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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): I. Schlichting, S. Boutet, R. B. Doak, K. Nass, G. J. Williams, S. Botha, T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): M. Caffrey, S. Boutet, R. A. Kirian, D. Wang, I. Grotjohann, C. Wang, T. A. White, A. Barty, K. R. Beyerlein, G. W. Han, S. Basu, D. Wacker, V. Katritch, C. Gati, M. M. Seibert, S. T. Shah, K. N. Rendek, G. J. Williams, R. C. Stevens, W. Liu, J. E. Koglin, N. A. Zatsepin, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): N. Coppola, A. Barty, M. J. Bogan, D. Rupp, R. B. Doak, C. Bostedt, I. Grotjohann, G. Schaller, S. Marchesini, G. Hauser, M. Adolph, D. P. DePonte, B. Erk, S. Bajt, J. Krzywinski, H. Soltau, T. A. White, C. D. Schroter, N. Timneanu, A. Rocker, M. M. Seibert, F. Krasniqi, L. Gumprecht, J. Andreasson, H. Gorke, S. Stern, R. Hartmann, K. Nass, A. Aquila, M. Bott, D. Rolles, R. Andritschke, B. Rudek, I. Andersson, T. R. Barends, G. Potdevin, S. Herrmann, J. Ullrich, L. Struder, C. Y. Hampton, P. Holl, A. V. Martin, F. Schopper, R. Neutze, L. Foucar, J. Hajdu, H. Hirsemann, C. Caleman, N. Kimmel, A. Homke, M. Liang, D. Starodub, I. Schlichting, X. Wang, G. Weidenspointner, S. Schorb, R. G. Sierra, M. Barthelmess, D. Pietschner, R. A. Kirian, B. Nilsson, G. J. Williams, S. Boutet, J. Schulz, T. Gorkhover, L. Lomb, C. Reich, O. Jonsson, A. Rudenko, M. Svenda, F. R. Maia, R. L. Shoeman, K. U. Kuhnel, J. D. Bozek, H. Graafsma, S. W. Epp, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): M. Svenda, A. Aquila, L. Struder, D. Odic, P. Holl, B. Nilsson, H. Graafsma, T. A. White, F. R. Maia, S. Bajt, J. Hajdu, D. Starodub, L. Foucar, C. D. Schroter, N. Coppola, A. Rudenko, M. J. Bogan, R. Hartmann, I. Schlichting, G. Weidenspointner, S. Stern, C. Abergel, A. Homke, M. Barthelmess, D. Pietschner, H. Soltau, T. Gorkhover, G. Hauser, S. Herrmann, R. Andritschke, J. M. Claverie, M. M. Seibert, A. A. Miahnahri, L. Lomb, C. Y. Hampton, O. Jonsson, B. Iwan, H. Gorke, F. Krasniqi, R. L. Shoeman, J. D. Bozek, K. U. Kuhnel, C. Caleman, A. Rocker, M. Hantke, D. Rupp, R. G. Sierra, J. Ullrich, I. Andersson, V. Seltzer, G. Schaller, S. Schorb, B. Rudek, A. Barty, M. Adolph, D. P. DePonte, H. Hirsemann, T. Ekeberg, F. Schopper, S. Boutet, J. Krzywinski, L. Gumprecht, C. Reich, N. Kimmel, B. Erk, M. Liang, D. Westphal, R. Kirian, J. Andreasson, G. Williams, S. W. Epp, K. O. Hodgson, C. Bostedt, A. Martin, M. Bott, D. Rolles, R. B. Doak, J. Schulz, G. Potdevin, S. Marchesini, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://bioxfel.org/resources/294
