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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): S. Boutet, I. Schlichting, R. B. Doak, K. Nass, G. J. Williams, S. Botha, T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): M. Caffrey, R. A. Kirian, D. Wang, S. Boutet, I. Grotjohann, C. Wang, A. Barty, K. R. Beyerlein, G. W. Han, T. A. White, D. Wacker, S. Basu, C. Gati, M. M. Seibert, V. Katritch, K. N. Rendek, G. J. Williams, S. T. Shah, J. E. Koglin, N. A. Zatsepin, R. C. Stevens, W. Liu, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): C. Bostedt, A. Barty, R. Neutze, L. Struder, D. Rupp, P. Holl, J. D. Bozek, H. Graafsma, K. U. Kuhnel, M. Liang, G. Hauser, R. G. Sierra, D. P. DePonte, X. Wang, N. Kimmel, B. Erk, S. Schorb, G. Schaller, I. Grotjohann, R. A. Kirian, C. D. Schroter, T. Gorkhover, A. Rocker, S. Boutet, M. Barthelmess, F. Krasniqi, J. Krzywinski, H. Soltau, M. Svenda, A. Aquila, R. L. Shoeman, L. Lomb, D. Rolles, O. Jonsson, B. Rudek, S. W. Epp, J. Andreasson, H. Gorke, K. Nass, F. Schopper, R. B. Doak, C. Y. Hampton, N. Coppola, A. V. Martin, S. Marchesini, M. J. Bogan, G. Potdevin, J. Ullrich, I. Andersson, C. Caleman, T. A. White, A. Homke, S. Bajt, M. Adolph, D. Starodub, J. Hajdu, H. Hirsemann, L. Foucar, M. M. Seibert, R. Hartmann, L. Gumprecht, D. Pietschner, N. Timneanu, B. Nilsson, S. Stern, G. Weidenspointner, I. Schlichting, R. Andritschke, C. Reich, T. R. Barends, A. Rudenko, S. Herrmann, M. Bott, F. R. Maia, G. J. Williams, J. Schulz, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): B. Nilsson, S. Schorb, M. Hantke, A. Aquila, R. G. Sierra, K. U. Kuhnel, D. Odic, V. Seltzer, G. Potdevin, J. Schulz, M. Adolph, D. Starodub, C. D. Schroter, T. Ekeberg, A. Rudenko, S. Boutet, F. R. Maia, J. Hajdu, H. Graafsma, N. Kimmel, C. Abergel, S. W. Epp, M. Liang, A. Homke, R. Kirian, L. Gumprecht, D. Pietschner, I. Schlichting, G. Weidenspointner, M. Bott, A. A. Miahnahri, R. B. Doak, K. O. Hodgson, C. Y. Hampton, B. Iwan, S. Marchesini, H. Soltau, G. Hauser, J. M. Claverie, D. Rupp, P. Holl, C. Caleman, T. A. White, M. Svenda, A. Rocker, S. Bajt, L. Struder, F. Krasniqi, J. D. Bozek, H. Gorke, N. Coppola, B. Rudek, S. Stern, M. J. Bogan, A. Barty, R. Hartmann, L. Foucar, D. P. DePonte, I. Andersson, G. Schaller, J. Ullrich, M. Barthelmess, R. Andritschke, C. Reich, T. Gorkhover, B. Erk, S. Herrmann, F. Schopper, J. Krzywinski, H. Hirsemann, O. Jonsson, C. Bostedt, M. M. Seibert, A. Martin, R. L. Shoeman, L. Lomb, D. Rolles, D. Westphal, J. Andreasson, G. Williams, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://bioxfel.org/resources/294
