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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): J. E. Koglin, T. R. Barends, R. L. Shoeman, L. Foucar, I. Schlichting, S. Boutet, R. B. Doak, K. Nass, G. J. Williams, S. Botha, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): R. C. Stevens, C. Gati, M. M. Seibert, W. Liu, K. N. Rendek, G. J. Williams, J. E. Koglin, S. Boutet, N. A. Zatsepin, M. Caffrey, T. A. White, D. Wang, R. A. Kirian, S. Basu, C. Wang, I. Grotjohann, A. Barty, K. R. Beyerlein, V. Katritch, G. W. Han, S. T. Shah, D. Wacker, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): G. J. Williams, A. Homke, J. Schulz, D. Starodub, M. Adolph, C. Caleman, T. A. White, S. Bajt, J. D. Bozek, M. M. Seibert, D. Pietschner, H. Graafsma, L. Gumprecht, B. Nilsson, K. U. Kuhnel, N. Timneanu, S. Stern, R. Hartmann, C. Reich, G. Schaller, R. Andritschke, A. Rudenko, F. R. Maia, I. Grotjohann, M. Bott, T. R. Barends, S. Herrmann, P. Holl, A. Barty, J. Krzywinski, D. Rupp, H. Soltau, L. Struder, C. Bostedt, R. Neutze, J. Andreasson, M. Liang, D. P. DePonte, H. Gorke, B. Erk, K. Nass, N. Kimmel, G. Hauser, S. Schorb, R. G. Sierra, X. Wang, G. Potdevin, R. A. Kirian, A. Rocker, J. Ullrich, F. Krasniqi, I. Andersson, M. Barthelmess, C. D. Schroter, T. Gorkhover, S. Boutet, A. Aquila, J. Hajdu, M. Svenda, D. Rolles, H. Hirsemann, L. Lomb, B. Rudek, L. Foucar, O. Jonsson, S. W. Epp, R. L. Shoeman, M. J. Bogan, C. Y. Hampton, G. Weidenspointner, R. B. Doak, A. V. Martin, N. Coppola, F. Schopper, I. Schlichting, S. Marchesini, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): D. Westphal, N. Coppola, A. Barty, J. Andreasson, M. J. Bogan, D. P. DePonte, G. Williams, L. Foucar, B. Rudek, S. Stern, R. Hartmann, M. Barthelmess, C. Reich, G. Potdevin, B. Erk, J. Schulz, S. Herrmann, R. Andritschke, T. Gorkhover, C. Bostedt, F. R. Maia, O. Jonsson, A. Martin, J. Hajdu, M. M. Seibert, D. Rolles, H. Graafsma, L. Lomb, R. L. Shoeman, A. Aquila, I. Schlichting, M. Hantke, D. Odic, G. Weidenspointner, K. U. Kuhnel, B. Nilsson, V. Seltzer, S. Schorb, R. G. Sierra, H. Soltau, M. Adolph, C. D. Schroter, G. Hauser, A. Rudenko, J. M. Claverie, D. Starodub, S. Boutet, T. Ekeberg, F. Krasniqi, N. Kimmel, A. Homke, J. D. Bozek, M. Liang, D. Pietschner, H. Gorke, L. Gumprecht, C. Abergel, S. W. Epp, R. Kirian, A. A. Miahnahri, I. Andersson, M. Bott, C. Y. Hampton, G. Schaller, K. O. Hodgson, B. Iwan, J. Ullrich, S. Marchesini, R. B. Doak, L. Struder, C. Caleman, F. Schopper, P. Holl, A. Rocker, J. Krzywinski, M. Svenda, D. Rupp, H. Hirsemann, S. Bajt, T. A. White, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://bioxfel.org/resources/294
