. Bajt, J. Krzywinski, H. Soltau, T. A. White, A. Rocker, N. Timneanu, M. M. Seibert, F. Krasniqi, L. Gumprecht, C. D. Schroter, H. Gorke, S. Stern, K. Nass, R. Hartmann, J. Andreasson, A. Aquila, M. Bott, D. Rolles, B. Rudek, R. Andritschke, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): F. Krasniqi, R. L. Shoeman, J. D. Bozek, H. Gorke, K. U. Kuhnel, C. Caleman, A. Rocker, M. Hantke, D. Rupp, R. G. Sierra, I. Andersson, V. Seltzer, G. Schaller, S. Schorb, J. Ullrich, A. Barty, M. Adolph, D. P. DePonte, B. Rudek, T. Ekeberg, F. Schopper, S. Boutet, J. Krzywinski, H. Hirsemann, L. Gumprecht, C. Reich, B. Erk, N. Kimmel, M. Liang, R. Kirian, J. Andreasson, G. Williams, S. W. Epp, D. Westphal, K. O. Hodgson, C. Bostedt, A. Martin, M. Bott, D. Rolles, R. B. Doak, G. Potdevin, S. Marchesini, J. Schulz, A. Aquila, M. Svenda, L. Struder, D. Odic, B. Nilsson, P. Holl, T. A. White, F. R. Maia, S. Bajt, J. Hajdu, H. Graafsma, L. Foucar, C. D. Schroter, A. Rudenko, N. Coppola, M. J. Bogan, D. Starodub, R. Hartmann, I. Schlichting, G. Weidenspointner, S. Stern, A. Homke, M. Barthelmess, D. Pietschner, C. Abergel, T. Gorkhover, G. Hauser, S. Herrmann, J. M. Claverie, R. Andritschke, H. Soltau, A. A. Miahnahri, M. M. Seibert, L. Lomb, C. Y. Hampton, B. Iwan, O. Jonsson, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://bioxfel.org/resources/294
