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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): R. B. Doak, K. Nass, G. J. Williams, S. Botha, T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, I. Schlichting, S. Boutet, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): S. T. Shah, M. Caffrey, D. Wang, W. Liu, R. A. Kirian, R. C. Stevens, I. Grotjohann, C. Wang, A. Barty, S. Boutet, K. R. Beyerlein, G. W. Han, D. Wacker, C. Gati, T. A. White, M. M. Seibert, S. Basu, K. N. Rendek, G. J. Williams, J. E. Koglin, V. Katritch, N. A. Zatsepin, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): M. Barthelmess, R. A. Kirian, A. Barty, G. Weidenspointner, S. Stern, D. Rupp, R. Hartmann, C. Bostedt, I. Schlichting, L. Lomb, O. Jonsson, M. Svenda, S. Herrmann, D. P. DePonte, J. Schulz, B. Erk, T. R. Barends, G. Hauser, G. J. Williams, N. Coppola, M. J. Bogan, R. B. Doak, C. D. Schroter, J. D. Bozek, A. Rocker, H. Graafsma, F. Krasniqi, K. U. Kuhnel, R. Neutze, M. Adolph, A. Aquila, G. Schaller, S. Schorb, D. Rolles, R. G. Sierra, B. Rudek, I. Grotjohann, X. Wang, L. Gumprecht, N. Timneanu, M. M. Seibert, S. Boutet, C. Y. Hampton, J. Krzywinski, A. V. Martin, H. Soltau, T. Gorkhover, F. Schopper, M. Bott, R. Andritschke, A. Homke, H. Gorke, S. W. Epp, D. Starodub, K. Nass, R. L. Shoeman, C. Caleman, J. Andreasson, L. Struder, P. Holl, G. Potdevin, S. Marchesini, D. Pietschner, J. Ullrich, B. Nilsson, I. Andersson, N. Kimmel, M. Liang, C. Reich, J. Hajdu, A. Rudenko, H. Hirsemann, T. A. White, F. R. Maia, L. Foucar, S. Bajt, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): M. Liang, L. Gumprecht, N. Kimmel, T. Gorkhover, A. Aquila, F. Schopper, S. Herrmann, D. Odic, J. Krzywinski, R. Andritschke, B. Nilsson, H. Hirsemann, K. O. Hodgson, M. Bott, R. L. Shoeman, C. D. Schroter, J. Andreasson, A. Rudenko, G. Williams, D. Starodub, D. Westphal, M. Svenda, L. Struder, P. Holl, C. Abergel, V. Seltzer, A. Homke, G. Potdevin, S. Schorb, D. Pietschner, J. Schulz, R. G. Sierra, L. Foucar, N. Coppola, M. J. Bogan, A. A. Miahnahri, F. R. Maia, S. Boutet, C. Y. Hampton, J. Hajdu, B. Iwan, H. Graafsma, T. Ekeberg, M. Barthelmess, R. Kirian, C. Caleman, I. Schlichting, A. Rocker, G. Weidenspointner, S. W. Epp, D. Rupp, M. M. Seibert, L. Lomb, O. Jonsson, A. Barty, G. Hauser, S. Marchesini, D. P. DePonte, J. M. Claverie, R. B. Doak, B. Rudek, H. Soltau, K. U. Kuhnel, M. Hantke, F. Krasniqi, S. Bajt, C. Reich, J. D. Bozek, B. Erk, H. Gorke, T. A. White, M. Adolph, C. Bostedt, I. Andersson, A. Martin, G. Schaller, S. Stern, D. Rolles, J. Ullrich, R. Hartmann, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://bioxfel.org/resources/294